언어 선택

SMO

SMO 분자 정보

영어 이름	Smoothened receptor	시판 약물 수	3
임상 약물 수	5	표적 별명	SMO，SMOH，Smoothened， Frizzled Class Receptor，Smoothened， Frizzled Family Receptor，Frizzled Family Member 11，Protein Gx，Seven Transmembrane Helix Receptor，Smoothened Homolog (Drosophila)，Smoothened Homolog，FZD11，CRJS，Gx，Smoothened Receptor，Smoothened， Seven Transmembrane Spanning Receptor，Smoothened (Drosophila) Homolog
최고 연구 개발 단계	Approved

영어 이름	Smoothened receptor
표적 별명	SMO，SMOH，Smoothened， Frizzled Class Receptor，Smoothened， Frizzled Family Receptor，Frizzled Family Member 11，Protein Gx，Seven Transmembrane Helix Receptor，Smoothened Homolog (Drosophila)，Smoothened Homolog，FZD11，CRJS，Gx，Smoothened Receptor，Smoothened， Seven Transmembrane Spanning Receptor，Smoothened (Drosophila) Homolog
시판 약물 수	3
임상 약물 수	5
최고 연구 개발 단계	Approved

SMO 제품 목록

속성
Protein (2)
제품 라이브러리
온라인 (2)
종
Human (2)
태그
- (2)
마커
Unconjugated (2)

제품 번호	종	발현 시스템	제품 설명	단백질 구조	순도	특성
SMO-H52D3	Human	HEK293	Human SMO Protein, His,Flag Tag (Detergent)
SMO-H52P3	Human	HEK293	Human SMO Full Length Protein (VLP)

총 수량2

SMO분자 배경

The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex.

SMO분자 별명

SMO,smoothened, frizzled class receptor,CRJS, FZD11, Gx, PHLS, SMOH

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Patidegib	SGT-610; BBP-009; FIN-5; IPI-926	Phase 3 Clinical	Infinity Pharmaceuticals Inc	Adenocarcinoma; Basal Cell Nevus Syndrome; Carcinoma, Basal Cell; Chondrosarcoma; Head and Neck Neoplasms; Neoplasms; Pancreatic Neoplasms; Primary Myelofibrosis	상세
Taladegib	ENV-IPF-101; ENV-ONC-101; LY-2940680; ENV-101; RXDX-109	Phase 2 Clinical	Eli Lilly And Company	Breast Neoplasms; Cholangiocarcinoma; Colonic Neoplasms; Idiopathic Pulmonary Fibrosis; Medulloblastoma; Neoplasm Metastasis; Neoplasms; Rhabdomyosarcoma; Sarcoma; Small Cell Lung Carcinoma; Solid tumours	상세
GT-1708F	GT-1708F; GT-1708; GT1708F	Phase 2 Clinical	Suzhou Koshine Biomedica Inc	Hematologic Neoplasms; Idiopathic Pulmonary Fibrosis; Solid tumours	상세
Cipromedegib	SHR-1539	Phase 1 Clinical	Jiangsu Hengrui Medicine Co Ltd	Solid tumours	상세
ZSP-1602	ZSP-1602	Phase 1 Clinical	Guangdong Zhongsheng Pharmaceutical Co Ltd	Carcinoma; Carcinoma, Basal Cell; Carcinoma, Neuroendocrine; Esophageal Neoplasms; Glioblastoma; Glioma; Medulloblastoma; Neoplasms; Neuroendocrine Tumors; Pancreatic Neoplasms; Small Cell Lung Carcinoma; Stomach Neoplasms	상세

시판 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	가장 빠른 브랜드 이름	가장 빠른 승인 국가	가장 빠른 적응증	가장 빠른 승인 회사	가장 빠른 승인 날짜	적응증	임상 시험
Sonidegib Diphosphate	LDE-225; NVP-LDE-225	Approved	Novartis Pharma Ag	Odomzo, 奥昔朵	United States	Carcinoma, Basal Cell	Sun Pharmaceutical Industries Ltd	2015-07-24	Astrocytoma; Basal Cell Nevus Syndrome; Blood Coagulation Disorders; Blood Platelet Disorders; Bone Marrow Diseases; Breast Neoplasms; Carcinoma, Basal Cell; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Esophageal Neoplasms; Gastroesophageal Junction Neoplasms; Glioblastoma; Glioma; Graft vs Host Disease; Hematologic Diseases; Hematologic Neoplasms; Hemorrhagic Disorders; Hepatic Insufficiency; Hepatoblastoma; HR-positive breast cancer; Leukemia; Leukemia, Myelogenous, Chronic; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Liver Cirrhosis; Liver Dysfunction; Lung Neoplasms; Medulloblastoma; Metastatic breast cancer; Multiple Myeloma; Myelodysplastic Syndromes; Myelodysplastic-Myeloproliferative Diseases; Myeloproliferative Disorders; Neuroblastoma; Ovarian Neoplasms; Pancreatic Neoplasms; Polycythemia Vera; Primary Myelofibrosis; Prostatic Neoplasms; Rhabdomyosarcoma; Skin Neoplasms; Solid tumours; Stomach Neoplasms; Thrombocythemia, Essential; Thrombocytosis;	상세
Glasdegib	PF-04; PF-4449913; PF-04449913	Approved	Pfizer Inc	Daurismo	United States	Leukemia, Myeloid, Acute	Pfizer Inc	2018-11-21	Fasciitis; Graft vs Host Disease; Hematologic Neoplasms; Hepatic Insufficiency; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes; Primary Myelofibrosis; Renal Insufficiency; Solid tumours	상세
Vismodegib	R-3616; RG-3616; GDC-0449	Approved	F. Hoffmann-La Roche Ltd, Genentech Inc	Erivedge	United States	Carcinoma, Basal Cell	Genentech Inc	2012-01-30	Adenocarcinoma; Basal Cell Nevus Syndrome; Brain Neoplasms; Breast Neoplasms; Carcinoma, Basal Cell; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Central Nervous System Lymphoma; Chondrosarcoma; Chondrosarcoma, Clear Cell; Chondrosarcoma, Extraskeletal Myxoid; Chondrosarcoma, Mesenchymal; Colorectal Neoplasms; Dermatofibrosarcoma; Desmoplastic Small Round Cell Tumor; Esophageal Neoplasms; Fibrosarcoma; Gastrointestinal Stromal Tumors; Glioblastoma; Gliosarcoma; Graft vs Host Disease; Hemangioendothelioma, Epithelioid; Hemangiosarcoma; Hematologic Neoplasms; Idiopathic Pulmonary Fibrosis; Leiomyosarcoma; Leukemia, Lymphocytic, Chronic, B-Cell; Liposarcoma; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Medulloblastoma; Mesenchymoma; Multiple Myeloma; Neoplasms; Neuroectodermal Tumors, Primitive, Peripheral; Neurofibrosarcoma; Odontogenic Cyst, Calcifying; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Rhabdomyosarcoma; Sarcoma; Sarcoma, Alveolar Soft Part	상세