언어 선택

P-Selectin

P-Selectin 분자 정보

영어 이름	P-selectin	시판 약물 수	1
임상 약물 수	1	표적 별명	Platelet Activation Dependent Granule-External Membrane Protein，Granule Membrane Protein 140kDa，PADGEM，GRMP，Selectin P (Granule Membrane Protein 140kD， Antigen CD62)，Platelet Alpha-Granule Membrane Protein，Granulocyte Membrane Protein，CD62P Antigen，Antigen CD62，P-Selectin，GMP140，CD62P，CD62，PSEL，LECAM3，CD62 antigen-like family member P，GMRP，GMP-140，Granule membrane protein 140，SELP，Selectin P，Selectin P (Granule Membrane Protein 140kDa， Antigen CD62)，Leukocyte-Endothelial Cell Adhesion Molecule 3
최고 연구 개발 단계	Approved

영어 이름	P-selectin
표적 별명	Platelet Activation Dependent Granule-External Membrane Protein，Granule Membrane Protein 140kDa，PADGEM，GRMP，Selectin P (Granule Membrane Protein 140kD， Antigen CD62)，Platelet Alpha-Granule Membrane Protein，Granulocyte Membrane Protein，CD62P Antigen，Antigen CD62，P-Selectin，GMP140，CD62P，CD62，PSEL，LECAM3，CD62 antigen-like family member P，GMRP，GMP-140，Granule membrane protein 140，SELP，Selectin P，Selectin P (Granule Membrane Protein 140kDa， Antigen CD62)，Leukocyte-Endothelial Cell Adhesion Molecule 3
시판 약물 수	1
임상 약물 수	1
최고 연구 개발 단계	Approved

P-Selectin 제품 목록

속성
Protein (2)
제품 라이브러리
온라인 (2)
종
Human (2)
태그
His Tag (1)Fc Tag (1)
마커
Unconjugated (2)

제품 번호	종	발현 시스템	제품 설명	단백질 구조	순도	특성
SEP-H5255	Human	HEK293	Human P-Selectin / CD62P Protein, Fc Tag
SEP-H52E4	Human	HEK293	Human P-Selectin / CD62P Protein, His Tag

총 수량2

제품 문의

P-Selectin분자 배경

P-selectin (SELP) is also known as CD62 antigen-like family member P, granule membrane protein 140 (GMP-140), leukocyte-endothelial cell adhesion molecule 3 (LECAM3) and platelet activation dependent granule-external membrane protein (PADGEM). SELP functions as a cell adhesion molecule (CAM) on the surfaces of activated endothelial cells, which line the inner surface of blood vessels, and activated platelets. In unactivated endothelial cells, it is stored in granules called Weibel-Palade bodies. In unactivated platelets SELP is stored in α-granules. The primary ligand for SELP is P-selectin glycoprotein ligand-1 (PSGL-1) which is expressed on almost all leukocytes, although P-selectin also binds to heparan sulfate and fucoidan. Furthermore, SELP has a functional role in metastasis of tumor similar to E-selectin, which can help cancer cells invade into bloodstream for metastasis and provided locally with multiple growth factors respectively.

P-Selectin분자 별명

P-Selectin,CD62P,SELP,GMP-140

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Inclacumab	DSM-ACC-2641; RO 4905417; LC1004-002; DSM ACC2641; RG-1512; LC-1004-002; R-1512; PF-07940370; RO-4905417	Phase 3 Clinical	F. Hoffmann-La Roche Ltd, Genmab A/S	Anemia, Sickle Cell; Graft Occlusion, Vascular; Myocardial Infarction; Pain; Peripheral Arterial Disease	상세

시판 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	가장 빠른 브랜드 이름	가장 빠른 승인 국가	가장 빠른 적응증	가장 빠른 승인 회사	가장 빠른 승인 날짜	적응증	임상 시험
Crizanlizumab	Sel-G-1; SEG-101; SEG101; Sel-G1	Approved	Selexys Pharmaceuticals Corp	Adakveo, Ryverna	United States	Anemia, Sickle Cell	Novartis Pharmaceuticals Corp	2019-11-15	Anemia, Sickle Cell; Coronavirus Disease 2019 (COVID-19); Leukoencephalopathies; Priapism; Primary Myelofibrosis	상세

제품 리뷰

V***u2023-07-13
2사람들이 좋아합니다
Human P-Selectin / CD62P Protein, His Tag
AcroBio is our go to vendor, for our growing biotechnology start up. The customer service at acro bio is excellent, products have never failed in our labs. The specific product we got is the Human P-selectin/CD62P Protein His Tag which our lab has gotten multiple times and has not failed us. Thank you AcroBio for your amazing services, we appreciate you!