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Siglec-6

Siglec-6

Siglec-6 분자 정보

Molecule Name
Sialic acid-binding Ig-like lectin 6
분자 별명
SIGLEC6,CD327,CD33L,CD33L1,OBBP1,OB-BP1,CDw327
Drug Development Progress
임상 약물 수2
시판 약물 수0
최고 연구 개발 단계Phase 2 Clinical
표적 별명
CD33 antigen-like 1，CDw327，Obesity-binding protein 1 (OB-BP1)，OBBP1，CD33L，CD33L1，CD327
분자 배경
Sialic acid-binding Ig-like lectin 6 (SIGLEC6) is also known as CD antigen CD327, CD33 antigen-like 1 (CD33L or CD33L1), Obesity-binding protein 1 (OB-BP1). SIGLEC6 belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family, which contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. SIGLEC6 mediates sialic-acid dependent binding to cells. SIGLEC6 binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

Siglec-6 제품 목록

Species
  • Human（1）
Tag
  • Fc Tag（1）
Host
  • HEK293（1）
Conjugate
  • Unconjugated（1）
Grade
  • RUO（1）
Low Endotoxin
  • Yes（1）
분자Cat. No.Product Name종Host구조순도Activity규격 및 가격
Siglec-6
SI6-H5256
Human Siglec-6 / CD327 Protein, Fc Tag, low endotoxin
Human
HEK293
SDS-PAGE
ELISA

$310.00

100ug
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임상 약물 정보

영어 이름연구 코드연구 개발 단계회사적응증임상 시험
anti-siglec-6 CAR-T cell therapy(Xuzhou Medical University)Phase 2 ClinicalXuzhou Medical University (Xzmu)
Leukemia, Myeloid, Acute
상세
AK-006AK006Phase 1 ClinicalAllakos Inc
Chronic Urticaria; Inflammation
상세
Customer Reviews
  • C***u2022-06-25
    Human Siglec-6 / CD327 Protein, Fc Tag, low endotoxin
    The item was expedited very quickly which worked out with our timeline. We are in the process of using the Siglec-6 protein in one of our in-vivo study for immunization. The material itself did not dissolve in complete freund's adjuvant but it was easily made into a fine suspension with the help of some PBS. Overall, I would say the material is easy to work with and the Acro is quick at responding if we have any issues.