언어 선택

Sortilin

Sortilin 분자 정보

영어 이름	Sortilin	시판 약물 수	0
임상 약물 수	3	표적 별명	100 kDa NT receptor，NT3，Glycoprotein 95，LDLCQ6，NTR3，Gp95，Sortilin 1，Neurotensin receptor 3
최고 연구 개발 단계	Phase 2 Clinical

영어 이름	Sortilin
표적 별명	100 kDa NT receptor，NT3，Glycoprotein 95，LDLCQ6，NTR3，Gp95，Sortilin 1，Neurotensin receptor 3
시판 약물 수	0
임상 약물 수	3
최고 연구 개발 단계	Phase 2 Clinical

Sortilin 제품 목록

속성
Protein (5)Cell (1)
제품 라이브러리
온라인 (6)
종
Human (3)Cynomolgus (1)Rat (1)Canine (1)
태그
His Tag (4)His Tag & Avi Tag (1)- (1)
마커
Unconjugated (4)Biotin-labeled (1)- (1)

제품 번호	종	발현 시스템	제품 설명
CHEK-ATP155	Human	HEK293	HEK293/Human SORT1 Stable Cell Line
SON-H52H5	Human	HEK293	Human Sortilin / SORT1 Protein, His Tag, low endotoxin (MALS verified)
SON-H82E9	Human	HEK293	Biotinylated Human Sortilin / SORT1 Protein, His,Avitag™ (MALS & SPR verified)
SON-C52H3	Cynomolgus	HEK293	Cynomolgus Sortilin Protein, His Tag
SON-C52H4	Canine	HEK293	Canine Sortilin Protein, His Tag
SON-R52H3	Rat	HEK293	Rat Sortilin Protein, His Tag (MALS verified)

총 수량6

Sortilin분자 배경

Sortilin is a multifunctional type-I transmembrane protein belonging to the Vps10p-domain receptor family (Vps10p-Domain Receptors, Vps10p-DRs). Sortilin plays a central role in cellular protein sorting, signal transduction, and metabolism. Its dysfunction is closely related to neurodegenerative diseases, metabolic syndrome, and cancer, and it is a potential therapeutic target for diseases.

Sortilin분자 별명

Sortilin,SORT1,100 kDa NT receptor,Glycoprotein 95,Gp95,Gp95LDLCQ6,Neurotensin receptor 3,NT3NTR3,Ntr3,sortilin 1,

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
VES-001	VES001; VES-001	Phase 2 Clinical	Vesper Bio APS	Dementia; Frontotemporal Dementia; Frontotemporal Lobar Degeneration	상세
Latozinemab	AL-001; GSK-4527223	Phase 1 Clinical	Alector Inc, Glaxosmithkline Plc	Amyotrophic Lateral Sclerosis; Frontotemporal Dementia; Neurodegenerative Diseases	상세
ARB-1-6	ARB-1-6; PQ-203	Phase 1 Clinical	ProteinQure Inc	Breast Neoplasms; Solid tumours; Triple Negative Breast Neoplasms	상세