언어 선택

LIF

LIF 분자 정보

영어 이름	Leukemia inhibitory factor	시판 약물 수	0
임상 약물 수	2	표적 별명	LIF Interleukin 6 Family Cytokine，D factor，Emfilermin，LIF，Differentiation-stimulating factor，LIF， Interleukin 6 Family Cytokine，Differentiation Inhibitory Activity，Cholinergic Differentiation Factor，Hepatocyte-Stimulating Factor III，Differentiation-Inducing Factor，Melanoma-Derived LPL Inhibitor，Human Interleukin In DA Cells，Leukemia Inhibitory Factor，HILDA，MLPLI，CDF，DIA
최고 연구 개발 단계	Phase 2 Clinical

영어 이름	Leukemia inhibitory factor
표적 별명	LIF Interleukin 6 Family Cytokine，D factor，Emfilermin，LIF，Differentiation-stimulating factor，LIF， Interleukin 6 Family Cytokine，Differentiation Inhibitory Activity，Cholinergic Differentiation Factor，Hepatocyte-Stimulating Factor III，Differentiation-Inducing Factor，Melanoma-Derived LPL Inhibitor，Human Interleukin In DA Cells，Leukemia Inhibitory Factor，HILDA，MLPLI，CDF，DIA
시판 약물 수	0
임상 약물 수	2
최고 연구 개발 단계	Phase 2 Clinical

LIF 제품 목록

속성
Protein (6)
제품 라이브러리
온라인 (6)
종
Human (4)Mouse (2)
태그
Tag Free (3)His Tag (2)His Tag & Avi Tag (1)
마커
Unconjugated (5)Biotin-labeled (1)

제품 번호	종	발현 시스템	제품 설명
HOT LIF-H521b	Human	HEK293	Human LIF Protein, Tag Free
HOT LIF-H52H3	Human	HEK293	Human LIF Protein, His Tag (MALS verified)
HOT LIF-H82E2	Human	HEK293	Biotinylated Human LIF Protein, His,Avitag™
LIF-H5215	Human	HEK293	Human LIF Protein, premium grade
LIF-M5219	Mouse	HEK293	Mouse LIF Protein, Tag Free (MALS verified)
LIF-M5227	Mouse	HEK293	Mouse LIF Protein, His Tag (MALS verified)

총 수량6

LIF분자 배경

Leukemia inhibitory factor, or LIF, an interleukin 6 class cytokine, is a protein in cells that affects cell growth and development.Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Removal of LIF pushes stem cells toward differentiation, but they retain their proliferative potential or pluripotency. Therefore LIF is used in mouse embryonic stem cell culture. It is necessary to maintain the stem cells in an undifferentiated state, however genetic manipulation of embryonic stem cells allows for LIF independent growth, notably overexpression of the gene Nanog. LIF is not required for culture of human embryonic stem cells.

LIF분자 별명

LIF,CDF,DIA,HILDA,MLPLI

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Falbikitug	AZD-0171; MSC-1	Phase 2 Clinical	Astrazeneca Plc	Carcinoma, Non-Small-Cell Lung; Ovarian Neoplasms; Pancreatic Neoplasms; Solid tumours	상세
JAB-BX300	JAB-BX300	Phase 2 Clinical	Jacobio Pharmaceuticals Co Ltd	Pancreatic Neoplasms; Solid tumours	상세