언어 선택

Mucin-1

Mucin-1 분자 정보

영어 이름	Mucin-1	시판 약물 수	0
임상 약물 수	28	표적 별명	PEM，Medullary Cystic Kidney Disease 1 (Autosomal Dominant)，Tumor Associated Epithelial Mucin，CD227 Antigen，H23 Antigen，MUC-1/SEC，ADMCKD1，Cancer antigen 15-3，Tumor-associated mucin，MUC1-alpha，MUC1-beta，MUC-1/X，MUC1/ZD，Mucin-1，ADMCKD，MCKD1，MAM6，MCKD，MCD，Polymorphic epithelial mucin，PUM，MUC1-NT，Episialin，CD227，MUC1-CT，MUC1，Mucin 1， Cell Surface Associated，Tumor-Associated Epithelial Membrane Antigen，Peanut-Reactive Urinary Mucin，Carcinoma-Associated Mucin，Krebs Von Den Lungen-6，CA 15-3，H23AG，MUC-1，KL-6，PEMT，EMA，Breast carcinoma-associated antigen DF3，Mucin 1， Transmembrane
최고 연구 개발 단계	Phase 2 Clinical

영어 이름	Mucin-1
표적 별명	PEM，Medullary Cystic Kidney Disease 1 (Autosomal Dominant)，Tumor Associated Epithelial Mucin，CD227 Antigen，H23 Antigen，MUC-1/SEC，ADMCKD1，Cancer antigen 15-3，Tumor-associated mucin，MUC1-alpha，MUC1-beta，MUC-1/X，MUC1/ZD，Mucin-1，ADMCKD，MCKD1，MAM6，MCKD，MCD，Polymorphic epithelial mucin，PUM，MUC1-NT，Episialin，CD227，MUC1-CT，MUC1，Mucin 1， Cell Surface Associated，Tumor-Associated Epithelial Membrane Antigen，Peanut-Reactive Urinary Mucin，Carcinoma-Associated Mucin，Krebs Von Den Lungen-6，CA 15-3，H23AG，MUC-1，KL-6，PEMT，EMA，Breast carcinoma-associated antigen DF3，Mucin 1， Transmembrane
시판 약물 수	0
임상 약물 수	28
최고 연구 개발 단계	Phase 2 Clinical

Mucin-1 제품 목록

속성
Protein (19)Antibody (1)Kits (1)
제품 라이브러리
온라인 (21)
종
Human (13)Cynomolgus (5)Mouse (3)
태그
Fc Tag (7)Llama IgG Fc Tag (1)His Tag (6)His Tag & Avi Tag (3)Mouse IgG Fc Tag (2)- (2)
마커
Unconjugated (16)Biotin-labeled (3)APC Labeled (1)- (1)

제품 번호	종	발현 시스템	제품 설명
HOT MU1-H52H5	Human	HEK293	Human Mucin-1 / MUC-1 (1036-1155) Protein, His Tag
HOT MU1-H52H9	Human	HEK293	Human Mucin-1 / MUC-1 (890-1158) Protein, His Tag, low endotoxin (MALS verified)
HOT MU1-H82E5	Human	HEK293	Biotinylated Human Mucin-1 (890-1158) Protein, His,Avitag™ (MALS verified)
CEA-B055	Human	-	Human MUCIN 1/MUC1 ELISA Kit
MU1-H5153	Human	E. coli	Human Mucin-1 / MUC-1 (116-173) Protein, Fc Tag
MU1-H5252	Human	HEK293	Human Mucin-1 / MUC-1 Protein, Fc Tag, low endotoxin
MU1-H5254	Human	HEK293	Human Mucin-1 / MUC-1 (24-380) Protein, Fc Tag
MU1-H5255	Human	HEK293	Human Mucin-1 / MUC-1 Protein, Llama IgG2b Fc Tag, low endotoxin
MU1-H5256	Human	HEK293	Human Mucin-1 / MUC-1 (116-173) Protein, Fc Tag
MU1-H5258	Human	HEK293	Human Mucin-1 / MUC-1 (890-1158) Protein, Fc Tag (MALS verified)

총 수량21

Mucin-1분자 배경

Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.

Mucin-1분자 별명

Mucin 1,MUC1,CD227,EMA,H23AG,KL-6,MAM6,MUC-1,SEC,MUC-1,X,MUC1,ZD,PEM,PEMT,PUM,CA15-3,Episialin

