언어 선택

MMP-3

MMP-3 분자 정보

영어 이름	Matrix metalloproteinase 3	시판 약물 수	0
임상 약물 수	0	표적 별명	CHDS6，STR1，STMY，Matrix Metalloproteinase 3，Matrix metalloproteinase-3，MMP-3，SL-1，STMY1，MMP3，Matrix Metalloproteinase 3 (Stromelysin 1， Progelatinase)，Transin-1，Proteoglycanase，Stromelysin-1，Stromelysin 1，EC 3.4.24.17，EC:3.4.24.17，EC 3.4.24，Matrix Metallopeptidase 3
최고 연구 개발 단계	Preclinical

영어 이름	Matrix metalloproteinase 3
표적 별명	CHDS6，STR1，STMY，Matrix Metalloproteinase 3，Matrix metalloproteinase-3，MMP-3，SL-1，STMY1，MMP3，Matrix Metalloproteinase 3 (Stromelysin 1， Progelatinase)，Transin-1，Proteoglycanase，Stromelysin-1，Stromelysin 1，EC 3.4.24.17，EC:3.4.24.17，EC 3.4.24，Matrix Metallopeptidase 3
시판 약물 수	0
임상 약물 수	0
최고 연구 개발 단계	Preclinical

MMP-3 제품 목록

속성
Protein (1)
제품 라이브러리
온라인 (1)
종
Human (1)
태그
His Tag (1)
마커
Unconjugated (1)

제품 번호	종	발현 시스템	제품 설명	단백질 구조	순도	특성
MM3-H52H3	Human	HEK293	Human MMP-3 Protein, His Tag (Pro-form, MALS verified)

총 수량1

MMP-3분자 배경

Matrix metalloproteinase 3 (MMP-3), also known as stromelysin 1 and progelatinase, is encoded by the MMP3 gene. The expression of MMP3 is mainly regulated at the transcriptional level, where gene promoters respond to a variety of stimuli including growth factors, cytokines, carcinogens and proto-oncogene products. MMP-3 degrade II, III, IV, IX and X collagen, proteoglycan, fibronectin, laminin, and elastin. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7 and MMP-9, so MMP-3 plays a key role in connective tissue remodeling. This enzyme is involved in wound repair, atherosclerotic progression, and tumor initiation. Studies of MMP-3 wild type and gene knockout in mice have shown that MMP-3 increases the permeability of the blood-brain barrier after traumatic injury. Nuclear MMP-3 works as a transcription factor and protease.