UBE1 분자 정보
Molecule Name
Ubiquitin-like modifier-activating enzyme 1
분자 별명
A1S9T and BN75 temperature sensitivity complementing,A1S9T,A1ST,AMCX1,GXP1,MGC4781,POC20 centriolar protein homolog,POC20,Protein A1S9,SMAX2,UBA1,UBA1, ubiquitin-activating enzyme E1 homolog A,UBA1A,UBE1,UBE1A1S9,UBE1X,ubiquitin-activating enzyme E1 (A1S9
Drug Development Progress
임상 약물 수1
시판 약물 수0
최고 연구 개발 단계Phase 1 Clinical
표적 별명
EC:6.2.1.45，UBE1，Ubiquitin-Activating Enzyme E1 (A1S9T And BN75 Temperature Sensitivity Complementing)，UBA1， Ubiquitin-Activating Enzyme E1 Homolog (Yeast)，POC20 Centriolar Protein Homolog (Chlamydomonas)，Ubiquitin-Like Modifier Activating Enzyme 1，Testicular Secretory Protein Li 63，EC 6.2.1.45，CFAP124，AMCX1，POC20，SMAX2，UBA1A，UBE1X，A1S9，A1ST，GXP1，Ubiquitin-activating enzyme E1，Protein A1S9，A1S9T，Ubiquitin-like modifier-activating enzyme 1，UBA1，Ubiquitin Like Modifier Activating Enzyme 1，A1S9T And BN75 Temperature Sensitivity Complementing，UBA1， Ubiquitin-Activating Enzyme E1 Homolog A，POC20 Centriolar Protein Homolog
분자 배경
The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]
UBE1 제품 목록
You Have Viewed 0 Of 0 Results
임상 약물 정보
| 영어 이름 | 연구 코드 | 연구 개발 단계 | 회사 | 적응증 | 임상 시험 |
|---|---|---|---|---|---|
| TAK-243 | TAK-243; MLN-7243 | Phase 1 Clinical | Takeda Pharmaceutical Co Ltd | Leukemia, Myeloid, Acute; Lymphoma; Lymphoma, Non-Hodgkin; Myelodysplastic Syndromes; Solid tumours | 상세 |