Klotho beta
Klotho beta 분자 정보
| 영어 이름 | Klotho beta | 시판 약물 수 | 0 |
| 임상 약물 수 | 3 | 표적 별명 | Klotho Beta，Klotho Beta-Like Protein，B-Klotho，Klotho Beta Like，Beta-Klotho，EC 3.2.1，BKL，BetaKlotho，KLB |
| 최고 연구 개발 단계 | Phase 2 Clinical | ||
| 영어 이름 | Klotho beta |
| 표적 별명 | Klotho Beta，Klotho Beta-Like Protein，B-Klotho，Klotho Beta Like，Beta-Klotho，EC 3.2.1，BKL，BetaKlotho，KLB |
| 시판 약물 수 | 0 |
| 임상 약물 수 | 3 |
| 최고 연구 개발 단계 | Phase 2 Clinical |
Klotho beta 제품 목록
- 속성
Protein (7)
- 제품 라이브러리
온라인 (7)
- 종
Mouse (2)Cynomolgus / Rhesus macaque (1)Rat (1)Human (2)Rhesus macaque (1)
- 태그
His Tag (7)
- 마커
Unconjugated (4)Biotin-labeled (3)
| 제품 번호 | 종 | 발현 시스템 | 제품 설명 | 단백질 구조 | 순도 | 특성 |
|---|---|---|---|---|---|---|
 Human | HEK293 | Human Klotho beta / KLB Protein, His Tag |  |  |  | |
 Mouse | HEK293 | Mouse Klotho beta / KLB Protein, His Tag |  | |  | |
 Cynomolgus / Rhesus macaque | HEK293 | Cynomolgus / Rhesus macaque Klotho beta Protein, His Tag, low endotoxin (BLI verified) |  | | | |
| Human | HEK293 | Biotinylated Human Klotho beta / KLB Protein, His Tag, ultra sensitivity (primary amine labeling) |  | | | |
| Mouse | HEK293 | Biotinylated Mouse Klotho beta / KLB Protein, His Tag, ultra sensitivity (primary amine labeling) (HPLC verified) |  | | ||
 Rat | HEK293 | Rat Klotho beta / KLB Protein, His Tag |  | | ||
 Rhesus macaque | HEK293 | Biotinylated Rhesus macaque Klotho beta / KLB Protein, His Tag, ultra sensitivity (primary amine labeling) |  | | |
총 수량7
- 1
Klotho beta분자 배경
KLB (Klotho Beta) is a Protein Coding gene. Among its related pathways are RET signaling and HIV Life Cycle. GO annotations related to this gene include hydrolase activity, hydrolyzing O-glycosyl compounds and fibroblast growth factor binding. An important paralog of this gene is KL. Klotho Beta is a regulator in multiple metabolic processes, while its role in cancer remains unclear. We found the expression of βKlotho was down-regulated in human hepatocellular carcinoma tissues compared with that in paired adjacent non-tumourous liver tissues. Hepatoma cells also showed decreased expression of βKlotho compared with normal hepatocyte cells. Reintroduction of βKlotho into hepatoma cells inhibited their proliferation.
Klotho beta분자 별명
betaKlotho,beta-klotho,BKL,KLB,klotho beta like,klotho beta-like protein
임상 약물 정보
| 영어 이름 | 연구 코드 | 연구 개발 단계 | 회사 | 적응증 | 임상 시험 |
|---|---|---|---|---|---|
| NGM-313 | NGM-313; MK-3655 | Phase 2 Clinical | NGM Biopharmaceuticals Inc | Hepatitis; Metabolic Dysfunction-Associated Steatotic Liver Disease; Obesity | 상세 |
| JMT-202 | JMT202; JMT-202 | Phase 2 Clinical | Shanghai Jmt-Bio Inc | Hypertriglyceridemia | 상세 |
| DR-10624 | DR-10624; DR10624 | Phase 2 Clinical | Zhejiang Doer Biologics Corp | Diabetes Mellitus; Diabetes Mellitus, Type 2; Hypertriglyceridemia; Metabolic Dysfunction-Associated Steatotic Liver Disease; Metabolic Syndrome; Obesity; Overweight | 상세 |
- 분자 정보
- 제품 목록
- 임상 약물 정보