언어 선택

Siglec-10

Siglec-10 분자 정보

영어 이름	Sialic acid-binding Ig-like lectin 10	시판 약물 수	0
임상 약물 수	3	표적 별명	UNQ477/PRO940，SIGLEC10，Sialic Acid Binding Ig Like Lectin 10，Sialic Acid Binding Ig-Like Lectin 10 Ig-Like Lectin 7，Siglec-Like Protein 2，Siglec-Like Gene 2，SLG2，Sialic Acid-Binding Ig-Like Lectin 10，Sialic Acid Binding Ig-Like Lectin 10，Siglec-10，PRO940，MGC126774
최고 연구 개발 단계	Phase 3 Clinical

영어 이름	Sialic acid-binding Ig-like lectin 10
표적 별명	UNQ477/PRO940，SIGLEC10，Sialic Acid Binding Ig Like Lectin 10，Sialic Acid Binding Ig-Like Lectin 10 Ig-Like Lectin 7，Siglec-Like Protein 2，Siglec-Like Gene 2，SLG2，Sialic Acid-Binding Ig-Like Lectin 10，Sialic Acid Binding Ig-Like Lectin 10，Siglec-10，PRO940，MGC126774
시판 약물 수	0
임상 약물 수	3
최고 연구 개발 단계	Phase 3 Clinical

Siglec-10 제품 목록

속성
Protein (10)
제품 라이브러리
온라인 (10)
종
Human (7)Mouse (1)Cynomolgus (2)
태그
Mouse IgG Fc Tag (1)Fc Tag (2)His Tag (4)Fc Tag & Avi Tag (1)His Tag & Avi Tag (2)
마커
Unconjugated (6)Biotin-labeled (3)PE Labeled (1)

제품 번호	종	발현 시스템	제품 설명
HOT SI0-H5253	Human	HEK293	Human Siglec-10 Protein, Fc Tag, low endotoxin
HOT SI0-H525b	Human	HEK293	Human Siglec-10 Protein, Mouse IgG2a Fc Tag, low endotoxin (MALS verified)
HOT SI0-H52H9	Human	HEK293	Human Siglec-10 Protein, His Tag (MALS verified)
HOT SI0-H82E3	Human	HEK293	Biotinylated Human Siglec-10 Protein, His,Avitag™ (MALS verified)
SI0-H5255	Human	HEK293	Human Siglec-10 Protein, Fc (L118A, G120A, E201A) Tag
SI0-H82F6	Human	HEK293	Biotinylated Human Siglec-10 Protein, Fc,Avitag™ (MALS verified)
SI0-HP2E5	Human	HEK293	PE-Labeled Human Siglec-10 Protein, His Tag (recommended for neutralizing assay) (Site-specific conjugation)
SI0-M52H7	Mouse	HEK293	Mouse Siglec-10 Protein, His Tag
SI0-C52H5	Cynomolgus	HEK293	Cynomolgus Siglec-10 Protein, His Tag (MALS verified)
SI0-C82E5	Cynomolgus	HEK293	Biotinylated Cynomolgus Siglec-10 Protein, His,Avitag™ (MALS verified)

총 수량10

Siglec-10분자 배경

The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.

Siglec-10분자 별명

SIGLEC10,MGC126774,PRO940,Siglec10,SLG2

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Efprezimod alfa	CD24-Fc; HAS-CD24; CD24-Fc-IgG; MK-7110; MK7110	Phase 3 Clinical	Oncoimmune Inc	Coronavirus Disease 2019 (COVID-19); Dyslipidemias; Graft vs Host Disease; Hematopoietic stem cell transplantation (HSCT); HIV Infections; Leukemia; Leukemia, Myeloid, Acute; Melanoma; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Solid tumours	상세
EXO-CD24		Phase 2 Clinical	Nano24med, Tel-Aviv Sourasky Medical Center	Coronavirus Disease 2019 (COVID-19); Respiratory Distress Syndrome, Adult	상세
ONC-841	ONC-841	Phase 1 Clinical	AcroImmune Group	Alzheimer Disease; Neoplasms; Solid tumours	상세

제품 리뷰

V***w2023-03-17
0사람들이 좋아합니다
Human Siglec-10 Protein, His Tag (MALS verified)
The timely fashion that this protein was delivered has helped us greatly. Knowing how reliable and effective Acro Biosystems is with their product delivery is refreshing. Having access to a quick vendor has helped push along studies. The user interface and accessibility of Acro’s website makes it easy to find exactly what we need when we need it. Definitely will continue to purchase from Acro.
A***r2022-10-20
0사람들이 좋아합니다
Human Siglec-10 Protein, His Tag (MALS verified)
We have been using this Human Siglec-10 Protein, His Tag as a capture for an electrochemiluminescent immunoassay. The performance of the assay was very consistent; the background was low and signal-to-noise ratio was very good, so we were able to get great sensitivity. We’ve ordered from ACRO Biosystems several times for this assay and every time shipments are very consistent and timely, and the reagent is always in stock. They are also very responsive whenever we have product questions or documentation questions regarding certain lots.
C***e2022-09-23
0사람들이 좋아합니다
Human Siglec-10 Protein, His Tag (MALS verified)
Service with Acro and their customer support is as quick as they are helpful. Product was needed as soon as possible for a study and they helped us out in getting the product shipped out and delivered us within 2 days of purchasing. Customer support personal are as friendly as they are insightful. Never have they disappointed when purchasing any of their products.