언어 선택

Siglec-7

Siglec-7 분자 정보

영어 이름	Sialic acid-binding Ig-like lectin 7	시판 약물 수	0
임상 약물 수	0	표적 별명	CDw328，AIRM-1，Adhesion inhibitory receptor molecule 1，D-siglec，QA79 membrane protein，CD328
최고 연구 개발 단계	Preclinical

영어 이름	Sialic acid-binding Ig-like lectin 7
표적 별명	CDw328，AIRM-1，Adhesion inhibitory receptor molecule 1，D-siglec，QA79 membrane protein，CD328
시판 약물 수	0
임상 약물 수	0
최고 연구 개발 단계	Preclinical

Siglec-7 제품 목록

속성
Protein (4)
제품 라이브러리
온라인 (4)
종
Human (4)
태그
His Tag (1)His Tag & Avi Tag (1)Fc Tag (2)
마커
Unconjugated (3)Biotin-labeled (1)

제품 번호	종	발현 시스템	제품 설명
HOT SG7-H5225	Human	HEK293	Human Siglec-7 / CD328 Protein, His Tag (MALS verified)
HOT SG7-H82E7	Human	HEK293	Biotinylated Human Siglec-7 / CD328 Protein, His,Avitag™ (MALS & SPR verified)
HOT SI7-H5257	Human	HEK293	Human Siglec-7 / CD328 Protein, Fc (L118A, G120A, E201A) Tag, low Endotoxin (MALS verified)
SI7-H5258	Human	HEK293	Human Siglec-7 / CD328 Protein, Fc (L117A, L118A) Tag, low Endotoxin (MALS verified)

총 수량4

Siglec-7분자 배경

Siglec-7 is a member of the human CD33‐related Siglec receptor. The extracellular region of Siglec‐7 is characterized by an N‐terminal V‐set Ig domain that can bind sialic acid and two C2‐set Ig domains. The cytoplasmic tail of Siglec‐7 has one immune‐receptor tyrosine‐based inhibitory motif (ITIM) and one ITIM‐like motif. Siglec-7 is considered as a sialic acid-dependent immunoreceptor with inhibitory potential and expressed predominantly on human NK cells, monocytes and a small subset of CD8+ T cells.