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Mucin-1

Mucin-1

Mucin-1 분자 정보

Molecule Name
Mucin-1
분자 별명
Mucin 1,MUC1,CD227,EMA,H23AG,KL-6,MAM6,MUC-1,SEC,MUC-1,X,MUC1,ZD,PEM,PEMT,PUM,CA15-3,Episialin
Drug Development Progress
임상 약물 수28
시판 약물 수0
최고 연구 개발 단계Phase 2 Clinical
표적 별명
PEM，Medullary Cystic Kidney Disease 1 (Autosomal Dominant)，Tumor Associated Epithelial Mucin，CD227 Antigen，H23 Antigen，MUC-1/SEC，ADMCKD1，Cancer antigen 15-3，Tumor-associated mucin，MUC1-alpha，MUC1-beta，MUC-1/X，MUC1/ZD，Mucin-1，ADMCKD，MCKD1，MAM6，MCKD，MCD，Polymorphic epithelial mucin，PUM，MUC1-NT，Episialin，CD227，MUC1-CT，MUC1，Mucin 1， Cell Surface Associated，Tumor-Associated Epithelial Membrane Antigen，Peanut-Reactive Urinary Mucin，Carcinoma-Associated Mucin，Krebs Von Den Lungen-6，CA 15-3，H23AG，MUC-1，KL-6，PEMT，EMA，Breast carcinoma-associated antigen DF3，Mucin 1， Transmembrane
분자 배경
Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.

Mucin-1 제품 목록

Species
  • Human（12）
  • Cynomolgus（5）
  • Mouse（2）
Tag
  • Fc Tag（7）
  • His Tag（6）
  • His Tag & Avi Tag（3）
  • Mouse IgG Fc Tag（2）
  • Llama IgG Fc Tag（1）
Host
  • HEK293（18）
  • E. coli（1）
Conjugate
  • Unconjugated（15）
  • Biotin-labeled（3）
  • APC Labeled（1）
Grade
  • RUO（19）
Low Endotoxin
  • Yes（5）
  • No（14）
분자Cat. No.Product Name종Host구조순도Activity규격 및 가격
Mucin-1
HOTAvitag
MU1-H82E5
Biotinylated Human Mucin-1 (890-1158) Protein, His,Avitag™ (MALS verified)
Human
HEK293
MALSSDS-PAGE
Flow

$380.00

25ug
Mucin-1
HOT
MU1-H52H5
Human Mucin-1 / MUC-1 (1036-1155) Protein, His Tag (Mass Spec verified)
Human
HEK293
SDS-PAGE
ELISAFlow

$360.00

100ug
Mucin-1
HOT
MU1-H52H9
Human Mucin-1 / MUC-1 (890-1158) Protein, His Tag, low endotoxin (MALS verified)
Human
HEK293
MALSSDS-PAGE
ELISA

$310.00

100ug
Mucin-1
MU1-C5252
Cynomolgus Mucin-1 / MUC-1 Protein, Fc Tag
Cynomolgus
HEK293
SDS-PAGE

$360.00

100ug
Mucin-1
MU1-C5253
Cynomolgus Mucin-1 / MUC-1 (128-376) Protein, Fc Tag (MALS verified)
Cynomolgus
HEK293
MALSSDS-PAGE
ELISA

$360.00

100ug
Mucin-1
MU1-C5254
Cynomolgus Mucin-1 / MUC-1 Protein, Mouse IgG2a Fc Tag, low endotoxin (MALS verified)
Cynomolgus
HEK293
MALSSDS-PAGE

$360.00

100ug
Mucin-1
MU1-C52H5
Cynomolgus Mucin-1 / MUC-1 Protein, His Tag
Cynomolgus
HEK293
SDS-PAGE

$360.00

100ug
Mucin-1
Avitag
MU1-C82E3
Biotinylated Cynomolgus Mucin-1 / MUC-1 Protein, His,Avitag™ (MALS verified)
Cynomolgus
HEK293
MALSSDS-PAGE
ELISA

$380.00

25ug
Mucin-1
MU1-H5153
Human Mucin-1 / MUC-1 (116-173) Protein, Fc Tag
Human
E. coli
SDS-PAGE

$360.00

100ug
Mucin-1
MU1-H5252
Human Mucin-1 / MUC-1 Protein, Fc Tag, low endotoxin
Human
HEK293
SDS-PAGE

