언어 선택

Klotho beta

Klotho beta 분자 정보

영어 이름	Klotho beta	시판 약물 수	0
임상 약물 수	3	표적 별명	Klotho Beta，Klotho Beta-Like Protein，B-Klotho，Klotho Beta Like，Beta-Klotho，EC 3.2.1，BKL，BetaKlotho，KLB
최고 연구 개발 단계	Phase 2 Clinical

영어 이름	Klotho beta
표적 별명	Klotho Beta，Klotho Beta-Like Protein，B-Klotho，Klotho Beta Like，Beta-Klotho，EC 3.2.1，BKL，BetaKlotho，KLB
시판 약물 수	0
임상 약물 수	3
최고 연구 개발 단계	Phase 2 Clinical

Klotho beta 제품 목록

속성
Protein (7)
제품 라이브러리
온라인 (7)
종
Mouse (2)Cynomolgus / Rhesus macaque (1)Rat (1)Human (2)Rhesus macaque (1)
태그
His Tag (7)
마커
Unconjugated (5)Biotin-labeled (2)

제품 번호	종	발현 시스템	제품 설명
HOT KLB-H52H4	Human	HEK293	Human Klotho beta / KLB Protein, His Tag
HOT KLB-M52H7	Mouse	HEK293	Mouse Klotho beta / KLB Protein, His Tag
HOT KLB-R52H8	Cynomolgus / Rhesus macaque	HEK293	Cynomolgus / Rhesus macaque Klotho beta Protein, His Tag (BLI verified)
KLB-H82H3	Human	HEK293	Biotinylated Human Klotho beta / KLB Protein, His Tag, ultra sensitivity (primary amine labeling)
KLB-M52H3	Mouse	HEK293	Biotinylated Mouse Klotho beta / KLB Protein, His Tag, ultra sensitivity (primary amine labeling) (HPLC verified)
KLB-R52H6	Rat	HEK293	Rat Klotho beta / KLB Protein, His Tag
KLB-R82H3	Rhesus macaque	HEK293	Biotinylated Rhesus macaque Klotho beta / KLB Protein, His Tag, ultra sensitivity (primary amine labeling)

총 수량7

Klotho beta분자 배경

KLB (Klotho Beta) is a Protein Coding gene. Among its related pathways are RET signaling and HIV Life Cycle. GO annotations related to this gene include hydrolase activity, hydrolyzing O-glycosyl compounds and fibroblast growth factor binding. An important paralog of this gene is KL. Klotho Beta is a regulator in multiple metabolic processes, while its role in cancer remains unclear. We found the expression of βKlotho was down-regulated in human hepatocellular carcinoma tissues compared with that in paired adjacent non-tumourous liver tissues. Hepatoma cells also showed decreased expression of βKlotho compared with normal hepatocyte cells. Reintroduction of βKlotho into hepatoma cells inhibited their proliferation.

Klotho beta분자 별명

betaKlotho,beta-klotho,BKL,KLB,klotho beta like,klotho beta-like protein

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
NGM-313	NGM-313; MK-3655	Phase 2 Clinical	NGM Biopharmaceuticals Inc	Hepatitis; Metabolic Dysfunction-Associated Steatotic Liver Disease; Obesity	상세
JMT-202	JMT202; JMT-202	Phase 2 Clinical	Shanghai Jmt-Bio Inc	Hypertriglyceridemia	상세
DR-10624	DR-10624; DR10624	Phase 2 Clinical	Zhejiang Doer Biologics Corp	Diabetes Mellitus; Diabetes Mellitus, Type 2; Hypertriglyceridemia; Metabolic Dysfunction-Associated Steatotic Liver Disease; Metabolic Syndrome; Obesity; Overweight	상세