TREM-1

TREM-1 분자 정보

영어 이름Triggering receptor expressed on myeloid cells 1시판 약물 수0
임상 약물 수6표적 별명Triggering Receptor Expressed On Myeloid Cells 1,CD354 Antigen,Triggering Receptor Expressed on Myeloid Cells-1,TREM-1,TREM1,CD354,Triggering receptor expressed on monocytes 1
최고 연구 개발 단계Phase 2 Clinical
영어 이름Triggering receptor expressed on myeloid cells 1
표적 별명Triggering Receptor Expressed On Myeloid Cells 1,CD354 Antigen,Triggering Receptor Expressed on Myeloid Cells-1,TREM-1,TREM1,CD354,Triggering receptor expressed on monocytes 1
시판 약물 수0
임상 약물 수6
최고 연구 개발 단계Phase 2 Clinical

TREM-1 제품 목록

  • 속성

    Protein (1)

  • 제품 라이브러리

    온라인 (1)

  • 종

    Human (1)

  • 태그

    Fc Tag (1)

  • 마커

    Unconjugated (1)

제품 번호종발현 시스템제품 설명단백질 구조순도특성
Human
HEK293
Human TREM-1 / CD354 Protein, Fc Tag, low endotoxin
총 수량1
  • 1

TREM-1분자 배경

Triggering receptor expressed on myeloid cells 1 (TREM1) is also known as CD antigen CD354, and is a type I transmembrane protein with a single Ig-like domain. TREM1 is highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. TREM-1 / CD354 stimulates neutrophil and monocyte-mediated inflammatory responses, and also triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock. TREM1 can interacts with TYROBP / DAP12.

TREM-1분자 별명

TREM1,CD354

임상 약물 정보

영어 이름연구 코드연구 개발 단계회사적응증임상 시험
NangibotideLR-12Phase 2 ClinicalInotremCoronavirus Disease 2019 (COVID-19); Shock, Septic
상세
ABBV-8736ABBV-8736Phase 2 ClinicalAbbvie IncCrohn Disease; Inflammatory Bowel Diseases
상세
TREM-1 antibody (Boehringer Ingelheim)Phase 1 ClinicalBoehringer Ingelheim International GmbhAutoimmune Diseases
상세
CEL383CEL-383Phase 1 ClinicalCelsius Therapeutics IncInflammatory Bowel Diseases
상세
TREM 1 antibody(Boehringer Ingelheim International Gmbh)TREM 1 antibody(Boehringer Ingelheim International Gmbh)Phase 1 ClinicalBoehringer Ingelheim International GmbhImmune System Diseases
상세
PY-159PY-159Phase 1 ClinicalCentre for the Commercialization of Antibodies and BiologicsNeoplasms; Solid tumours
상세
  • 분자 정보
  • 제품 목록
  • 임상 약물 정보