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Menu
Home PageAll MoleculesUL18 & B2M
UL18 & B2M
UL18 & B2M Product List
- Product Category
Protein (1)
- Product Status
Launched (1)
- Species
Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) & Human (1)
- Tag
His Tag & Avi Tag (1)
- Conjugate
Biotin-labeled (1)
| Cat. No. | Species | Host | Product Description | Structure | Purity | Feature |
|---|---|---|---|---|---|---|
ULM-V82W3 | Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) & Human | HEK293 | Biotinylated Human cytomegalovirus (strain AD169) (HHV-5) & Human UL18 & B2M Heterodimer Protein, His,Avitag™&Tag Free (MALS verified) |  |  |  |
Total: 1
- 1
UL18 & B2M Background
Human cytomegalovirus (HCMV) encodes UL18, a viral MHC‑I homolog that mimics human HLA class I molecules. UL18 forms a stable heterodimer with human β2‑microglobulin (B2M), enabling proper folding and high‑affinity interaction with the inhibitory receptor LIR‑1/ILT2 on immune cells. This interaction suppresses NK‑cell activation and contributes to HCMV immune evasion. Recombinant UL18–B2M complexes are widely used to study viral immunomodulation and receptor–ligand interactions.
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