언어 선택

PDGF R alpha

PDGF R alpha 분자 정보

영어 이름	Platelet-derived growth factor receptor alpha	시판 약물 수	8
임상 약물 수	11	표적 별명	RHEPDGFRA，Platelet-derived growth factor alpha receptor，PDGFRA，Alpha-type platelet-derived growth factor receptor，PDGFR-alpha，CD140a antigen，CD140a，Platelet Derived Growth Factor Receptor Alpha，Platelet-Derived Growth Factor Receptor， Alpha Polypeptide，Platelet-Derived Growth Factor Receptor 2，CD140 Antigen-Like Family Member A，PDGF-R-Alpha，PDGFR-2，PDGFR2，Platelet-Derived Growth Factor Receptor Alpha，Alpha Platelet-Derived Growth Factor Receptor，Receptor， Platelet-Derived Growth Factor alpha，GAS9
최고 연구 개발 단계	Approved

영어 이름	Platelet-derived growth factor receptor alpha
표적 별명	RHEPDGFRA，Platelet-derived growth factor alpha receptor，PDGFRA，Alpha-type platelet-derived growth factor receptor，PDGFR-alpha，CD140a antigen，CD140a，Platelet Derived Growth Factor Receptor Alpha，Platelet-Derived Growth Factor Receptor， Alpha Polypeptide，Platelet-Derived Growth Factor Receptor 2，CD140 Antigen-Like Family Member A，PDGF-R-Alpha，PDGFR-2，PDGFR2，Platelet-Derived Growth Factor Receptor Alpha，Alpha Platelet-Derived Growth Factor Receptor，Receptor， Platelet-Derived Growth Factor alpha，GAS9
시판 약물 수	8
임상 약물 수	11
최고 연구 개발 단계	Approved

PDGF R alpha 제품 목록

속성
Protein (1)
제품 라이브러리
온라인 (1)
종
Human (1)
태그
His Tag (1)
마커
Unconjugated (1)

제품 번호	종	발현 시스템	제품 설명	단백질 구조	순도	특성
PDA-H52H7	Human	HEK293	Human PDGF R alpha / PDGFRA Protein, His Tag

총 수량1

제품 문의

PDGF R alpha분자 배경

PDGFRA(platelet-derived growth factor receptor A), also termed PDGFRα(platelet-derived growth factor receptor α), is a receptor located on the surface of a wide range of cell types. This receptor binds to certain isoforms of platelet-derived growth factors (PDGFs) and thereby becomes active in stimulating cell signaling pathways that elicit responses such as cellular growth and differentiation. The receptor is critical for the development of certain tissues and organs during embryogenesis and for the maintenance of these tissues and organs, particularly hematologic tissues, throughout life. Mutations in the gene which codes for PDGFRA, are associated with an array of clinically significant neoplasms.

PDGF R alpha분자 별명

PDGFRA,CD140A,PDGFR2,RHEPDGFRA,MGC74795

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Seralutinib	PK-10571; GB-002	Phase 3 Clinical	Gilead Sciences Inc	Pulmonary Arterial Hypertension	상세
Crenolanib Besylate	CP-868596-26; IND-112201; CP-868596; ARO-002; ARO-002-26; CP-868; 596-26; CP-868; 596	Phase 3 Clinical	Pfizer Inc	Gastrointestinal Stromal Tumors; Glioma; Leukemia, Myeloid, Acute	상세
AZD-3229	NB-003; NB003; AZD-3229; AZD3229	Phase 3 Clinical	Astrazeneca Turkey	Gastrointestinal Stromal Tumors; Influenza B virus infection; Solid tumours	상세
Lucitanib	S-80881; AL-3810; CO-3810; E-3810; S-80881-2	Phase 2 Clinical	Advenchen Laboratories Nanjing Ltd	Breast Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Genital Neoplasms, Female; Lung Neoplasms; Metastatic breast cancer; Nasopharyngeal Carcinoma; Small Cell Lung Carcinoma; Solid tumours; Stomach Neoplasms; Thymus Neoplasms	상세
Inhaled Nintedanib – dry powder (Avalyn Pharma)	AP02; AP 02 DP; AP-02; AP02-DP	Phase 2 Clinical	Avalyn Pharma Inc	Idiopathic Pulmonary Fibrosis; Lung Diseases, Interstitial; Pulmonary Fibrosis; Respiratory Tract Diseases	상세
Nintedanib Esylate Inhalation Powder(Cspc)		Phase 1 Clinical	Cspc-Nbp Pharmaceutical Co Ltd	Idiopathic Pulmonary Fibrosis; Pulmonary Fibrosis	상세
MNKD-201	MNKD-201; MKND-201	Phase 1 Clinical	MannKind Corp	Idiopathic Pulmonary Fibrosis	상세
TLX-300	TLX-300-CDx; TLX-300; TLX300	Phase 1 Clinical	Eli Lilly And Company	Neoplasms; Sarcoma; Soft Tissue Neoplasms	상세
T-1301	T-1301; DBPR-216; BPR-1J481; BPR1J481	Phase 1 Clinical	Taivex Therapeutics Corp	Lymphoma; Solid tumours	상세
ICP-033	ICP-033	Phase 1 Clinical	Beijing Innocare Pharma Tech Co Ltd	Solid tumours	상세
Luxeptinib	CG026806; CG-806; CG’806; CG-026806	Phase 1 Clinical	Crystalgenomics Inc	Hematologic Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Myelodysplastic Syndromes	상세

