Serpin F1

Serpin F1 분자 정보

영어 이름Pigment epithelium-derived factor시판 약물 수0
임상 약물 수2표적 별명Cell proliferation-inducing gene 35 protein,EPC-1,Serpin Family F Member 1,Proliferation-Inducing Protein 35,OI12,Serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1,PIG35,Serine (Or Cysteine) Proteinase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1,OI6,Testis Tissue Sperm-Binding Protein Li 70n,SERPINF1,Serpin F1
최고 연구 개발 단계Phase 3 Clinical
영어 이름Pigment epithelium-derived factor
표적 별명Cell proliferation-inducing gene 35 protein,EPC-1,Serpin Family F Member 1,Proliferation-Inducing Protein 35,OI12,Serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1,PIG35,Serine (Or Cysteine) Proteinase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1,OI6,Testis Tissue Sperm-Binding Protein Li 70n,SERPINF1,Serpin F1
시판 약물 수0
임상 약물 수2
최고 연구 개발 단계Phase 3 Clinical

Serpin F1 제품 목록

  • 속성

    Protein (1)

  • 제품 라이브러리

    온라인 (1)

  • Human (1)

  • 태그

    His Tag (1)

  • 마커

    Unconjugated (1)

제품 번호발현 시스템제품 설명단백질 구조순도특성
SE1-H5221
Human
HEK293
Human Serpin F1 / PEDF Protein, His Tag
총 수량1
  • 1

Serpin F1분자 배경

erpin F1 (SERPINF1) is also known as Pigment epithelium-derived factor (PEDF), Cell proliferation-inducing gene 35 protein (PIG35). Serpin F1 belongs to the serpin family. Serpin F1 is expressed in quiescent cells. PEDF has a variety of functions including antiangiogenic, antitumorigenic, and neurotrophic properties. Endothelial cell migration is inhibited by SERPINF1/ PEDF. PEDF / SERPINF1 suppresses retinal neovascularization and endothelial cell proliferation. PEDF is also responsible for apoptosis of endothelial cells either through the p38 MAPK pathway or through the FAS/FASL pathway. PEDF also displays neurotrophic functions.

Serpin F1분자 별명

SERPINF1,Serpin F1,PEDF,PIG35,EPC-1

임상 약물 정보

영어 이름연구 코드연구 개발 단계회사적응증임상 시험
BRM-421BRM-421Phase 3 ClinicalBrim Biotechnology Co LtdDry Eye Syndromes; Keratoconjunctivitis Sicca; Xerophthalmia
상세
DVC1-0401DVC1-0401Phase 2 ClinicalId Pharma, Kyushu UniversityRetinitis Pigmentosa
상세
  • 분자 정보
  • 제품 목록
  • 임상 약물 정보
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