언어 선택

LILRB1

LILRB1 분자 정보

영어 이름	Leukocyte immunoglobulin-like receptor B1	시판 약물 수	0
임상 약물 수	6	표적 별명	Leukocyte Immunoglobulin Like Receptor B1，LIR-1，MIR-7，ILT2，LIR1，Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1 Soluble Isoform，PIR-B，Leukocyte immunoglobulin-like receptor 1，MIR7，PIRB，CD85j，Immunoglobulin-like transcript 2，Leukocyte Immunoglobulin-Like Receptor， Subfamily B (With TM And ITIM Domains)， Member 1，Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1，Monocyte/Macrophage Immunoglobulin-Like Receptor 7，CD85 Antigen-Like Family Member J，Myeloid Inhibitory Receptor 7，Leucocyte Ig-Like Receptor B1，ILT-2，CD85j Antigen，Ig-Like Transcript 2
최고 연구 개발 단계	Phase 2 Clinical

영어 이름	Leukocyte immunoglobulin-like receptor B1
표적 별명	Leukocyte Immunoglobulin Like Receptor B1，LIR-1，MIR-7，ILT2，LIR1，Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1 Soluble Isoform，PIR-B，Leukocyte immunoglobulin-like receptor 1，MIR7，PIRB，CD85j，Immunoglobulin-like transcript 2，Leukocyte Immunoglobulin-Like Receptor， Subfamily B (With TM And ITIM Domains)， Member 1，Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1，Monocyte/Macrophage Immunoglobulin-Like Receptor 7，CD85 Antigen-Like Family Member J，Myeloid Inhibitory Receptor 7，Leucocyte Ig-Like Receptor B1，ILT-2，CD85j Antigen，Ig-Like Transcript 2
시판 약물 수	0
임상 약물 수	6
최고 연구 개발 단계	Phase 2 Clinical

LILRB1 제품 목록

속성
Protein (7)
제품 라이브러리
온라인 (7)
종
Human (6)Cynomolgus (1)
태그
Fc Tag (1)Fc Tag & Avi Tag (2)His Tag (3)His Tag & Avi Tag (1)
마커
Unconjugated (4)Biotin-labeled (3)

제품 번호	종	발현 시스템	제품 설명
HOT AIDD‑Ready CDJ-H52H4	Human	HEK293	Human LILRB1 / CD85j / ILT2 Protein, His Tag (MALS verified)
HOT AIDD‑Ready CDJ-H52H6	Human	HEK293	Human LILRB1 / CD85j / ILT2 (23-431) Protein, His Tag (MALS verified)
HOT CDJ-H82E8	Human	HEK293	Biotinylated Human LILRB1 / CD85j / ILT2 Protein, His,Avitag™ (MALS verified)
HOT CDJ-C52H3	Cynomolgus	HEK293	Cynomolgus LILRB1 / CD85j / ILT2 Protein, His Tag
CDJ-H5252	Human	HEK293	Human LILRB1 / CD85j / ILT2 Protein, Fc Tag (MALS verified)
CDJ-H82F7	Human	HEK293	Biotinylated Human LILRB1 / CD85j / ILT2 Protein, Fc,Avitag™
CDJ-H82F9	Human	HEK293	Biotinylated Human LILRB1 / CD85j / ILT2 Protein, Fc,Avitag™ (MALS verified)

총 수량7

제품 문의

LILRB1분자 배경

CD85 antigen-like family member J (CD85J) is also known as Leukocyte immunoglobulin-like receptor subfamily B member 1 (LILRB1 or LIR-1), Immunoglobulin-like transcript 2 (ILT-2), Monocyte/macrophage immunoglobulin-like receptor 7 (MIR7), which belongs to leukocyte immunoglobulin-like receptor (LIR) family. CD85J / LILRB1 Contains 4 Ig-like C2-type (immunoglobulin-like) domains. CD85J / LIR-1 is expressed predominantly on B-cells and monocytes. CD85J is receptor for class I MHC antigens and recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles and is also receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. CD85J / LILRB1 interaction with HLA-B or HLA-E leads to inhibition of the signal triggered by FCER1A and inhibits serotonin release. CD85J / LILRB1 inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

LILRB1분자 별명

CD85J,LILRB1,CD85,ILT2,LIR1,MIR7

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
NGM-707	NGM-707	Phase 2 Clinical	Merck & Co, NGM Biopharmaceuticals Inc	Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cholangiocarcinoma; Colorectal Neoplasms; Esophageal Neoplasms; Glioblastoma; Melanoma; Mesothelioma; Ovarian Neoplasms; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Uterine Cervical Neoplasms	상세
Zamristobart	BND-22; SAR-444881	Phase 2 Clinical	Biond Biologics Ltd	Neoplasms; Solid tumours	상세
IOS-1002	ios-H2	Phase 1 Clinical	ImmunOs Therapeutics AG	Hematologic Neoplasms; Solid tumours	상세
AK-150 (Akeso)	AK150; AK-150	Phase 1 Clinical		Solid tumours	상세
LB-LR1109	LB-LR1109; LR-19155; LR19155	Phase 1 Clinical	Lg Chemical Ltd	Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Melanoma; Neoplasms; Solid tumours; Squamous Cell Carcinoma of Head and Neck	상세
AGEN-1571	AGEN-1571	Phase 1 Clinical	Agenus Inc	Neoplasms; Solid tumours	상세

제품 리뷰

M***n2025-04-24
0사람들이 좋아합니다
Biotinylated Human LILRB1 / CD85j / ILT2 Protein, Fc,Avitag™
This protein product from Acrobio Systems is high-quality and easy to use. The biotinylation via Avitag™ ensures consistent labeling, and the Fc tag provides good stability. It worked well in our binding assays, delivering reliable and reproducible results. Great option for researchers studying immune checkpoints or receptor-ligand interactions. Additionally, the protein was delivered quickly and arrived in excellent condition, with clear documentation and high purity confirmed by SDS-PAGE. It demonstrated strong and specific binding in flow cytometry and ELISA setups. The consistent performance across experiments made it a dependable tool in our studies. Highly recommended for immunology and cell biology applications where ligand-receptor interactions are key.
M***h2022-04-01
0사람들이 좋아합니다
Biotinylated Human LILRB1 / CD85j / ILT2 Protein, Fc,Avitag™
This sample was highly pure which was very helpful in selection campaigns to find specific molecules. We did our own QC on the sample to verify purity and it matched up perfectly with SDS-PAGE and SEC-MALS that is provided on the website. Shipping was quick to prevent delays in our project timelines. This sample was sent lyophilized and very easy to reconstitute for use.