MIS RII

MIS RII 분자 정보

영어 이름Anti-Mullerian hormone receptor II시판 약물 수0
임상 약물 수0표적 별명Anti-Mullerian Hormone Receptor, Type II,AMHR2,MRII,AMH Type II Receptor,MISRII,Muellerian Inhibiting Substance Type II Receptor,MIS Type II Receptor,Anti-Muellerian hormone type-2 receptor,EC:2.7.11.30,Mullerian Inhibiting Substance Type II Receptor,MISR2,AMHR,Anti-Muellerian Hormone Type-2 Receptor,Anti-Mullerian Hormone Receptor Type 2,EC 2.7.11.30,Anti-Muellerian Hormone Type II Receptor,Anti-Mullerian Hormone Receptor Type II
최고 연구 개발 단계Preclinical
영어 이름Anti-Mullerian hormone receptor II
표적 별명Anti-Mullerian Hormone Receptor, Type II,AMHR2,MRII,AMH Type II Receptor,MISRII,Muellerian Inhibiting Substance Type II Receptor,MIS Type II Receptor,Anti-Muellerian hormone type-2 receptor,EC:2.7.11.30,Mullerian Inhibiting Substance Type II Receptor,MISR2,AMHR,Anti-Muellerian Hormone Type-2 Receptor,Anti-Mullerian Hormone Receptor Type 2,EC 2.7.11.30,Anti-Muellerian Hormone Type II Receptor,Anti-Mullerian Hormone Receptor Type II
시판 약물 수0
임상 약물 수0
최고 연구 개발 단계Preclinical

MIS RII 제품 목록

  • 속성

    Protein (7)

  • 제품 라이브러리

    온라인 (7)

  • Human (5)Cynomolgus (1)Mouse (1)

  • 태그

    Fc Tag (1)His Tag (3)His Tag & Avi Tag (1)Mouse IgG Fc Tag (1)Llama IgG Fc Tag (1)

  • 마커

    Unconjugated (6)Biotin-labeled (1)

MIS RII분자 배경

MIS RII (Mullerian inhibiting substance type II receptor), also known as AMHRII (anti-Mullerian hormone type II receptor), is a serine/threonine receptor with a single transmembrane domain that belongs to the family of type II receptors of the TGF-beta superfamily. Mutations in MIS RII result in persistent Mullerian duct syndrome (PMDS), persistent Müllerian duct syndrome (PMDS) is a sex-limited disorder in which males develop portions of the female reproductive tract. Anti-Müllerian hormone (AMH) and its receptor (AMHR2) induce the regression of the Müllerian ducts in male embryos, but the mechanism by which the Amhr2 gene is specifically activated is not fully understood.

MIS RII분자 별명

MIS RII,MRII,AMHR2,AMHR,MISR2,AMH type II receptor

제품 리뷰

  • K***n2025-04-29
    0사람들이 좋아합니다
    We purchased this protein and validated its binding to its natural ligand, MIS. We saw great binding between the hMISRII-hFc and MIS ligand, which was exactly what we expected. Additionally, this protein passed our QC requirements for purity on SDS-PAGE and SEC. This was purchased along with several other MISRII products from other companies and this was the only material that bound MIS with expected affinity. As such, we plan to use this protein for our downstream applications.
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