언어 선택
LILRB1
LILRB1 분자 정보
| 영어 이름 | Leukocyte immunoglobulin-like receptor B1 | 시판 약물 수 | 0 |
| 임상 약물 수 | 6 | 표적 별명 | Leukocyte Immunoglobulin Like Receptor B1，LIR-1，MIR-7，ILT2，LIR1，Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1 Soluble Isoform，PIR-B，Leukocyte immunoglobulin-like receptor 1，MIR7，PIRB，CD85j，Immunoglobulin-like transcript 2，Leukocyte Immunoglobulin-Like Receptor， Subfamily B (With TM And ITIM Domains)， Member 1，Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1，Monocyte/Macrophage Immunoglobulin-Like Receptor 7，CD85 Antigen-Like Family Member J，Myeloid Inhibitory Receptor 7，Leucocyte Ig-Like Receptor B1，ILT-2，CD85j Antigen，Ig-Like Transcript 2 |
| 최고 연구 개발 단계 | Phase 2 Clinical | ||
| 영어 이름 | Leukocyte immunoglobulin-like receptor B1 |
| 표적 별명 | Leukocyte Immunoglobulin Like Receptor B1，LIR-1，MIR-7，ILT2，LIR1，Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1 Soluble Isoform，PIR-B，Leukocyte immunoglobulin-like receptor 1，MIR7，PIRB，CD85j，Immunoglobulin-like transcript 2，Leukocyte Immunoglobulin-Like Receptor， Subfamily B (With TM And ITIM Domains)， Member 1，Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 1，Monocyte/Macrophage Immunoglobulin-Like Receptor 7，CD85 Antigen-Like Family Member J，Myeloid Inhibitory Receptor 7，Leucocyte Ig-Like Receptor B1，ILT-2，CD85j Antigen，Ig-Like Transcript 2 |
| 시판 약물 수 | 0 |
| 임상 약물 수 | 6 |
| 최고 연구 개발 단계 | Phase 2 Clinical |
LILRB1 제품 목록
- 속성
Protein (7)
- 제품 라이브러리
온라인 (7)
- 종
Human (6)Cynomolgus (1)
- 태그
Fc Tag (1)Fc Tag & Avi Tag (2)His Tag (3)His Tag & Avi Tag (1)
- 마커
Unconjugated (4)Biotin-labeled (3)
총 수량7
- 1
LILRB1분자 배경
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
LILRB1분자 별명
CD85J,LILRB1,CD85,ILT2,LIR1,MIR7
임상 약물 정보
| 영어 이름 | 연구 코드 | 연구 개발 단계 | 회사 | 적응증 | 임상 시험 |
|---|---|---|---|---|---|
| NGM-707 | NGM-707 | Phase 2 Clinical | Merck & Co, NGM Biopharmaceuticals Inc | Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cholangiocarcinoma; Colorectal Neoplasms; Esophageal Neoplasms; Glioblastoma; Melanoma; Mesothelioma; Ovarian Neoplasms; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Uterine Cervical Neoplasms | 상세 |
| Zamristobart | BND-22; SAR-444881 | Phase 2 Clinical | Biond Biologics Ltd | Neoplasms; Solid tumours | 상세 |
| IOS-1002 | ios-H2 | Phase 1 Clinical | ImmunOs Therapeutics AG | Hematologic Neoplasms; Solid tumours | 상세 |
| AK-150 (Akeso) | AK150; AK-150 | Phase 1 Clinical | Solid tumours | 상세 | |
| LB-LR1109 | LB-LR1109; LR-19155; LR19155 | Phase 1 Clinical | Lg Chemical Ltd | Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Melanoma; Neoplasms; Solid tumours; Squamous Cell Carcinoma of Head and Neck | 상세 |
| AGEN-1571 | AGEN-1571 | Phase 1 Clinical | Agenus Inc | Neoplasms; Solid tumours | 상세 |
제품 리뷰
M***n2025-04-24
0사람들이 좋아합니다This protein product from Acrobio Systems is high-quality and easy to use. The biotinylation via Avitag™ ensures consistent labeling, and the Fc tag provides good stability. It worked well in our binding assays, delivering reliable and reproducible results. Great option for researchers studying immune checkpoints or receptor-ligand interactions. Additionally, the protein was delivered quickly and arrived in excellent condition, with clear documentation and high purity confirmed by SDS-PAGE. It demonstrated strong and specific binding in flow cytometry and ELISA setups. The consistent performance across experiments made it a dependable tool in our studies. Highly recommended for immunology and cell biology applications where ligand-receptor interactions are key.- M***h2022-04-01 0사람들이 좋아합니다This sample was highly pure which was very helpful in selection campaigns to find specific molecules. We did our own QC on the sample to verify purity and it matched up perfectly with SDS-PAGE and SEC-MALS that is provided on the website. Shipping was quick to prevent delays in our project timelines. This sample was sent lyophilized and very easy to reconstitute for use.
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