ORF8
ORF8 제품 목록
- 속성
Protein (1)
- 제품 라이브러리
온라인 (1)
- 종
SARS-CoV-2 (1)
- 태그
His Tag (1)
- 마커
Unconjugated (1)
| 제품 번호 | 종 | 발현 시스템 | 제품 설명 | 단백질 구조 | 순도 | 특성 |
|---|---|---|---|---|---|---|
SARS-CoV-2 | HEK293 | SARS-CoV-2 ORF8 Protein, His Tag (MALS verified) |  |  |
총 수량1
- 1
ORF8분자 배경
The viral protein encoded by open reading frame 8 (ORF8) of SARS-CoV-2, which shares the least homology with SARS-CoV among all viral proteins, directly interacts with MHC-Ι molecules and mediates their down-regulation. In ORF8-expressing cells, MHC-Ι molecules are selectively targeted for lysosomal degradation via autophagy. Thus, SARS-CoV-2–infected cells are much less sensitive to lysis by cytotoxic T lymphocytes.
- 제품 목록