언어 선택

PSCA

PSCA 분자 정보

영어 이름	Prostate stem cell antigen	시판 약물 수	0
임상 약물 수	4	표적 별명	Prostate stem cell antigen，UNQ206/PRO232，PSCA，PRO232
최고 연구 개발 단계	Phase 1 Clinical

영어 이름	Prostate stem cell antigen
표적 별명	Prostate stem cell antigen，UNQ206/PRO232，PSCA，PRO232
시판 약물 수	0
임상 약물 수	4
최고 연구 개발 단계	Phase 1 Clinical

PSCA 제품 목록

속성
Protein (5)
제품 라이브러리
온라인 (5)
종
Human (4)Mouse (1)
태그
His Tag (3)His Tag & Avi Tag (2)
마커
Unconjugated (1)Biotin-labeled (2)PE Labeled (1)AF488 Labeled (1)

제품 번호	종	발현 시스템	제품 설명
HOT PSA-H52H6	Human	HEK293	Human PSCA Protein, His Tag
HOT PSA-H82E3	Human	HEK293	Biotinylated Human PSCA Protein, His,Avitag™ (MALS verified)
PSA-HA2H3	Human	HEK293	Alexa Fluor™ 488-Labeled Human PSCA Protein, His Tag (Site-specific conjugation)
PSA-HP2H3	Human	HEK293	PE-Labeled Human PSCA Protein, His Tag (Site-specific conjugation)
PSA-M82Ea	Mouse	HEK293	Biotinylated Mouse PSCA Protein, His,Avitag™, low endotoxin (MALS verified)

총 수량5

PSCA분자 배경

The Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored protein, plays an important role in tumorigenesis. The prostate stem cell antigen (PSCA) gene, which encodes a prostate-specific antigen (PSA), was identified as a gene involved in cell adhesion and proliferation. PSCA may be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro. May act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits nicotine-induced signaling probably implicating alpha-3:beta-2- or alpha-7-containing nAChRs.

PSCA분자 별명

PSCA,UNQ206,PRO232

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Autologous Anti-PSCA-CAR-4-1BB/TCRzeta-CD19t-expressing T-lymphocytes (City of Hope Medical Center)		Phase 1 Clinical	City Of Hope National Medical Center	Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant	상세
124-iodine-labeled PSCA targeting minibody (ImaginAb)		Phase 1 Clinical	University Of California At Los Angeles	Pancreatic Neoplasms; Prostatic Neoplasms; Urinary Bladder Neoplasms	상세
anti-PSMA/anti-PSCA CAR T-cell therapy PD-1 silent (Shanghai Unicar-Therapy Bio-medicine)		Phase 1 Clinical	Shanghai Unicar-Therapy Bio-Medicine Technology Co Ltd	Hormone-Resistant Prostate Neoplasms	상세
MB-104	MB-104; MB-105; MB-104 CS1 CAR; MB-105 PSCA CAR	Phase 1 Clinical	City Of Hope National Medical Center	Glioblastoma; Multiple Myeloma; Pancreatic Neoplasms; Prostatic Neoplasms; Stomach Neoplasms; Urinary Bladder Neoplasms	상세