IL23A & IL12B
IL23A & IL12B 분자 정보
| 영어 이름 | Interleukin-12 subunit beta | 시판 약물 수 | 8 |
| 임상 약물 수 | 2 | 표적 별명 | IL-12B，NK cell stimulatory factor chain 2，IL12B，Interleukin 12B，Interleukin 12B (Natural Killer Cell Stimulatory Factor 2， Cytotoxic Lymphocyte Maturation Factor 2， P40)，Cytotoxic Lymphocyte Maturation Factor 40 KDa Subunit，Interleukin-12 Beta Chain，Interleukin 12， P40，IL12， Subunit P40，CLMF P40，NKSF2，Cytotoxic Lymphocyte Maturation Factor 2， P40，Interleukin-12 Subunit Beta，CLMF2，IMD28，IMD29，CLMF，NKSF，Interleukin-12 Subunit p40，Natural Killer Cell Stimulatory Factor， 40 KD Subunit，IL-12 Subunit P40，Natural Killer Cell Stimulatory Factor-2 |
| 최고 연구 개발 단계 | Approved | ||
| 영어 이름 | Interleukin-12 subunit beta |
| 표적 별명 | IL-12B，NK cell stimulatory factor chain 2，IL12B，Interleukin 12B，Interleukin 12B (Natural Killer Cell Stimulatory Factor 2， Cytotoxic Lymphocyte Maturation Factor 2， P40)，Cytotoxic Lymphocyte Maturation Factor 40 KDa Subunit，Interleukin-12 Beta Chain，Interleukin 12， P40，IL12， Subunit P40，CLMF P40，NKSF2，Cytotoxic Lymphocyte Maturation Factor 2， P40，Interleukin-12 Subunit Beta，CLMF2，IMD28，IMD29，CLMF，NKSF，Interleukin-12 Subunit p40，Natural Killer Cell Stimulatory Factor， 40 KD Subunit，IL-12 Subunit P40，Natural Killer Cell Stimulatory Factor-2 |
| 시판 약물 수 | 8 |
| 임상 약물 수 | 2 |
| 최고 연구 개발 단계 | Approved |
IL23A & IL12B 제품 목록
- 속성
Protein (16)
- 제품 라이브러리
온라인 (16)
- 종
Human (3)Human & Mouse (1)Mouse (2)Cynomolgus & Mouse (1)Human & Rat (2)Cynomolgus (2)Rat (1)Rabbit (1)Human | Alpaca (1)Golden Hamster (1)Guinea pig (1)
- 태그
His Tag (12)His Tag & Avi Tag (3)Tag Free (1)
- 마커
Unconjugated (13)Biotin-labeled (3)
총 수량16
- 1
- 2
IL23A & IL12B분자 배경
Interleukin-23 subunit alpha (IL-23 alpha) can associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
IL23A & IL12B분자 별명
IL-23 alpha & IL-12 beta
임상 약물 정보
| 영어 이름 | 연구 코드 | 연구 개발 단계 | 회사 | 적응증 | 임상 시험 |
|---|---|---|---|---|---|
| RO-7837195 | RO-7837195; RO7837195 | Phase 2 Clinical | Genentech Inc | Colitis, Ulcerative | 상세 |
| PF-07261271 | RG-6730; PF-07261271 | Phase 2 Clinical | Pfizer Inc | Inflammatory Bowel Diseases | 상세 |
시판 약물 정보
| 영어 이름 | 연구 코드 | 연구 개발 단계 | 회사 | 가장 빠른 브랜드 이름 | 가장 빠른 승인 국가 | 가장 빠른 적응증 | 가장 빠른 승인 회사 | 가장 빠른 승인 날짜 | 적응증 | 임상 시험 |
|---|---|---|---|---|---|---|---|---|---|---|
| Ustekinumab biosimilar (Bio-Thera) | BAT-2206 | Approved | Bio-Thera Solutions Ltd | STARJEMZA, Usymro | United States | Plaque psoriasis; Crohn Disease; Colitis, Ulcerative; Arthritis, Psoriatic | Bio-Thera Solutions Ltd | 2025-05-22 | Arthritis, Psoriatic; Autoimmune Diseases; Colitis, Ulcerative; Crohn Disease; Plaque psoriasis; Psoriasis | 상세 |
