LRP-1

LRP-1 분자 정보

영어 이름Low density lipoprotein receptor-related protein-1시판 약물 수0
임상 약물 수0표적 별명Apolipoprotein E Receptor,TbetaR-V/LRP-1/IGFBP-3 Receptor,Type V Tgf-Beta Receptor,CD91 Antigen,APOER,Alpha-2-Macroglobulin Receptor,IGFBP3R1,IGFBP3R,TGFBR5,IGFBP-3R,LRP1A,CD91,A2MR,Prolow-Density Lipoprotein Receptor-Related Protein 1,Low Density Lipoprotein Receptor-Related Protein 1
최고 연구 개발 단계Preclinical
영어 이름Low density lipoprotein receptor-related protein-1
표적 별명Apolipoprotein E Receptor,TbetaR-V/LRP-1/IGFBP-3 Receptor,Type V Tgf-Beta Receptor,CD91 Antigen,APOER,Alpha-2-Macroglobulin Receptor,IGFBP3R1,IGFBP3R,TGFBR5,IGFBP-3R,LRP1A,CD91,A2MR,Prolow-Density Lipoprotein Receptor-Related Protein 1,Low Density Lipoprotein Receptor-Related Protein 1
시판 약물 수0
임상 약물 수0
최고 연구 개발 단계Preclinical

LRP-1분자 배경

Low density lipoprotein receptor-related protein 1 (LRP1), also known as alpha-2-macroglobulin receptor (A2MR), apolipoprotein E receptor (APOER) or cluster of differentiation 91 (CD91), is a protein forming a receptor found in the plasma membrane of cells. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor. LRP1 is also a key signalling protein and, thus, involved in various biological processes, such as lipoprotein metabolism and cell motility, and diseases, such as neurodegenerative diseases, atherosclerosis, and cancer.

LRP-1분자 별명

A2MR, APOER, APR, CD91, IGFBP-3R, IGFBP3R, IGFBP3R1, KPA, LRP, LRP1A, TGFBR5
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