시판 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	가장 빠른 브랜드 이름	가장 빠른 승인 국가	가장 빠른 적응증	가장 빠른 승인 회사	가장 빠른 승인 날짜	적응증	임상 시험
Lenvatinib Mesilate	E-7080; MK-7902; ER-203492-00	Approved	Eisai Co Ltd	Kisplyx, Lenvima, Lenvima/Kisplyx, 乐卫玛	United States	Thyroid Neoplasms	Eisai Inc	2015-02-13	Adenocarcinoma; Adenocarcinoma of Lung; Adenocarcinoma, Follicular; Biliary Tract Neoplasms; Breast Neoplasms; Carcinoma, Adenoid Cystic; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Cholangiocarcinoma; Endometrial Neoplasms; Esophageal Neoplasms; Gastrointestinal Stromal Tumors; Glioma; Hepatic Insufficiency; Liver Diseases; Liver Neoplasms; Lymphoma; Melanoma; Neoplasm Metastasis; Neoplasms; Neuroendocrine Tumors; Osteosarcoma; Ovarian Neoplasms; Paraganglioma; Pheochromocytoma; Renal Insufficiency; Solid tumours; Stomach Neoplasms; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Uterine Cervical Neoplasms	상세
Regorafenib	DAST; BAY-73-4506	Approved	Bayer AG	Stivarga, Resihance	United States	Colorectal Neoplasms	Bayer Healthcare Pharmaceuticals Inc	2012-09-27	Adenocarcinoma; Adenoma; Bile Duct Neoplasms; Carcinoma, Adenoid Cystic; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Ovarian Epithelial; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Colonic Neoplasms; Colorectal Neoplasms; Esophageal adenocarcinoma; Esophageal Neoplasms; Fallopian Tube Neoplasms; Gastrinoma; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Glucagonoma; Hemangiosarcoma; Insulinoma; Leukemia, Myeloid, Acute; Liver Neoplasms; Lung Neoplasms; Melanoma; Meningioma; Neoplasm Metastasis; Neoplasms; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Rectal Neoplasms; Sarcoma; Sarcoma, Ewing; Solid tumours; Somatostatinoma; Stomach Neoplasms; Thymoma; Thyroid Neoplasms	상세
Olaratumab	IMC-3G3; LY-3012207	Approved	Eli Lilly And Company	Lartruvo	United States	Sarcoma	Eli Lilly And Company	2016-10-19	Carcinoma, Non-Small-Cell Lung; Dermatofibrosarcoma; Fibrosarcoma; Gastrointestinal Stromal Tumors; Hemangiosarcoma; Leiomyosarcoma; Liposarcoma; Neoplasm Metastasis; Neoplasms; Neurofibrosarcoma; Ovarian Neoplasms; Prostatic Neoplasms; Sarcoma; Sarcoma, Synovial; Solid tumours	상세
Nintedanib Esylate	BIBF-1120	Approved	C.H. Boehringer Sohn Ag & Co. Kg	Ofev, Vargatef	United States	Idiopathic Pulmonary Fibrosis	Boehringer Ingelheim International Gmbh	2014-10-15	Adenocarcinoma, Clear Cell; Appendiceal Neoplasms; Asbestosis; Astrocytoma; Breast Neoplasms; Carcinoid Tumor; Carcinoma, Endometrioid; Carcinoma, Hepatocellular; Carcinoma, Neuroendocrine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Colonic Neoplasms; Colorectal Neoplasms; Endometrial Neoplasms; Endometrial Stromal Tumors; Esophageal Neoplasms; Fallopian Tube Neoplasms; Genital Neoplasms, Female; Glioblastoma; Gliosarcoma; Hepatic Insufficiency; Idiopathic Pulmonary Fibrosis; Leukemia, Myeloid, Acute; Lung Diseases, Interstitial; Mesothelioma; Multiple Myeloma; Neoplasms; Oligodendroglioma; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms; Pulmonary Fibrosis; Radiation Pneumonitis; Rejection of lung transplantation; Sarcoma; Scleroderma, Systemic; Silicosis; Small Cell Lung Carcinoma; Solid tumours; systemic sclerosis-associated interstitial lung disease; Telangiectasia, Hereditary Hemorrhagic; Uterine Neoplasms	상세
