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Siglec-9

Siglec-9 Overview

English Name	Sialic acid-binding Ig-like lectin 9	Approved Drugs	0
Drugs in Clinical Trials	0	Target Synonym	CDw329，Protein FOAP-9，CD329
Highest Development Stage	Preclinical

English Name	Sialic acid-binding Ig-like lectin 9
Target Synonym	CDw329，Protein FOAP-9，CD329
Approved Drugs	0
Drugs in Clinical Trials	0
Highest Development Stage	Preclinical

Siglec-9 Product List

Product Category
Protein (4)
Product Status
Launched (4)
Species
Human (3)Cynomolgus (1)
Tag
His Tag (2)Fc Tag (1)His Tag & Avi Tag (1)
Conjugate
Unconjugated (3)Biotin-labeled (1)

Cat. No.	Species	Host	Product Description
HOT AIDD‑Ready SI9-H5256	Human	HEK293	Human Siglec-9 Protein, Fc Tag
HOT SI9-H52H4	Human	HEK293	Human Siglec-9 Protein, His Tag, low endotoxin
HOT SI9-H82E9	Human	HEK293	Biotinylated Human Siglec-9 Protein, His,Avitag™
SI9-C52H9	Cynomolgus	HEK293	Cynomolgus Siglec-9 Protein, His Tag

Total: 4

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Siglec-9 Background

siglec-9 (HGMW-approved symbol SIGLEC9) a member of the sialic acid-binding Ig-like lectin (Siglec) family, which belongs to the immunoglobulin superfamily (IgSF). SIGLEC9 shows a high degree of homology to many members of the siglec family, including siglec-7 (80%), siglec-8 (72%), siglec-5 (65%), and CD33 (64%). This high degree of homology is also conserved in the extracellular Ig-like domains. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains。Siglec-9 with a hydrophobic signal peptide, an N-terminal Ig-likeV-type domain, two Ig-like C2-type domains, a transmembrane region and a cytoplasmic tail.