언어 선택

Osteoactivin

Osteoactivin 분자 정보

영어 이름	Transmembrane glycoprotein NMB	시판 약물 수	0
임상 약물 수	2	표적 별명	Transmembrane Glycoprotein，HGFIN，Transmembrane glycoprotein NMB，Hematopoietic growth factor inducible neurokinin-1 type，GPNMB，Glycoprotein Nmb，Hematopoietic Growth Factor Inducible Neurokinin-1，Glycoprotein Nonmetastatic Melanoma Protein B，Transmembrane Glycoprotein HGFIN，Glycoprotein (Transmembrane) Nmb，Glycoprotein Nmb-Like Protein，Osteoactivin，PLCA3，NMB，UNQ1725/PRO9925
최고 연구 개발 단계	Phase 2 Clinical

영어 이름	Transmembrane glycoprotein NMB
표적 별명	Transmembrane Glycoprotein，HGFIN，Transmembrane glycoprotein NMB，Hematopoietic growth factor inducible neurokinin-1 type，GPNMB，Glycoprotein Nmb，Hematopoietic Growth Factor Inducible Neurokinin-1，Glycoprotein Nonmetastatic Melanoma Protein B，Transmembrane Glycoprotein HGFIN，Glycoprotein (Transmembrane) Nmb，Glycoprotein Nmb-Like Protein，Osteoactivin，PLCA3，NMB，UNQ1725/PRO9925
시판 약물 수	0
임상 약물 수	2
최고 연구 개발 단계	Phase 2 Clinical

Osteoactivin 제품 목록

속성
Protein (1)
제품 라이브러리
온라인 (1)
종
Human (1)
태그
His Tag (1)
마커
Unconjugated (1)

제품 번호	종	발현 시스템	제품 설명	단백질 구조	순도	특성
GPB-H5229	Human	HEK293	Human Osteoactivin / GPNMB Protein, His Tag, low endotoxin

총 수량1

Osteoactivin분자 배경

Transmembrane glycoprotein NMB (GPNMB) is also known as Transmembrane glycoprotein HGFIN, DC-HIL and Osteoactivin (OA), which belongs to the PMEL/NMB family. GPNMB contains one PKD domain. GPNMB is a transmembrane glycoprotein that is up-regulated in various cancer cells, including in glioblastoma multiforme and is expressed in many melanoma cells, as well as in tissue macrophages. GPNMB protein acts as a downstream mediator of BMP-2 effects on osteoblast differentiation and function. GPNMB participates in bone mineralization, and functions as a negative regulator of inflammation in macrophages.

Osteoactivin분자 별명

GPNMB,HGFIN,NMB,Osteoactivin

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Glembatumumab vedotin	CR-011; CDX-011; CR-011-ADC; CR011-vcMMAE	Phase 2 Clinical	Celldex Therapeutics	Breast Neoplasms; Carcinoma, Squamous Cell; Melanoma; Osteosarcoma; Skin Melanoma; Solid tumours; Triple Negative Breast Neoplasms; Uveal melanoma	상세
GPNMB-targeting Chimeric Antigen Receptor T-Cell Therapy (AHS Cancer Control Alberta)	GCAR1	Phase 1 Clinical	AHS Cancer Control Alberta	Carcinoma, Renal Cell; Sarcoma; Sarcoma, Alveolar Soft Part; Triple Negative Breast Neoplasms	상세

제품 리뷰

A***c2026-02-27
0사람들이 좋아합니다
Human Osteoactivin / GPNMB Protein, His Tag, low endotoxin
The Human Osteoactivin / GPNMB Protein, His Tag I purchased has been a reliable and useful reagent for interference testing. This reagent was optimal for work in both a PK and ADA assay. There have been no observed lot to lot differences, which is important in my line of work. I would recommend this product.