$260.00

100ug
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임상 약물 정보

영어 이름연구 코드연구 개발 단계회사적응증임상 시험
Cancer vaccine (BN ImmunoTherapeutics/National Cancer Institute)CVAC-301; CV-301Phase 2 ClinicalTherion Biologics
Adenocarcinoma; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Colorectal Neoplasms; Cystadenocarcinoma; Intestinal Neoplasms; Melanoma; Neoplasm Metastasis; Ovarian Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Solid tumours; Urinary Bladder Neoplasms
상세
PD-1 Knockout Anti-MUC1 CAR-T Cells (Guangzhou Anjie Biomedical)AJMUC1Phase 2 ClinicalGuangzhou Anjie Biomedical Technology
Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Esophageal Neoplasms; Lung Neoplasms; Prostatic Neoplasms
상세
Anti-MUC1 monoclonal antibody (OncoQuest)AR20.5; mAb-AR20.5; Anti-MUC1 AR20.5Phase 2 ClinicalAltarex
Pancreatic Neoplasms
상세
GO-2032cGO-203-2CPhase 2 ClinicalDana-Farber Cancer Institute, Genus Oncology Llc
Leukemia, Myeloid, Acute; Multiple Myeloma; Solid tumours
상세
MUC1-Poly-ICLCMUC1-poly-ICLCPhase 2 ClinicalUniversity Of Pittsburgh
Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Melanoma
상세
EB-DT-CAR-NKEB-DT-CAR-NKPhase 2 ClinicalBeijing Biotech
Breast Neoplasms; Triple Negative Breast Neoplasms
상세
EB-DNK102EB-DNK102Phase 2 ClinicalBeijing Biotech
Carcinoma, Pancreatic Ductal
상세
EB-DNK101EB-DNK101Phase 2 ClinicalBeijing Biotech
Carcinoma, Pancreatic Ductal
상세
DS-3939DS-3939; DS-3939a; GT-00APhase 2 ClinicalDaiichi Sankyo Inc
Solid tumours
상세
BM7PEPhase 2 ClinicalOslo University Hospital
Colorectal Neoplasms
상세
Anti-MUC1 CAR T-cell therapy (Guangzhou Anjie Biomedical Technology/University of Technology Sydney)Phase 2 ClinicalGuangzhou Anjie Biomedical Technology, The First Affiliated Hospital Of Guangdong Pharmaceutical University, University of Sydney
Carcinoma, Non-Small-Cell Lung
상세
huMNC2-CAR44huMNC2-CAR44Phase 1 ClinicalMinerva Biotechnologies Co
Metastatic breast cancer
상세
ICTCAR-052ICTCAR-052Phase 1 ClinicalInnovative Cellular Therapeutics Co Ltd
Breast Neoplasms; Lung Neoplasms; Pancreatic Neoplasms
상세
recombinant adenovirus vector vaccine targeting MUC1 (MicroVax)Phase 1 ClinicalMicrovax Llc
Neoplasms
상세
P-MUC1C-ALLO1P-MUC1C-ALLO1; P-MUC1C-101Phase 1 ClinicalPoseida Therapeutics Inc
Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Colorectal Neoplasms; Nasopharyngeal Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms
상세
NEOK-002ABL209; ABL-209; NEOK002; NEOK-002Phase 1 ClinicalAbl Bio Inc, Biocytogen Pharmaceuticals (Beijing) Co Ltd
Neoplasms; Solid tumours
상세
M-0324M-0324; M0324Phase 1 ClinicalMerck KGaA, Darmstadt, Germany
Neoplasms; Solid tumours
상세
YB-01(Yuanben (Zhuhai Hengqin) Biotech)YB01; YB-01Phase 1 ClinicalYuanben (Zhuhai Hengqin) Biotechnology Co Ltd
Arthritis, Rheumatoid; Solid tumours
상세
SBO-154SBO-154Phase 1 ClinicalSun Pharmaceutical Advanced Research Co Ltd
Breast Neoplasms; Head and Neck Neoplasms; Pancreatic Neoplasms; Solid tumours
상세
ICTCAR-053ICTCAR-053Phase 1 ClinicalInnovative Cellular Therapeutics Co Ltd
Pancreatic Neoplasms
상세
BGB-B3227BGB-B3227Phase 1 ClinicalBeOne Medicines (Beijing) Co Ltd
Gastrointestinal Neoplasms; Lung Neoplasms; Neoplasm Metastasis; Neoplasms; Solid tumours
상세
MUC1-peptide-DC-CTL (Beijing Doing Biomedical)Phase 1 ClinicalBeijing Doing Biomedical Co Ltd
Stomach Neoplasms
상세
MUC1-gene-DC-CTL (Beijing Doing Biomedical)Phase 1 ClinicalBeijing Doing Biomedical Co Ltd
Stomach Neoplasms
상세
DM-002DM-002; DM002 (Danma)Phase 1 ClinicalDanma (Suzhou) Biomedical Technology Co Ltd
Colorectal Neoplasms; Endometrial Neoplasms; Ovarian Neoplasms; Prostatic Neoplasms; Solid tumours
상세
Recombinant HSP-MUC1 fusion protein (Newsummit)Phase 1 ClinicalShanghai Xinshengyuan Biological Medicine Co Ltd
Breast Neoplasms
상세
DXC-005DXC-005Phase 1 ClinicalHangzhou Dac Biotech Company Ltd
Colorectal Neoplasms; Pancreatic Neoplasms; Solid tumours
상세
M-1231M-1231Phase 1 ClinicalEmd Serono Research & Development Institute Inc, Merck Serono
Carcinoma, Non-Small-Cell Lung; Esophageal Neoplasms; Solid tumours
상세
ICTCAR-046ICTCAR-046ClinicalInnovative Cellular Therapeutics Co Ltd
Pancreatic Neoplasms
상세
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