언어 선택

MIF

MIF 분자 정보

영어 이름	Macrophage migration inhibitory factor	시판 약물 수	1
임상 약물 수	3	표적 별명	EC:5.3.2.1，GIF，EC 5.3.3.12，EC 5.3.2.1，Macrophage Migration-Inhibitory Factors，Epididymis Secretory Sperm Binding Protein，EC:5.3.3.12，Phenylpyruvate Tautomerase，L-Dopachrome Tautomerase，MMIF，Glycosylation-inhibiting factor，L-dopachrome isomerase，MIF，Macrophage Migration Inhibitory Factor，Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor)，GLIF
최고 연구 개발 단계	Approved

영어 이름	Macrophage migration inhibitory factor
표적 별명	EC:5.3.2.1，GIF，EC 5.3.3.12，EC 5.3.2.1，Macrophage Migration-Inhibitory Factors，Epididymis Secretory Sperm Binding Protein，EC:5.3.3.12，Phenylpyruvate Tautomerase，L-Dopachrome Tautomerase，MMIF，Glycosylation-inhibiting factor，L-dopachrome isomerase，MIF，Macrophage Migration Inhibitory Factor，Macrophage Migration Inhibitory Factor (Glycosylation-Inhibiting Factor)，GLIF
시판 약물 수	1
임상 약물 수	3
최고 연구 개발 단계	Approved

MIF 제품 목록

속성
Protein (1)
제품 라이브러리
온라인 (1)
종
Human (1)
태그
His Tag & Avi Tag (1)
마커
Biotin-labeled (1)

제품 번호	종	발현 시스템	제품 설명	단백질 구조	순도	특성
MIF-H82E7	Human	HEK293	Biotinylated Human MIF Protein, His,Avitag™

총 수량1

MIF분자 배경

Macrophage migration inhibitory factor(MIF) is also known as Glycosylation-inhibiting factor(GIF), L-dopachrome isomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase. Interacts with CXCR2 extracellular domain, CD74 extracellular domain, COPS5 and BNIPL. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.

MIF분자 별명

MIF,GLIF,MMIF,GIF

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
IPG-1094	IPG-1094; IPG-001	Phase 2 Clinical	Nanjing Immunophage Biotech Co Ltd	Brain metastases; Brain Neoplasms; Hematologic Neoplasms; Lupus Nephritis; Multiple Myeloma; Multiple Sclerosis; Psoriasis; Solid tumours	상세
TRP2-electroporated autologous dendritic cell therapy (Memorial Sloan-Kettering)		Phase 1 Clinical	Memorial Sloan Kettering Cancer Center	Melanoma	상세
STP-1	STP-1; STP1	Phase 1 Clinical	Stalicla Sa	Autism Spectrum Disorder	상세

시판 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	가장 빠른 브랜드 이름	가장 빠른 승인 국가	가장 빠른 적응증	가장 빠른 승인 회사	가장 빠른 승인 날짜	적응증	임상 시험
Ibudilast	KC-404; AV-411; MN-166	Approved	Kyorin Pharmaceutical Co Ltd	Ketas, Pinatos, Eyevinal	Japan	Asthma; Multiple Sclerosis; Neuralgia	Kyorin Pharmaceutical Co Ltd		Alcoholism; Amyotrophic Lateral Sclerosis; Asthma; Diabetic Neuropathies; Headache Disorders, Secondary; HIV Infections; Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Neuralgia; Opioid-Related Disorders; Pneumonia, Viral; Substance-Related Disorders	상세

제품 리뷰

S***n2023-04-28
0사람들이 좋아합니다
Biotinylated Human MIF Protein, His,Avitag™
This product was used for characterization of a novel therapeutic testing kinetics and affinity on SPR with a Cytiva BiotinCAPture kit. It worked phenomenally with both the novel approach and a positive control. Additionally, it was used with a Streptavidin coated ELISA plate (also from Acro), results were phenomenal with that approach as well. Overall, this product has been well received by our team and we have already ordered more to continue testing.