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LTBR

LTBR 분자 정보

영어 이름	Tumor necrosis factor receptor superfamily member 3	시판 약물 수	0
임상 약물 수	1	표적 별명	Lymphotoxin-beta receptor，Tumor necrosis factor receptor type III，LTBR，Tumor necrosis factor receptor superfamily member 3，D12S370，TNFRSF3，TNFCR，TNFR3，TNFR Superfamily， Member 3，Lymphotoxin B Receptor，LT-BETA-R，TNF-R-III，TNFR2-RP，TNF-RIII，TNFR-III，TNFR-RP，Lymphotoxin beta Receptor，Tumor necrosis factor C receptor，Tumor Necrosis Factor Receptor 2-Related Protein，Lymphotoxin Beta Receptor (TNFR Superfamily， Member 3)
최고 연구 개발 단계	Phase 1 Clinical

영어 이름	Tumor necrosis factor receptor superfamily member 3
표적 별명	Lymphotoxin-beta receptor，Tumor necrosis factor receptor type III，LTBR，Tumor necrosis factor receptor superfamily member 3，D12S370，TNFRSF3，TNFCR，TNFR3，TNFR Superfamily， Member 3，Lymphotoxin B Receptor，LT-BETA-R，TNF-R-III，TNFR2-RP，TNF-RIII，TNFR-III，TNFR-RP，Lymphotoxin beta Receptor，Tumor necrosis factor C receptor，Tumor Necrosis Factor Receptor 2-Related Protein，Lymphotoxin Beta Receptor (TNFR Superfamily， Member 3)
시판 약물 수	0
임상 약물 수	1
최고 연구 개발 단계	Phase 1 Clinical

LTBR 제품 목록

속성
Protein (5)
제품 라이브러리
온라인 (5)
종
Human (3)Cynomolgus (1)Mouse (1)
태그
His Tag & Avi Tag (2)Fc Tag (1)His Tag (2)
마커
Biotin-labeled (1)Unconjugated (4)

제품 번호	종	발현 시스템	제품 설명
HOT LTR-H5259	Human	HEK293	Human LTBR / TNFRSF3 Protein, Fc Tag (MALS verified)
HOT LTR-H52E3	Human	HEK293	Unconjugated Human LTBR / TNFRSF3 Protein, His,Avitag™ (MALS verified)
HOT LTR-H82E9	Human	HEK293	Biotinylated Human LTBR / TNFRSF3 Protein, His,Avitag™ (MALS verified)
LTR-M52H3	Mouse	HEK293	Mouse LTBR / TNFRSF3 Protein, His Tag (MALS verified)
LTR-C52H3	Cynomolgus	HEK293	Cynomolgus LTBR / TNFRSF3 Protein, His Tag

총 수량5

LTBR분자 배경

Lymphotoxin-beta receptor (LTBR) is also known as Tumor necrosis factor receptor superfamily member 3 (TNFRSF3), Tumor necrosis factor receptor type III (TNF-RIII), which is a single-pass type I membrane protein containing four TNFR-Cys repeat regions. Except for interacting with HCV core protein, LTBR can not only associate with itself, but also can associate with TRAF3, TRAF4 and TRAF5. As the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT, LTBR promotes apoptosis via TRAF3 and TRAF5. Furthermore, LTBR may play a role in the development of lymphoid organs.