언어 선택

Latent TGF-beta 2

Latent TGF-beta 2 분자 정보

영어 이름	Transforming growth factor beta 2	시판 약물 수	0
임상 약물 수	6	표적 별명	TGF-beta-2，BSC-1 Cell Growth Inhibitor，Polyergin，Glioblastoma-Derived T-Cell Suppressor Factor，Cetermin，LDS4，TGFB2，Transforming Growth Factor， Beta 2，Transforming Growth Factor Beta-2 Proprotein，TGF-Beta2，Transforming Growth Factor Beta 2，G-TSF，Transforming Growth Factor beta2，LAP，Prepro-Transforming Growth Factor Beta-2
최고 연구 개발 단계	Phase 3 Clinical

영어 이름	Transforming growth factor beta 2
표적 별명	TGF-beta-2，BSC-1 Cell Growth Inhibitor，Polyergin，Glioblastoma-Derived T-Cell Suppressor Factor，Cetermin，LDS4，TGFB2，Transforming Growth Factor， Beta 2，Transforming Growth Factor Beta-2 Proprotein，TGF-Beta2，Transforming Growth Factor Beta 2，G-TSF，Transforming Growth Factor beta2，LAP，Prepro-Transforming Growth Factor Beta-2
시판 약물 수	0
임상 약물 수	6
최고 연구 개발 단계	Phase 3 Clinical

Latent TGF-beta 2 제품 목록

속성
Protein (1)
제품 라이브러리
온라인 (1)
종
Human (1)
태그
His Tag (1)
마커
Unconjugated (1)

제품 번호	종	발현 시스템	제품 설명	단백질 구조	순도	특성
TG2-H5243	Human	HEK293	Human Latent TGF-beta 2 / TGFB2 Protein, His Tag

총 수량1

Latent TGF-beta 2분자 배경

Transforming growth factor beta 2 ( TGFB2) is also known as TGF-β2, G-TSF, TGFB. is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The TGFB2 protein helps control the growth and division (proliferation) of cells, the process by which cells mature to carry out specific functions (differentiation), cell movement (motility), and the self-destruction of cells (apoptosis). The TGFB2 protein can inhibit the T cell growth by IL-2-dependent. and can inhibit immune surveillance during tumor development, the protein promoting tumor growth with an autocrine manner. TGF-β2 can affect the viability of killer cells and reduce the expression of IL-2, IL-6, IL-10, IFN-γ and other cytokines.TGFB2 plays an important role in controlling the immune system, and shows different activities on different types of cell, or cells at different developmental stages.

Latent TGF-beta 2분자 별명

Latent TGFB2,MGC116892,TGFβ2,TGF-beta2

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Trabedersen	AP 2/09-DS; AP-12009; OT-201; AP-2/09; AP-2/09-DS; OT-101	Phase 3 Clinical	Isarna Therapeutics Gmbh	Astrocytoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Coronavirus Disease 2019 (COVID-19); Diffuse Intrinsic Pontine Glioma; Glioblastoma; Lung Neoplasms; Melanoma; Mesothelioma; Pancreatic Neoplasms; Solid tumours	상세
Bintrafusp alfa	M-7824; GSK-4045154; MSB-0011359C	Phase 3 Clinical	Merck Serono	Anus Neoplasms; Biliary Tract Neoplasms; Brain metastases; Breast Neoplasms; Carcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Small Cell; Carcinoma, Transitional Cell; Cholangiocarcinoma; Colonic Neoplasms; Colorectal Neoplasms; Esthesioneuroblastoma, Olfactory; Gallbladder Neoplasms; Ganglioglioma; Head and Neck Neoplasms; Hematologic Neoplasms; Intestinal Neoplasms; Lung Neoplasms; Lymphoma; Melanoma; Metastatic breast cancer; Microsatellite Instability; Nasopharyngeal Carcinoma; Neoplasm Metastasis; Neoplasms; Neoplasms, Germ Cell and Embryonal; Nose Neoplasms; Oropharyngeal Neoplasms; Pancreatic Neoplasms; Papillomavirus Infections; Penile Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Respiratory papillomatosis; Sarcoma; Sarcoma, Kaposi; Skin Melanoma; Small Cell Lung Carcinoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Thymic epithelial tumor; Thymoma; Thymus Neoplasms; Triple Negative Breast Neop	상세
Nisevokitug	NIS-793	Phase 3 Clinical	Xoma Corp	Adenocarcinoma; Breast Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Kidney Neoplasms; Lung Neoplasms; Myelodysplastic Syndromes; Pancreatic Neoplasms; Polycythemia Vera; Primary Myelofibrosis; Thrombocythemia, Essential	상세
ISTH-0036	ISTH-0036	Phase 2 Clinical	Isarna Therapeutics Gmbh	Diabetic macular oedema; Glaucoma, Open-Angle; Wet Macular Degeneration	상세
Tosposertib phosphate	TU-2218; NCE401; NCE-401	Phase 2 Clinical	TiumBio Co Ltd	Idiopathic Pulmonary Fibrosis; Solid tumours	상세
LP-008	LP-008	Phase 1 Clinical	Lepu Biopharma Co Ltd	Solid tumours	상세