언어 선택

Osteopontin

Osteopontin 분자 정보

영어 이름	Osteopontin	시판 약물 수	0
임상 약물 수	0	표적 별명	Secreted Phosphoprotein 1 (Osteopontin， Bone Sialoprotein I， Early T-Lymphocyte Activation 1)，Osteopontin/Immunoglobulin Alpha 1 Heavy Chain Constant Region Fusion Protein，Secreted Phosphoprotein 1 Variant 6，SPP1/CALPHA1 Fusion，ETA-1，BSPI，SPP-1，Bone sialoprotein 1，BNSP，Urinary stone protein，PSEC0156，OPN，Uropontin，SPP1，Secreted Phosphoprotein 1，Early T-Lymphocyte Activation 1，Nephropontin，Osteopontin，Bone Sialoprotein I
최고 연구 개발 단계	Preclinical

영어 이름	Osteopontin
표적 별명	Secreted Phosphoprotein 1 (Osteopontin， Bone Sialoprotein I， Early T-Lymphocyte Activation 1)，Osteopontin/Immunoglobulin Alpha 1 Heavy Chain Constant Region Fusion Protein，Secreted Phosphoprotein 1 Variant 6，SPP1/CALPHA1 Fusion，ETA-1，BSPI，SPP-1，Bone sialoprotein 1，BNSP，Urinary stone protein，PSEC0156，OPN，Uropontin，SPP1，Secreted Phosphoprotein 1，Early T-Lymphocyte Activation 1，Nephropontin，Osteopontin，Bone Sialoprotein I
시판 약물 수	0
임상 약물 수	0
최고 연구 개발 단계	Preclinical

Osteopontin 제품 목록

속성
Protein (3)
제품 라이브러리
온라인 (3)
종
Human (2)Mouse (1)
태그
His Tag (1)His Tag & Avi Tag (2)
마커
Unconjugated (1)Biotin-labeled (2)

제품 번호	종	발현 시스템	제품 설명
OPN-H5227	Human	HEK293	Human Osteopontin (OPN) Protein, His Tag, premium grade
OPN-H82E8	Human	HEK293	Biotinylated Human Osteopontin (OPN) Protein, His,Avitag™
OPN-M82E8	Mouse	HEK293	Biotinylated Mouse Osteopontin (OPN) Protein, His,Avitag™

총 수량3

Osteopontin분자 배경

Osteopontin (OPN) is also known as Secreted phosphoprotein 1 (SPP1), Bone sialoprotein 1, Nephropontin, Urinary stone protein, Uropontin, BNSP, which belongs to the osteopontin family. OPN / SPP1 is a highly negatively charged, extracellular matrix protein that lacks an extensive secondary structure. Full length OPN (OPN-FL) can be modified by thrombin cleavage, which exposes a cryptic sequence, SVVYGLR on the cleaved form of the protein known as OPN-R. Osteopontin / SPP-1 is biosynthesized by a variety of tissue types. OPN is the ligand for integrin alpha-V/beta-3. OPN / SPP1 binds tightly to hydroxyapatite and appears to form an integral part of the mineralized matrix. OPN / SPP1 probably important to cell-matrix interaction. OPN / SPP1 acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity.