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Jagged 1

Jagged 1

Jagged 1 분자 정보

Molecule Name
Protein jagged-1
분자 별명
CD339,JAG1,Jagged1,hJ1,JAGL1
Drug Development Progress
임상 약물 수2
시판 약물 수0
최고 연구 개발 단계Phase 1 Clinical
표적 별명
AHD，AWS，AGS，Jagged-1 Protein，Jagged1，Protein jagged-1，JAG1，Jagged 1，JAGL1，Alagille Syndrome，CD339，AGS1，DCHE，Jagged Canonical Notch Ligand 1，hJ1，CD339 Antigen
분자 배경
Protein jagged-1 (JAG1) is also known as Jagged1, hJ1, JAGL1 and CD339, which is a single-pass type I membrane protein containing one DSL domain and 15 EGF-like domains. JAG1 is widely expressed in adult and fetal tissues,the expression of JAG1 is up-regulated in cervical squamous cell carcinoma and also expressed in bone marrow cell line HS-27a.JAG1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. JAG1 is involved in early and late stages of mammalian cardiovascular development. JAG1 inhibits myoblast differentiation by similarity and enhances fibroblast growth factor-induced angiogenesis (in vitro).

Jagged 1 제품 목록

Species
  • Human（1）
Tag
  • His Tag（1）
Host
  • HEK293（1）
Conjugate
  • Unconjugated（1）
Grade
  • RUO（1）
Low Endotoxin
  • Yes（1）
분자Cat. No.Product Name종Host구조순도Activity규격 및 가격
Jagged 1
JA1-H52H9
Human Jagged 1 / JAG1 Protein, His Tag, low endotoxin
Human
HEK293
SDS-PAGE
SPR

$300.00

50ug
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임상 약물 정보

영어 이름연구 코드연구 개발 단계회사적응증임상 시험
AMG-430AMG-430Phase 1 ClinicalAmgen Inc
Cystic Fibrosis; Pulmonary Disease, Chronic Obstructive
상세
ART-104 (Arnatar Therapeutics)ART-104; ART104ClinicalSuzhou Arnatar Therapeutics Co Ltd
Alagille Syndrome
상세
Customer Reviews
  • n***l2026-08-08
    Human Jagged 1 / JAG1 Protein, His Tag, low endotoxin
    This product genuinely is the best and i have been using it for a while and it's been nothing but amaizng
  • V***s2021-08-25
    Human Jagged 1 / JAG1 Protein, His Tag, low endotoxin
    We are a company in the filed of Antibody Discovery and engineering.. Jagged 1/JAG1 His tag shelps us greatly in searching and characterization of specific antibodies,and detectors. It is a great quality product, and its efficacy is always reliable. It also comes with a certification of analysis, which has very insighful information. We use Acrobiosystems products, because they are easy to order, reliable and fast delivery. Thank you! Victor G.