| Ustekinumab | C-340; CNTO-1275 | Approved | Johnson & Johnson Innovative Medicine | Stelara, 喜达诺 | United States | Plaque psoriasis | Janssen Biotech Inc | 2009-09-25 | Arthritis, Juvenile; Arthritis, Psoriatic; Colitis, Ulcerative; Common Variable Immunodeficiency; Crohn Disease; Dermatitis, Atopic; Dermatomyositis; Diabetes Mellitus, Type 1; Hidradenitis Suppurativa; Ichthyosis; Inflammatory Bowel Diseases; Liver Cirrhosis, Biliary; Lupus Erythematosus, Systemic; Multiple Sclerosis; Palmoplantar pustulosis; Pediatric Crohn's disease; Plaque psoriasis; Polymyositis; Pouchitis; Psoriasis; Sjogren's Syndrome; Spondylitis, Ankylosing; Takayasu Arteritis; Type I Leukocyte Adhesion Defect; Uveitis | 상세 |
| Ebdarokimab | AK-101; AK101 | Approved | 爱达罗 | Mainland China | Plaque psoriasis | Zhongshan Akeso Biopharma Co Ltd | 2025-04-15 | Arthritis, Psoriatic; Colitis, Ulcerative; Crohn Disease; Plaque psoriasis; Psoriasis | 상세 | |
| Ustekinumab Biosimilar(Celltrion) | CT-P43 | Approved | Celltrion Inc | Steqeyma, Steqeyma IV, Qoyvolma | Canada | Arthritis, Psoriatic; Crohn Disease; Plaque psoriasis | Celltrion Inc | 2024-08-01 | Arthritis, Psoriatic; Colitis, Ulcerative; Crohn Disease; Plaque psoriasis; Psoriasis | 상세 |
| Ustekinumab biosimilar (Biocon) | Bmab 1200 | Approved | Biocon Biologics Ltd | Yesintek | United States | Colitis, Ulcerative; Crohn Disease; Arthritis, Psoriatic | Biocon Biologics Inc | 2024-11-29 | Arthritis, Psoriatic; Colitis, Ulcerative; Crohn Disease; Plaque psoriasis; Psoriasis | 상세 |
| Ustekinumab biosimilar (Alvotech) | AVT04; AVT-04 | Approved | Alvotech hf | Jamteki, Uzpruvo, SELARSDI™, JamtekiTM, Ustekinumab BS (F) | Japan | Arthritis, Psoriatic; Psoriasis | Fuji Pharma Co Ltd | 2023-09-25 | Arthritis, Psoriatic; Colitis, Ulcerative; Crohn Disease; Plaque psoriasis; Psoriasis | 상세 |
| Ustekinumab biosimilar (Samsung Bioepis) | SB-17; SB17 | Approved | Samsung Bioepis Co Ltd | Pyzchiva, Eksunbi | EU | Crohn Disease; Colitis, Ulcerative | Samsung Bioepis Nl Bv | 2024-04-19 | Arthritis, Psoriatic; Colitis, Ulcerative; Crohn Disease; Gastrointestinal Diseases; Inflammation; Plaque psoriasis; Psoriasis; Rheumatic Diseases; Skin Diseases | 상세 |
| Ustekinumab biosimilar (Amgen) | ABP-654; AMG-654 | Approved | Amgen Inc | Wezlana, WEZLANA, wezenla, WEZENLA | United States | Crohn Disease; Colitis, Ulcerative; Arthritis, Psoriatic; Plaque psoriasis | Amgen Inc | 2023-10-31 | Arthritis, Psoriatic; Colitis, Ulcerative; Crohn Disease; Plaque psoriasis; Psoriasis | 상세 |
- 분자 정보
- 제품 목록
- 시판 약물 정보
- 임상 약물 정보