Monoamine oxidase B

Monoamine oxidase B

Monoamine oxidase B 분자 정보

Molecule Name
Monoamine oxidase B
분자 별명
MAOB, MAO-B,Monoamine Oxidase B,Monoamine oxidase type B
Drug Development Progress
임상 약물 수13
시판 약물 수3
최고 연구 개발 단계Approved
표적 별명
EC:1.4.3.4,EC 1.4.3,MAOB,Amine oxidase [flavin-containing] B,Monoamine Oxidase B,Monoamine Oxidase Type B,MAO-B,Adrenalin Oxidase,Tyramine Oxidase,MAO, Platelet,MAO, Brain,EC 1.4.3.4
분자 배경
Monoamine Oxidase Type B (MAOB) is an enzyme located in the outer mitochondrial membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the breakdown of dopamine in the brain. MAOB inhibitors, that reduces dopamine turnover, are in clinical use for the treatment of Parkinson's disease (PD).

Monoamine oxidase B 제품 목록

Species
  • Human(1)
Tag
  • His Tag(1)
Host
  • InsectCells(1)
Conjugate
  • Unconjugated(1)
Grade
  • RUO(1)
Low Endotoxin
  • No(1)
분자Cat. No.Product Name종Host구조순도Activity규격 및 가격
Monoamine oxidase B
Human MAOB / Monoamine Oxidase B Protein, His Tag (active enzyme)
Human
InsectCells
SDS-PAGE
Enzyme

$245.00

20ug
You Have Viewed 1-1 Of 1 Results
  • 1

Can’t find what you need?

Submit your requirements and our technical
team will help.

Asset Licensing Opportunity

라이선싱 협력

프로젝트 이름약물 유형치료 영역적응증단계권리 지역
Reversible MAOB InhibitorSmall moleculeNeurological diseaseParkinson's diseasePhase IGlobal
프로젝트 이름
Reversible MAOB Inhibitor
약물 유형
Small molecule
치료 영역
Neurological disease
적응증
Parkinson's disease
단계
Phase I
권리 지역
Global
Resources

임상 약물 정보

영어 이름연구 코드연구 개발 단계회사적응증임상 시험
Pramipexole Dihydrochloride Hydrate/Rasagiline MesylateP2B-001Phase 3 ClinicalPharma Two B Ltd
Parkinson Disease
상세
VafidemstatORY-2001Phase 2 ClinicalOryzon Genomics Sa
Alzheimer Disease; Borderline Personality Disorder; Kabuki syndrome; Schizophrenia
상세
J-147J-147Phase 2 ClinicalSalk Institute
Alzheimer Disease; Ischemic Stroke
상세
TisolagilineKDS2010; KDS-2010Phase 2 ClinicalNeuroBiogen
Alzheimer Disease; Cognitive Dysfunction; Dementia; Obesity; Overweight
상세
Rasagiline transdermal patch (Teikoku Pharma)Phase 1 ClinicalTeikoku Pharma
Parkinson Disease
상세
SKL-PDYKP-10461; SKL-PDPhase 1 ClinicalSK Biopharmaceuticals Co Ltd
Parkinson Disease
상세
18F-FCOB0418F-FCOB04; 18F-FCOB-04Phase 1 ClinicalPeking Union Medical College Hospital
Neurodegenerative Diseases
상세
LNTH-2511Phase 1 ClinicalLantheus Holdings Inc
Neuroinflammatory Diseases
상세
Pramipexole and Rasagiline Mesylate Sustained-release Capsules(Zhejiang Jingxin Pharma)Phase 1 ClinicalZhejiang Jingxin Pharmaceutical Co Ltd
Parkinson Disease
상세
Rasagiline Mesylate Sublingual membrane(Shanghai Shangyao Zhongxi Pharma)Phase 1 ClinicalShanghai Shangyao Zhongxi Pharmaceutical Co Ltd
Parkinson Disease
상세
Rasagiline Mesylate Transdermal Patch(world leader)Phase 1 ClinicalGuizhou Shiling Pharmaceutical Co Ltd, Shanghai World Ling Pharmaceutical Co Ltd
Parkinson Disease
상세
HEC-122505MsOHHEC-122505MsOH; HEC-122505-MsOH; HEC122505MsOHPhase 1 ClinicalGuangdong Dongyangguang Pharmaceutical Co Ltd
Parkinson Disease
상세
18F-SMBT-118F-SMBT-1; 18-F-SMBT-1ClinicalTohoku University
상세

시판 약물 정보

영어 이름연구 코드연구 개발 단계회사가장 빠른 브랜드 이름가장 빠른 승인 국가가장 빠른 적응증가장 빠른 승인 회사가장 빠른 승인 날짜적응증임상 시험
Rasagiline MesylateLu 00-773; TVP-101; TV-1030; AGN-1135; TVP-1012ApprovedTevaAzilect, AgilectEUParkinson DiseaseTeva Bv2005-02-21
Alzheimer Disease; Dementia; Multiple System Atrophy; Parkinson Disease; REM Sleep Behavior Disorder; Restless Legs Syndrome; Supranuclear Palsy, Progressive; Synucleinopathies
상세
Selegiline HydrochlorideFPF-1100; E-250 (free base)ApprovedSanofiFP, Jumex, Otrasel, Seledat, Xilopar, Zelapar, Deprenyl, Eldepryl, Plurimen, Vivapryl, Zydis selegilineMainland ChinaParkinson DiseaseChinoin Pharmaceutical And Chemical Works Co Ltd1989-06-05
Amphetamine-Related Disorders; Borderline Personality Disorder; Cocaine-Related Disorders; Cognition Disorders; Depressive Disorder, Major; HIV Infections; Marijuana Abuse; Parkinson Disease; Schizophrenia; Tobacco Use Cessation; Tobacco Use Disorder
상세
Safinamide MesylatePNU-151774E; FCE-28073 (R-isomer); EMD-1195686; ZP-034; NW-1015; ME-2125; PNU-151774; FCE-26743ApprovedNewron PharmaceuticalXadago, EqufinaEUParkinson DiseaseZambon Spa2015-02-23
Dyskinesia, Drug-Induced; Hepatic Insufficiency; Multiple System Atrophy; Parkinson Disease; Renal Insufficiency
상세
Customer Reviews