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Integrin alpha 3 beta 1

Integrin alpha 3 beta 1 Overview

English Name	Integrin alpha 3/beta 1	Approved Drugs	0
Drugs in Clinical Trials	1	Target Synonym
Highest Development Stage	Phase 1 Clinical

English Name	Integrin alpha 3/beta 1
Target Synonym
Approved Drugs	0
Drugs in Clinical Trials	1
Highest Development Stage	Phase 1 Clinical

Integrin alpha 3 beta 1 Product List

Product Category
Protein (3)
Product Status
Launched (3)
Species
Human (1)Rat (1)Cynomolgus (1)
Tag
His Tag (3)
Conjugate
Unconjugated (3)

Cat. No.	Species	Host	Product Description
IT1-H52Wc	Human	HEK293	Human Integrin alpha 3 beta 1 (ITGA3&ITGB1) Heterodimer Protein, His Tag&Tag Free, low endotoxin (MALS verified)
IT1-C52W6	Cynomolgus	HEK293	Cynomolgus Integrin alpha 3 beta 1 (ITGA3&ITGB1) Heterodimer Protein, His Tag&Tag Free
IT1-R53Wb	Rat	CHO	Rat Integrin alpha 3 beta 1 (ITGA3&ITGB1) Heterodimer Protein, His Tag&Tag Free (MALS verified)

Total: 3

Integrin alpha 3 beta 1 Background

Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.