TIM-4

TIM-4 분자 정보

영어 이름T-cell immunoglobulin and mucin domain-containing protein 4시판 약물 수0
임상 약물 수1표적 별명T-cell immunoglobulin mucin receptor 4 (TIM-4),T-cell membrane protein 4,TIM4
최고 연구 개발 단계Phase 1 Clinical
영어 이름T-cell immunoglobulin and mucin domain-containing protein 4
표적 별명T-cell immunoglobulin mucin receptor 4 (TIM-4),T-cell membrane protein 4,TIM4
시판 약물 수0
임상 약물 수1
최고 연구 개발 단계Phase 1 Clinical

TIM-4 제품 목록

  • 속성

    Protein (1)

  • 제품 라이브러리

    온라인 (1)

  • Human (1)

  • 태그

    His Tag (1)

  • 마커

    Unconjugated (1)

제품 번호발현 시스템제품 설명단백질 구조순도특성
TI4-H52H3
Human
HEK293
Human TIM-4 / TIMD4 Protein, His Tag
총 수량1
  • 1

TIM-4분자 배경

The T cell immunoglobulin mucin (TIM) proteins regulate T cell activation and tolerance. An essential step during clearance of apoptotic cells is the recognition of phosphatidylserine (PS) exposed on apoptotic cells by its receptors on phagocytes. The phosphatidylserine (PS) receptor Tim-4 mediates phagocytosis of apoptotic cells by binding to PS exposed on the surface of these cells, and thus functions as a PS receptor for apoptotic cells. Tim-4 directly binding to PS and functioning as a tethering receptor for phagocytosis of apoptotic cells has been extensively studied over the past decade. However, the molecular mechanisms by which Tim-4 collaborates with other engulfment receptors during efferocytosis remain elusive.

TIM-4분자 별명

TIM4,TIMD4,SMUCKLER

임상 약물 정보

영어 이름연구 코드연구 개발 단계회사적응증임상 시험
LPX-TI641LPX-TI-641Phase 1 ClinicalLAPIX Therapeutics IncArthritis, Psoriatic; Arthritis, Rheumatoid; Autoimmune Diseases; Demyelinating Diseases; Dermatitis, Atopic; Multiple Sclerosis; Neuromyelitis Optica; Psoriasis
상세
  • 제품 목록
  • 임상 약물 정보
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