TDP-43

TDP-43 분자 정보

영어 이름TAR DNA binding protein 43시판 약물 수0
임상 약물 수6표적 별명TAR DNA-binding protein 43,TARDBP,TAR DNA Binding Protein,TDP43,TAR DNA-Binding Protein-43,ALS10
최고 연구 개발 단계Phase 3 Clinical
영어 이름TAR DNA binding protein 43
표적 별명TAR DNA-binding protein 43,TARDBP,TAR DNA Binding Protein,TDP43,TAR DNA-Binding Protein-43,ALS10
시판 약물 수0
임상 약물 수6
최고 연구 개발 단계Phase 3 Clinical

TDP-43 제품 목록

  • 속성

    Protein (1)

  • 제품 라이브러리

    온라인 (1)

  • Human (1)

  • 태그

    His Tag (1)

  • 마커

    Unconjugated (1)

제품 번호발현 시스템제품 설명단백질 구조순도특성
AI Compatible
TD3-H5145
Human
E. coli
Human TDP-43 Protein, His Tag
총 수량1
  • 1

TDP-43분자 배경

TDP-43, the transactive response (TAR)-DNA binding Protein with a molecular weight of 43 KDa is encoded by TARDBP gene that located at the chromosome 1. It is a RNA/DNA binding protein that structurally resembles a typical hnRNP protein family member. involved in transcriptional regulation and RNA processing. It is linked to sporadic and familial amyotrophic lateral sclerosis and frontotemporal lobar degeneration. TDP-43 is predominantly nuclear, but it translocates to the cytoplasm under pathological conditions. Cytoplasmic accumulation, phosphorylation, ubiquitination and truncation of TDP-43 are the main hallmarks of TDP-43 proteinopathies.

TDP-43분자 별명

TAR DNA-binding protein 43

임상 약물 정보

영어 이름연구 코드연구 개발 단계회사적응증임상 시험
MonepantelPPL-1; NUZ-001Phase 3 ClinicalPitney Pharmaceuticals Pty LtdAmyotrophic Lateral Sclerosis; Motor Neuron Disease; Neoplasms
상세
nL-TARD-001nL-TARD-001Phase 2 ClinicalN-Lorem FoundationAmyotrophic Lateral Sclerosis
상세
AMDX-2011PAMDX2011P; AMDX-2011PPhase 2 ClinicalAmydis IncAlzheimer Disease; Amyotrophic Lateral Sclerosis; Cerebral Amyloid Angiopathy; Glaucoma, Open-Angle; Parkinson Disease
상세
VTx-002 (VectorY)VTx-002Phase 2 ClinicalVectorY BVAmyotrophic Lateral Sclerosis
상세
CTx-1000CTx1000; CTx-1000Phase 1 ClinicalCelosia Therapeutics Pty LtdAmyotrophic Lateral Sclerosis
상세
AB-14AB-14Phase 1 ClinicalAutotac Bio IncAmyotrophic Lateral Sclerosis
상세

제품 리뷰

  • n***l2026-04-14
    0사람들이 좋아합니다
    We ordered Human TDP-43 Protein, His Tag and was very happy with the fast shipping to get our project going. Customer service was very helpful on the phone before I placed my order online.
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  • 제품 목록
  • 제품 리뷰
  • 임상 약물 정보
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