언어 선택

latent GDF-8

latent GDF-8 분자 정보

영어 이름	Growth/differentiation factor 8	시판 약물 수	0
임상 약물 수	6	표적 별명	MSTN，GDF-8，GDF8，Growth Differentiation Factor 8，MSLHP，Myostatin，Growth/Differentiation Factor 8
최고 연구 개발 단계	NDA/BLA

영어 이름	Growth/differentiation factor 8
표적 별명	MSTN，GDF-8，GDF8，Growth Differentiation Factor 8，MSLHP，Myostatin，Growth/Differentiation Factor 8
시판 약물 수	0
임상 약물 수	6
최고 연구 개발 단계	NDA/BLA

제품 문의

latent GDF-8분자 배경

Growth differentiation factor 8 (GDF8), also known as myostatin, is a unique member of the transforming growth factor-β superfamily that is expressed in human granulosa cells and has important roles in regulating a variety of ovarian functions. GDF8 acts as a negative regulator of skeletal muscle growth and differentiation. In addition to the expression in the musculoskeletal system, GDF8 is also expressed in various tissues, including the reproductive system.

latent GDF-8분자 별명

latent GDF-8

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Talditercept alfa	RO-7239361; BMS-986089; RG-6206; BHV-2000	Phase 3 Clinical	Bristol-Myers Squibb Company	Muscular Dystrophy, Duchenne; Neuromuscular Diseases; Muscular Atrophy, Spinal	상세
RO-7204239	GYM-329; RO-7204239; RG-6237; RG-70240	Phase 3 Clinical	F. Hoffmann-La Roche Ltd, Chugai Pharmaceutical Co Ltd	Muscular Dystrophy, Facioscapulohumeral; Muscular Atrophy, Spinal	상세
Trevogrumab	REGN-1033; REGN1033; SAR-391786; GDF8	Phase 2 Clinical	Regeneron Pharmaceuticals Inc	Myositis, Inclusion Body; Obesity; Sarcopenia	상세
AAV1-FS344	AAV1-Follistatin; AAV1-FS344	Phase 2 Clinical	Nationwide Children'S Hospital	Becker muscular dystrophy; Myositis, Inclusion Body; Muscular Dystrophy, Duchenne	상세
KER-065	KER-065; RKER-065	Phase 1 Clinical	Keros Therapeutics Inc	Neuromuscular Diseases; Obesity	상세
HS135	HS-135	Phase 1 Clinical	35Pharma Inc	Hypertension, Pulmonary; Heart Failure, Diastolic; Pulmonary Arterial Hypertension	상세