OSMR

OSMR

OSMR 분자 정보

Molecule Name
Oncostatin-M-specific receptor subunit beta
분자 별명
Oncostatin-M-specific receptor subunit beta,Interleukin-31 receptor subunit beta,IL-31 receptor subunit beta,IL-31R subunit beta,IL-31R-beta,IL-31RB,OSMR,OSMRB
Drug Development Progress
임상 약물 수1
시판 약물 수0
최고 연구 개발 단계Phase 2 Clinical
표적 별명
IL-31R-beta,IL-31RB,Interleukin-31 receptor subunit beta,IL-31 receptor subunit beta,IL-31R subunit beta
분자 배경
Oncostatin-M-specific receptor subunit beta (OSMRβ), also known as Interleukin-31 receptor subunit beta (IL-31RB), is the beta subunit of the type II OSM receptor, which is a heterodimer of gp130 and OSMRβ. OSMRβ associates with the low-affinity OSM·gp130 complex to form a high-affinity heterodimeric receptor that is capable of transducing OSM-specific signaling events.

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임상 약물 정보

영어 이름연구 코드연구 개발 단계회사적응증임상 시험
VixarelimabKPL-716; BIIB-069; RG-6536; RO-7622888Phase 2 ClinicalBiogen Inc
Chronic Urticaria; Colitis, Ulcerative; Lichen Planus; Neurodermatitis; Plaque psoriasis; Prurigo Nodularis; Pruritus
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