Avapritinib	BLU-285; CS-3007	Approved	Blueprint Medicines Corp	Ayvakit, Ayvakyt, 泰吉华, Taijihua	United States	Gastrointestinal Stromal Tumors	Blueprint Medicines Corp	2020-01-09	Adenocarcinoma; Breast Neoplasms; Central Nervous System Neoplasms; Colorectal Neoplasms; Esophageal Neoplasms; Gastrointestinal Stromal Tumors; Hematologic Neoplasms; Leukemia, Mast-Cell; Lung Neoplasms; Mastocytosis, Systemic; Melanoma; Sarcoma; Solid tumours; Stomach Neoplasms	상세
Ripretinib	DCC-2618	Approved	Deciphera Pharmaceuticals	Qinlock, 擎乐	United States	Gastrointestinal Stromal Tumors	Deciphera Pharmaceuticals Llc	2020-05-15	Gastrointestinal Stromal Tumors; Mastocytosis, Systemic; Neoplasms	상세
Sunitinib Malate	PNU-290940AD; PHA-290940AD; SCAI-003; SU-010398; SU-11248; GB-102; PHA-290940; PNU-290940; SU-011248-L-malate salt	Approved	Pfizer Inc	Sutent, 索坦	United States	Gastrointestinal Stromal Tumors; Carcinoma, Renal Cell	Cppi Cv	2006-01-26	Abdominal Neoplasms; Adenocarcinoma; Adenocarcinoma, Follicular; Adenoma, Islet Cell; Adrenocortical Carcinoma; AIDS-Related Complex; Amyloidosis; Angioimmunoblastic T-cell Lymphoma; Astrocytoma; Barrett Esophagus; Brain metastases; Brain Neoplasms; Breast Neoplasms; Burkitt Lymphoma; Carcinoma; Carcinoma, Acinar Cell; Carcinoma, Adenoid Cystic; Carcinoma, Adenosquamous; Carcinoma, Embryonal; Carcinoma, Hepatocellular; Carcinoma, Islet Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Ovarian Epithelial; Carcinoma, Papillary; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Central Nervous System Neoplasms; Choriocarcinoma; Chronic eosinophilic leukemia (CEL); Cognition Disorders; Colorectal Neoplasms; Diabetic macular oedema; Endodermal Sinus Tumor; Endometrial Neoplasms; Ependymoma; Esophageal Neoplasms; Fallopian Tube Neoplasms; Fibromatosis, Aggressive; Fibrosarcoma; Gastrointestinal Stromal Tumors; Germinoma; Glioblastoma; Glioma; Gliosarcoma; Head and Neck Neoplasms; Hemangi	상세
Pazopanib Hydrochloride	GSK-786034; GW-786034B; SB-786034; GW-786034	Approved	Glaxosmithkline Plc, Novartis Pharma Ag	维全特, Armala, Votrient, Patorma	United States	Carcinoma, Renal Cell; Sarcoma	Novartis Pharma Ag	2009-10-19	Adenocarcinoma, Follicular; Brain Neoplasms; Breast Neoplasms; Breast Neoplasms, Male; Carcinoma, Embryonal; Carcinoma, Hepatocellular; Carcinoma, Neuroendocrine; Carcinoma, Non-Small-Cell Lung; Carcinoma, Ovarian Epithelial; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Central Nervous System Neoplasms; Chondrosarcoma; Chondrosarcoma, Extraskeletal Myxoid; Choriocarcinoma; Colorectal Neoplasms; Dermatofibrosarcoma; Endodermal Sinus Tumor; Epistaxis; Fallopian Tube Neoplasms; Fibromatosis, Aggressive; Gastrinoma; Gastroenteropancreatic neuroendocrine tumor; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Genital Neoplasms, Female; Germinoma; Glioblastoma; Glioma; Gliosarcoma; Glucagonoma; Hemangiosarcoma; Herpes Genitalis; Herpes Simplex; HIV Infections; Hormone-Resistant Prostate Neoplasms; Insulinoma; Leiomyosarcoma; Leukemia, Myeloid, Acute; Liposarcoma; Lung Neoplasms; Lymphoma; Macular Degeneration; Medullary thyroid cancer (MTC); Melanoma; Mesothelioma; Multiple Endocrine Neoplasia T	상세