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Cancer vaccine (BN ImmunoTherapeutics/National Cancer Institute)	CVAC-301; CV-301	Phase 2 Clinical	Therion Biologics	Adenocarcinoma; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Colorectal Neoplasms; Cystadenocarcinoma; Intestinal Neoplasms; Melanoma; Neoplasm Metastasis; Ovarian Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Solid tumours; Urinary Bladder Neoplasms	상세
PD-1 Knockout Anti-MUC1 CAR-T Cells (Guangzhou Anjie Biomedical)	AJMUC1	Phase 2 Clinical	Guangzhou Anjie Biomedical Technology	Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Esophageal Neoplasms; Lung Neoplasms; Prostatic Neoplasms	상세
Anti-MUC1 monoclonal antibody (OncoQuest)	AR20.5; mAb-AR20.5; Anti-MUC1 AR20.5	Phase 2 Clinical	Altarex	Pancreatic Neoplasms	상세
GO-2032c	GO-203-2C	Phase 2 Clinical	Dana-Farber Cancer Institute, Genus Oncology Llc	Leukemia, Myeloid, Acute; Multiple Myeloma; Solid tumours	상세
MUC1-Poly-ICLC	MUC1-poly-ICLC	Phase 2 Clinical	University Of Pittsburgh	Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Melanoma	상세
EB-DT-CAR-NK	EB-DT-CAR-NK	Phase 2 Clinical	Beijing Biotech	Breast Neoplasms; Triple Negative Breast Neoplasms	상세
EB-DNK102	EB-DNK102	Phase 2 Clinical	Beijing Biotech	Carcinoma, Pancreatic Ductal	상세
EB-DNK101	EB-DNK101	Phase 2 Clinical	Beijing Biotech	Carcinoma, Pancreatic Ductal	상세
DS-3939	DS-3939; DS-3939a; GT-00A	Phase 2 Clinical	Daiichi Sankyo Inc	Solid tumours	상세
BM7PE		Phase 2 Clinical	Oslo University Hospital	Colorectal Neoplasms	상세
Anti-MUC1 CAR T-cell therapy (Guangzhou Anjie Biomedical Technology/University of Technology Sydney)		Phase 2 Clinical	Guangzhou Anjie Biomedical Technology, The First Affiliated Hospital Of Guangdong Pharmaceutical University, University of Sydney	Carcinoma, Non-Small-Cell Lung	상세
huMNC2-CAR44	huMNC2-CAR44	Phase 1 Clinical	Minerva Biotechnologies Co	Metastatic breast cancer	상세
ICTCAR-052	ICTCAR-052	Phase 1 Clinical	Innovative Cellular Therapeutics Co Ltd	Breast Neoplasms; Lung Neoplasms; Pancreatic Neoplasms	상세
recombinant adenovirus vector vaccine targeting MUC1 (MicroVax)		Phase 1 Clinical	Microvax Llc	Neoplasms	상세
P-MUC1C-ALLO1	P-MUC1C-ALLO1; P-MUC1C-101	Phase 1 Clinical	Poseida Therapeutics Inc	Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Colorectal Neoplasms; Nasopharyngeal Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms	상세
NEOK-002	ABL209; ABL-209; NEOK002; NEOK-002	Phase 1 Clinical	Abl Bio Inc, Biocytogen Pharmaceuticals (Beijing) Co Ltd	Neoplasms; Solid tumours	상세
M-0324	M-0324; M0324	Phase 1 Clinical	Merck KGaA, Darmstadt, Germany	Neoplasms; Solid tumours	상세
YB-01(Yuanben (Zhuhai Hengqin) Biotech)	YB01; YB-01	Phase 1 Clinical	Yuanben (Zhuhai Hengqin) Biotechnology Co Ltd	Arthritis, Rheumatoid; Solid tumours	상세
SBO-154	SBO-154	Phase 1 Clinical	Sun Pharmaceutical Advanced Research Co Ltd	Breast Neoplasms; Head and Neck Neoplasms; Pancreatic Neoplasms; Solid tumours	상세
ICTCAR-053	ICTCAR-053	Phase 1 Clinical	Innovative Cellular Therapeutics Co Ltd	Pancreatic Neoplasms	상세
BGB-B3227	BGB-B3227	Phase 1 Clinical	BeOne Medicines (Beijing) Co Ltd	Gastrointestinal Neoplasms; Lung Neoplasms; Neoplasm Metastasis; Neoplasms; Solid tumours	상세
MUC1-peptide-DC-CTL (Beijing Doing Biomedical)		Phase 1 Clinical	Beijing Doing Biomedical Co Ltd	Stomach Neoplasms	상세
MUC1-gene-DC-CTL (Beijing Doing Biomedical)		Phase 1 Clinical	Beijing Doing Biomedical Co Ltd	Stomach Neoplasms	상세
DM-002	DM-002; DM002 (Danma)	Phase 1 Clinical	Danma (Suzhou) Biomedical Technology Co Ltd	Colorectal Neoplasms; Endometrial Neoplasms; Ovarian Neoplasms; Prostatic Neoplasms; Solid tumours	상세
Recombinant HSP-MUC1 fusion protein (Newsummit)		Phase 1 Clinical	Shanghai Xinshengyuan Biological Medicine Co Ltd	Breast Neoplasms	상세
DXC-005	DXC-005	Phase 1 Clinical	Hangzhou Dac Biotech Company Ltd	Colorectal Neoplasms; Pancreatic Neoplasms; Solid tumours	상세
M-1231	M-1231	Phase 1 Clinical	Emd Serono Research & Development Institute Inc, Merck Serono	Carcinoma, Non-Small-Cell Lung; Esophageal Neoplasms; Solid tumours	상세
ICTCAR-046	ICTCAR-046	Clinical	Innovative Cellular Therapeutics Co Ltd	Pancreatic Neoplasms	상세