SIGIRR
SIGIRR 제품 목록
- 속성
Protein (1)
- 제품 라이브러리
온라인 (1)
- 종
Human (1)
- 태그
Fc Tag (1)
- 마커
Unconjugated (1)
| 제품 번호 | 종 | 발현 시스템 | 제품 설명 | 단백질 구조 | 순도 | 특성 |
|---|---|---|---|---|---|---|
 Human | HEK293 | Human SIGIRR Protein, Fc Tag (MALS verified) |  |  |
총 수량1
- 1
SIGIRR분자 배경
Single immunoglobulin IL-1-related receptor (SIGIRR), which is also known as Toll/interleukin-1 receptor 8, is a member of the interleukin-1 receptor (IL-1R) family. SIGIRR acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.
- 제품 목록