NKG2C

NKG2C Product List

  • Product Category

    Protein (2)

  • Product Status

    Launched (2)

  • Species

    Human (1)Cynomolgus (1)

  • Tag

    His Tag (2)

  • Conjugate

    Unconjugated (2)

Cat. No.SpeciesHostProduct DescriptionStructurePurityFeature
NKC-H5248
Human
HEK293
Human NKG2C / CD159c Protein, His Tag
NKC-C5247
Cynomolgus
HEK293
Cynomolgus NKG2C / CD159c Protein, His Tag
Total: 2
  • 1

NKG2C Background

Human NKG2C (NK cell Group 2 isoform C; Killer cell lectin-like receptor subfamily C, member 2) is a member of the C-type lectin-like superfamily of proteins. NKG2C plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. The CD94/NKG2C killer lectin-like receptor (KLR) specific for HLA-E is coupled to the KARAP/DAP12 adapter in a subset of NK cells, triggering their effector functions. CD94/NKG2C may operate as an alternative activation pathway for a subset of CD8+ T lymphocytes, triggering their effector functions and proliferation upon specific ligand engagement.
  • Product List
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