언어 선택

NGFR

NGFR 분자 정보

영어 이름	Low affinity neurotrophin receptor p75NTR	시판 약물 수	0
임상 약물 수	3	표적 별명	Gp80-LNGFR，P75NTR，CD271 Antigen，Low-Affinity Nerve Growth Factor Receptor，Tumor Necrosis Factor Receptor Superfamily Member 16，Low Affinity Nerve Growth Factor Receptor，Low Affinity Neurotrophin Receptor P75NTR，Nerve Growth Factor Receptor (TNFR Superfamily， Member 16)，TNFR Superfamily， Member 16，Nerve Growth Factor Receptor，P75 ICD，P75(NTR)，TNFRSF16，CD271
최고 연구 개발 단계	Phase 2 Clinical

영어 이름	Low affinity neurotrophin receptor p75NTR
표적 별명	Gp80-LNGFR，P75NTR，CD271 Antigen，Low-Affinity Nerve Growth Factor Receptor，Tumor Necrosis Factor Receptor Superfamily Member 16，Low Affinity Nerve Growth Factor Receptor，Low Affinity Neurotrophin Receptor P75NTR，Nerve Growth Factor Receptor (TNFR Superfamily， Member 16)，TNFR Superfamily， Member 16，Nerve Growth Factor Receptor，P75 ICD，P75(NTR)，TNFRSF16，CD271
시판 약물 수	0
임상 약물 수	3
최고 연구 개발 단계	Phase 2 Clinical

NGFR 제품 목록

속성
Protein (1)Cell (1)
제품 라이브러리
온라인 (2)
종
Human (2)
태그
Fc Tag (1)- (1)
마커
Unconjugated (1)- (1)

제품 번호	종	발현 시스템	제품 설명	단백질 구조	순도	특성
CHEK-ATP157	Human	HEK293	HEK293/Human NGFR Stable Cell Line
NGR-H5254	Human	HEK293	Human NGFR / TNFRSF16 Protein, Fc Tag (MALS & BLI verified)

총 수량2

NGFR분자 배경

The p75 neurotrophin receptor (p75NTR) was originally identified as a low-affinity receptor for neurotrophins(NGF R).p75NTR is a neurotrophic factor receptor. Neurotrophic factor receptors bind Neurotrophins including Nerve growth factor, Neurotrophin-3, Brain-derived neurotrophic factor, and Neurotrophin-4. All neurotrophins bind to p75NTR. This also includes the immature pro-neurotrophin forms. Neurotrophic factor receptors, including p75NTR, are responsible for ensuring a proper density to target ratio of developing neurons, refining broader maps in development into precise connections. p75NTR is involved in pathways that promote neuronal survival and neuronal death.

NGFR분자 별명

tumor necrosis factor receptor superfamily member 16; CD271; Gp80-LNGFR; member 16 nerve growth factor receptor; p75 ICD; p75 NTR

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
LM11A-31	LM11A-31; LM11A-31-BHS	Phase 2 Clinical	Pharmatrophix Inc	Alzheimer Disease; Supranuclear Palsy, Progressive	상세
Recombinant human nerve growth factor (Xintrum Pharmacouticals)	rh-NGF; ZX1305; ZX-1305; ZX1305E; ZX-1305-E	Phase 2 Clinical	Jiangsu Zhongxin Pharmaceutical Co Ltd	Glaucoma, Open-Angle; Keratitis; Optic Nerve Injuries	상세
Recombinant Human Nerve Growth Factor (Kerun Biopharmaceutical)		Phase 1 Clinical	Chongqing Kerun Biologic Pharmaceutical Development Co Ltd	Keratitis; Xerophthalmia	상세