언어 선택

PD-L2

PD-L2 분자 정보

영어 이름	Programmed death-ligand 2	시판 약물 수	0
임상 약물 수	3	표적 별명	PDCD1LG2，PDL2，Programmed death ligand 2，CD273，Butyrophilin B7-DC，PD-1 ligand 2，B7-DC，BA574F11.2，PDCD1L2，CD273 Antigen，B7DC，Btdc，B7 Dendritic Cell Molecule，PD-1-Ligand 2，PDCD1 ligand 2，Programmed cell death 1 ligand 2
최고 연구 개발 단계	Phase 3 Clinical

영어 이름	Programmed death-ligand 2
표적 별명	PDCD1LG2，PDL2，Programmed death ligand 2，CD273，Butyrophilin B7-DC，PD-1 ligand 2，B7-DC，BA574F11.2，PDCD1L2，CD273 Antigen，B7DC，Btdc，B7 Dendritic Cell Molecule，PD-1-Ligand 2，PDCD1 ligand 2，Programmed cell death 1 ligand 2
시판 약물 수	0
임상 약물 수	3
최고 연구 개발 단계	Phase 3 Clinical

PD-L2 제품 목록

속성
Protein (8)
제품 라이브러리
온라인 (8)
종
Human (5)Mouse (3)
태그
His Tag (2)Fc Tag (2)Mouse IgG Fc Tag (1)His Tag & Avi Tag (2)Fc Tag & Avi Tag (1)
마커
Unconjugated (5)Biotin-labeled (3)

제품 번호	종	발현 시스템	제품 설명
HOT PD2-H5220	Human	HEK293	Human PD-L2 / B7-DC Protein, His Tag, low endotoxin (SPR verified)
HOT PD2-H82E8	Human	HEK293	Biotinylated Human PD-L2 / B7-DC Protein, Avitag™,His Tag (recommended for biopanning)
HOT PD2-H82F6	Human	HEK293	Biotinylated Human PD-L2 / B7-DC Protein, Fc,Avitag™ (MALS verified)
HOT PD2-M52E3	Mouse	HEK293	Mouse PD-L2 / B7-DC Protein, His Tag (MALS verified)
HOT PD2-M82E3	Mouse	HEK293	Biotinylated Mouse PD-L2 / B7-DC Protein, His,Avitag™ (MALS verified)
PD2-H5251	Human	HEK293	Human PD-L2 / B7-DC Protein, Fc Tag, low endotoxin (MALS & BLI verified)
PD2-H52A5	Human	HEK293	Human PD-L2 / B7-DC Protein, Mouse IgG1 Fc Tag
PD2-M5254	Mouse	HEK293	Mouse PD-L2 / B7-DC Protein, Fc Tag

총 수량8

PD-L2분자 배경

Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

PD-L2분자 별명

PDL2,PD-L2,Butyrophilin B7-DC,CD273,PDCD1 ligand 2,PDCD1L2,PDCD1LG2

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
CA-170	CA-170; AUPM-170	Phase 3 Clinical	Aurigene	Carcinoma, Non-Small-Cell Lung; Neoplasms; Solid tumours	상세
IMGS-001	IMGS-001	Phase 1 Clinical	The University Of Texas MD Anderson Cancer Center	Colorectal Neoplasms; Neoplasms; Prostatic Neoplasms; Solid tumours; Triple Negative Breast Neoplasms	상세
68Ga-Mirc415		Clinical	Beijing Cancer Hospital	Lung Neoplasms	상세

제품 리뷰

1***32019-10-11
0사람들이 좋아합니다
Human PD-L2 / B7-DC Protein, His Tag, low endotoxin (SPR verified)
ACROBiosystem's proteins have high purity. They totally meet our requirements. Most importantly, repeatability among batches is very good, and the quality control is great. Thank you!
1***22019-10-12
1사람들이 좋아합니다
Human PD-L2 / B7-DC Protein, Fc Tag, low endotoxin (MALS & BLI verified)
I purchased the PD-L2 protein for ELISA related experiments. Coating the protein into a well plate, and then adding antibody molecules to incubate with biotin-PD1. I could obtain good stable and repeatable data.