언어 선택

LILRB2

LILRB2 분자 정보

영어 이름	Leukocyte immunoglobulin-like receptor subfamily B member 2	시판 약물 수	0
임상 약물 수	11	표적 별명	Leukocyte immunoglobulin-like receptor 2，CD85 antigen-like family member D，Immunoglobulin-like transcript 4，ILT-4，Monocyte/macrophage immunoglobulin-like receptor 10，MIR-10，CD_antigen: CD85d，LILRB2，Leukocyte Immunoglobulin Like Receptor B2，Leucocyte Ig-Like Receptor B2，MIR10，Leukocyte Immunoglobulin-Like Receptor， Subfamily B (With TM And ITIM Domains)， Member 2，Ig-Like Transcript 4，Myeloid Inhibitory Receptor 10，CD85d Antigen，ILT4，LIR2，CD85d，LIR-2，LIRB2
최고 연구 개발 단계	Phase 2 Clinical

영어 이름	Leukocyte immunoglobulin-like receptor subfamily B member 2
표적 별명	Leukocyte immunoglobulin-like receptor 2，CD85 antigen-like family member D，Immunoglobulin-like transcript 4，ILT-4，Monocyte/macrophage immunoglobulin-like receptor 10，MIR-10，CD_antigen: CD85d，LILRB2，Leukocyte Immunoglobulin Like Receptor B2，Leucocyte Ig-Like Receptor B2，MIR10，Leukocyte Immunoglobulin-Like Receptor， Subfamily B (With TM And ITIM Domains)， Member 2，Ig-Like Transcript 4，Myeloid Inhibitory Receptor 10，CD85d Antigen，ILT4，LIR2，CD85d，LIR-2，LIRB2
시판 약물 수	0
임상 약물 수	11
최고 연구 개발 단계	Phase 2 Clinical

LILRB2 제품 목록

속성
Protein (6)
제품 라이브러리
온라인 (6)
종
Human (4)Cynomolgus (2)
태그
His Tag (2)Fc Tag & Avi Tag (1)His Tag & Avi Tag (2)Fc Tag (1)
마커
Unconjugated (3)Biotin-labeled (3)

제품 번호	종	발현 시스템	제품 설명
HOT LI2-H5220	Human	HEK293	Human LILRB2 / CD85d / ILT4 Protein, His Tag, low endotoxin (MALS verified)
HOT LI2-H5253	Human	HEK293	Human LILRB2 / CD85d / ILT4 Protein, Fc Tag (MALS verified)
HOT LI2-H82E7	Human	HEK293	Biotinylated Human LILRB2 / CD85d / ILT4 Protein, His,Avitag™ (MALS verified)
HOT LI2-H82F5	Human	HEK293	Biotinylated Human LILRB2 / CD85d / ILT4 Protein, Fc,Avitag™ (MALS verified)
LI2-C52H3	Cynomolgus	HEK293	Cynomolgus LILRB2 / CD85d / ILT4 Protein, His Tag
LI2-C82E3	Cynomolgus	HEK293	Biotinylated Cynomolgus LILRB2 / CD85d / ILT4 Protein, His,Avitag™

총 수량6

LILRB2분자 배경

Leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2) is also known as CD85 antigen-like family member D (CD85d), Immunoglobulin-like transcript 4 (ILT-4), Monocyte / macrophage immunoglobulin-like receptor 10 (MIR-10), which is a member of the the subfamily B class of LIR receptors. LILRB2 is receptor for class I MHC antigens. LILRB2 recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB2 competes with CD8A for binding to class I MHC antigens. LILRB2 / CD85d inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

LILRB2분자 별명

LILRB2,ILT4,LIR2,MIR10,CD85d

항체 프로젝트 거래 플랫폼

프로젝트 이름	프로젝트 단계	분자 유형	분자 출처	질병 영역	적응증
LILRB2 mAb - 01	PCC	Monoclonal	Humanized Mouse	Solid Tumor	Solid tumor

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Polzastobart	JTX-8064	Phase 2 Clinical	Jounce Therapeutics Inc	Neoplasms	상세
IO-108	IO-108	Phase 2 Clinical	Yiming Biomedical Technology (Hangzhou) Co Ltd	Liver Neoplasms; Solid tumours	상세
MK-4830	MK-4830	Phase 2 Clinical	Agenus Inc	Carcinoma, Non-Small-Cell Lung; Carcinoma, Ovarian Epithelial; Cystadenocarcinoma, Serous; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Ovarian Neoplasms; Solid tumours	상세
SPX-303	SPX-303	Phase 2 Clinical	SparX Biopharmaceutical Corp	Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Colorectal Neoplasms; Gastroesophageal Junction Neoplasms; Melanoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms	상세
OR-502	OR502; OR-502	Phase 2 Clinical	OncoResponse Inc	Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis; Neoplasms; Skin Melanoma; Solid tumours	상세
NGM-707	NGM-707	Phase 2 Clinical	Merck & Co, NGM Biopharmaceuticals Inc	Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cholangiocarcinoma; Colorectal Neoplasms; Esophageal Neoplasms; Glioblastoma; Melanoma; Mesothelioma; Ovarian Neoplasms; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Uterine Cervical Neoplasms	상세
AK-150 (Akeso)	AK150; AK-150	Phase 1 Clinical		Solid tumours	상세
CHS-1000	CHS-1000	Phase 1 Clinical	Coherus Biosciences Inc	Solid tumours	상세
BMS-986406	BMS-986406; ONO-7226	Phase 1 Clinical	Bristol-Myers Squibb Company	Neoplasms	상세
CDX-585	CDX-585; BSI-585	Phase 1 Clinical	Biosion Inc, Celldex Therapeutics	Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Cholangiocarcinoma; Colorectal Neoplasms; Esophageal Neoplasms; Fallopian Tube Neoplasms; Head and Neck Neoplasms; Liver Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Solid tumours; Stomach Neoplasms	상세
ES-009	ES-009	Phase 1 Clinical	Elpiscience (Shanghai) Biopharma Ltd	Neoplasms; Solid tumours	상세