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Laminin 121 E8

제품 문의

Laminin 121 E8분자 배경

Laminin-121 is one of the α1 chain containing laminins. The α1 chain is detected at the 2-cell stage of the pre-implantation mouse embryo and is subsequently expressed mainly in many epithelial tissues during organogenesis. Laminin-121 showed the highest affinity to α6β1 and α7β1 integrins and furthermore, laminin-121 most effectively supported neurite outgrowth.

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Atacicept	TACI-Ig	Phase 3 Clinical	Zymogenetics Inc	Glomerulonephritis, IGA; Kidney Diseases; Arthritis, Rheumatoid; Multiple Sclerosis; Optic Neuritis; Lupus Nephritis; Urinary Bladder Diseases; Lupus Erythematosus, Systemic	상세
Povetacicept	ALPN-303; ALPN 30x	Phase 3 Clinical		Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Purpura, Thrombocytopenic, Idiopathic; Myasthenia Gravis; Glomerulonephritis, IGA; Sjogren's Syndrome; Glomerulonephritis, Membranous; Lupus Nephritis; Lupus Erythematosus, Systemic; Anemia, Hemolytic, Autoimmune; Inflammation; Cytopenia; Glomerulonephritis	상세
Rozibafusp alfa	AMG-570; MEDI-0700	Phase 2 Clinical	Amgen Inc	Arthritis, Rheumatoid; Lupus Erythematosus, Systemic	상세
Tabalumab	LY-2127399	Phase 2 Clinical	Eli Lilly And Company	Multiple Sclerosis, Relapsing-Remitting; Dermatomyositis; Arthritis, Rheumatoid; Autoimmune Diseases; Scleroderma, Systemic; Multiple Myeloma; Connective Tissue Diseases; Arthritis, Juvenile; Multiple Sclerosis; Lupus Erythematosus, Systemic; Kidney Failure, Chronic; Pemphigus	상세
UBP-1213	UBP-1213	Phase 1 Clinical	Wuhan Huaxin Kangyuan Biomedicine Co Ltd, Shanghai Junshi Biosciences Co Ltd	Lupus Erythematosus, Systemic	상세
Autologous CAR-T cell therapy expressing the BAFF-ligand	LMY-920; LUMT1A22	Phase 1 Clinical	Luminary Therapeutics Inc	Sjogren's Syndrome; Scleroderma, Systemic; Multiple Myeloma; Lupus Erythematosus, Systemic; Lymphoma, Mantle-Cell	상세
UBP1213sc	UBP1213sc	Phase 1 Clinical		Lupus Nephritis; Lupus Erythematosus, Systemic	상세

시판 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	가장 빠른 브랜드 이름	가장 빠른 승인 국가	가장 빠른 적응증	가장 빠른 승인 회사	가장 빠른 승인 날짜	적응증	임상 시험
Telitacicept	RCT-18; RC-18; RCT18; RC18	Approved	RemeGen Co Ltd		Mainland China	Lupus Erythematosus, Systemic	RemeGen Co Ltd	2021-03-09	Myasthenia Gravis; Multiple Sclerosis, Relapsing-Remitting; Glomerulonephritis, IGA; Nephrosis; Immunoglobulin G4-Related Disease; Arthritis, Rheumatoid; Sjogren's Syndrome; Multiple Sclerosis; Lupus Nephritis; Neuromyelitis Optica; Lupus Erythematosus, Systemic	상세
Belimumab	BmAb; GSK-1550188; HGS-1006	Approved	Glaxosmithkline Plc	Benlysta, 倍力腾	United States	Lupus Erythematosus, Systemic	Human Genome Sciences Inc	2011-03-09	Antiphospholipid Syndrome; Leukemia, Lymphocytic, Chronic, B-Cell; Bronchial Diseases; Emphysema; Pulmonary Disease, Chronic Obstructive; Waldenstrom Macroglobulinemia; Hepatitis, Autoimmune; Lymphopenia; Rheumatic Diseases; Sjogren-Larsson Syndrome; Lupus Erythematosus, Systemic; systemic sclerosis-associated interstitial lung disease; Mixed Connective Tissue Disease; Myasthenia Gravis; Glomerulonephritis, Membranous; Lung Diseases, Interstitial; Lupus Nephritis; Graft vs Host Disease; Purpura; Arthritis, Rheumatoid; Scleroderma, Systemic; Myositis; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Granulomatosis with Polyangiitis; Rejection of renal transplantation	상세