VCAM-1

VCAM-1 분자 정보

영어 이름Vascular cell adhesion molecule 1시판 약물 수2
임상 약물 수1표적 별명VCAM1,Vascular cell adhesion protein 1,V-CAM 1,CD106,Vascular Cell Adhesion Molecule 1,CD106 Antigen,INCAM-100,VCAM-1,Vascular Cell Adhesion Molecule-1
최고 연구 개발 단계Approved
영어 이름Vascular cell adhesion molecule 1
표적 별명VCAM1,Vascular cell adhesion protein 1,V-CAM 1,CD106,Vascular Cell Adhesion Molecule 1,CD106 Antigen,INCAM-100,VCAM-1,Vascular Cell Adhesion Molecule-1
시판 약물 수2
임상 약물 수1
최고 연구 개발 단계Approved

VCAM-1분자 배경

Vascular cell adhesion protein 1 (VCAM1) is also known as CD106, INCAM-100 and L1CAM, is a cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. VCAM1 / CD106 contains 7 Ig-like C2-type (immunoglobulin-like) domains. CD106 / VCAM-1 is expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue. L1CAM / VCAM-1 is Important in cell-cell recognition and appears to function in leukocyte-endothelial cell adhesion. CD106 / VCAM1 interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1 / VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. INCAM-100 / VCAM1 binds to ECMV-D capsid proteins and acts as a receptor for this virus.

VCAM-1분자 별명

VCAM1,CD106,INCAM-100,V-CAM 1,VCAM-1

임상 약물 정보

영어 이름연구 코드연구 개발 단계회사적응증임상 시험
99mTc-cAbVCAM1-599mTccAbVCAM1‐5; 99mTc-cAbVCAM1-5Phase 1 ClinicalMedico-Economic Evaluation Unit , University Hospital, GrenobleAtherosclerosis; Cardiovascular Diseases
상세

시판 약물 정보

영어 이름연구 코드연구 개발 단계회사가장 빠른 브랜드 이름가장 빠른 승인 국가가장 빠른 적응증가장 빠른 승인 회사가장 빠른 승인 날짜적응증임상 시험
Tocopherol acetateDSE-9912ApprovedNational Institute Of Diabetes And Digestive And Kidney DiseasesEphynal, Aquasol EJapanVitamin E Deficiency; Diabetic Retinopathy; Atherosclerosis; Intermittent Claudication; Venous Thromboembolism; ThrombosisEisai Co Ltd1951-09-01Atherosclerosis; Diabetic Retinopathy; Intermittent Claudication; Metabolic Dysfunction-Associated Steatotic Liver Disease; Thrombosis; Venous Thromboembolism; Vitamin E Deficiency
상세
Ascorbic Acid/Biotin/Cholecalciferol/Cyanocobalamin/Dexpanthenol/Folic acid/Niacinamide/Pyridoxine/Riboflavin/Thiamine/Tocopherol Acetate/Vitamin A/Vitamin KApprovedSandoz Canada IncInfuvite PediatricUnited StatesAvitaminosisSandoz Canada Inc2001-02-21Avitaminosis
상세
  • 분자 정보
  • 제품 목록
  • 시판 약물 정보
  • 임상 약물 정보