언어 선택

IL-8

IL-8 분자 정보

영어 이름	Interleukin-8	시판 약물 수	1
임상 약물 수	6	표적 별명	IL8/NAP1 form VI，T-cell chemotactic factor，GCP/IL-8 protein III，IL8/NAP1 form II，GCP/IL-8 protein II，(Ala-IL-8)77，Emoctakin，IL8/NAP1 form IV，LYNAP，IL8/NAP1 form III，IL8/NAP1 form V，GCP/IL-8 protein I，Neutrophil-Activating Peptide 1，Interleukin 8，GCP-1，MDNCF，NAP-1，IL8，Beta Endothelial Cell-Derived Neutrophil Activating Peptide，Lung Giant Cell Carcinoma-Derived Chemotactic Protein，Lymphocyte Derived Neutrophil Activating Peptide，Alveolar Macrophage Chemotactic Factor I，Tumor Necrosis Factor-Induced Gene 1，Small Inducible Cytokine Subfamily B， Member 8，Beta-Thromboglobulin-Like Protein，GCP1，LECT，LUCT，NAP1，IL-8，Interleukin-8，AMCF-I，SCYB8，Neutrophil-Activating Protein 1，B-ENAP，3-10C，K60，TSG-1，C-X-C Motif Chemokine Ligand 8，Monocyte-Derived Neutrophil Chemotactic Factor，Monocyte-Derived Neutrophil-Activating Peptide，Granulocyte Chemotactic Protein 1，Chemokine (C-X-C Motif) Ligand 8，(Ser-IL-8)72，Neutrophil-activating factor，MDNCF-c，C-X-C motif chemokine 8，Lymphocyte-derived neutrophil-activating factor，Protein 3-10C，IL-8(1-77)，NAF，GCP/IL-8 protein VI，GCP/IL-8 protein IV，IL8/NAP1 form I，MONAP，MDNCF-b，GCP/IL-8 protein V，CXCL8
최고 연구 개발 단계	Approved

영어 이름	Interleukin-8
표적 별명	IL8/NAP1 form VI，T-cell chemotactic factor，GCP/IL-8 protein III，IL8/NAP1 form II，GCP/IL-8 protein II，(Ala-IL-8)77，Emoctakin，IL8/NAP1 form IV，LYNAP，IL8/NAP1 form III，IL8/NAP1 form V，GCP/IL-8 protein I，Neutrophil-Activating Peptide 1，Interleukin 8，GCP-1，MDNCF，NAP-1，IL8，Beta Endothelial Cell-Derived Neutrophil Activating Peptide，Lung Giant Cell Carcinoma-Derived Chemotactic Protein，Lymphocyte Derived Neutrophil Activating Peptide，Alveolar Macrophage Chemotactic Factor I，Tumor Necrosis Factor-Induced Gene 1，Small Inducible Cytokine Subfamily B， Member 8，Beta-Thromboglobulin-Like Protein，GCP1，LECT，LUCT，NAP1，IL-8，Interleukin-8，AMCF-I，SCYB8，Neutrophil-Activating Protein 1，B-ENAP，3-10C，K60，TSG-1，C-X-C Motif Chemokine Ligand 8，Monocyte-Derived Neutrophil Chemotactic Factor，Monocyte-Derived Neutrophil-Activating Peptide，Granulocyte Chemotactic Protein 1，Chemokine (C-X-C Motif) Ligand 8，(Ser-IL-8)72，Neutrophil-activating factor，MDNCF-c，C-X-C motif chemokine 8，Lymphocyte-derived neutrophil-activating factor，Protein 3-10C，IL-8(1-77)，NAF，GCP/IL-8 protein VI，GCP/IL-8 protein IV，IL8/NAP1 form I，MONAP，MDNCF-b，GCP/IL-8 protein V，CXCL8
시판 약물 수	1
임상 약물 수	6
최고 연구 개발 단계	Approved

IL-8 제품 목록

속성
Protein (5)Kits (3)
제품 라이브러리
온라인 (7)연구 중 (1)
종
Human (7)Rhesus macaque (1)
태그
His Tag (2)Fc Tag (1)His Tag & Avi Tag (1)- (3)Tag Free (1)
마커
Unconjugated (4)Biotin-labeled (1)- (3)

제품 번호	종	발현 시스템	제품 설명
HOT CRS-B004	Human	-	Human IL-8 ELISA Kit
HOT IL8-H5217	Human	HEK293	Human IL-8 / CXCL8 Protein, premium grade
HOT IL8-H52H3	Human	HEK293	Human IL-8 / CXCL8 Protein, His Tag
HOT IL8-H82H3	Human	HEK293	Biotinylated Human IL-8 protein, His,Avitag™
HOT IL8-C52H4	Rhesus macaque	HEK293	Rhesus macaque IL-8 / CXCL8 Protein, His Tag (MALS verified)
CEA-C004	Human	-	Human IL-8 ELISA Kit, PRO
FCSh-015	Human	-	Human IL-8 Detection Kit (Flow Cytometry Bead Assay)
IL8-H5258	Human	HEK293	Human IL-8 / CXCL8 Protein, Fc Tag

총 수량8

IL-8분자 배경

Interleukin 8 (IL8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells. There are many receptors on the surface membrane capable of binding IL-8, the most frequently studied types are the G protein-coupled serpentine receptors CXCR1 and CXCR2. Expression and affinity for IL-8 differs between the two receptors (CXCR1 > CXCR2). IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.

IL-8분자 별명

CXCL8,GCP1,IL8,LECT,LUCT,LYNAP,MDNCF,MONAP,NAF,NAP-1

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Ensereptide	PXL-01	Phase 3 Clinical	Promore Pharma	Cicatrix; Post-surgical adhesions; Tissue Adhesions	상세
Cinainu		Phase 3 Clinical	Legacy Healthcare (Switzerland) Sa	Alopecia Areata	상세
Sodium Hypochlorite		Phase 3 Clinical		Cystic Fibrosis; Dental Pulp Necrosis; Fibrosis; Infections; Pain; Pain, Postoperative; Pulpitis	상세
Adakitug	BMS-986253; MDX-018	Phase 2 Clinical	Bristol-Myers Squibb Company, Genmab A/S, Medarex Inc	Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Coronavirus Disease 2019 (COVID-19); Hematologic Neoplasms; Melanoma; Myelodysplastic Syndromes; Neoplasms; Prostatic Neoplasms; Solid tumours; Squamous Cell Carcinoma of Head and Neck	상세
AMY-109	AMY-109; AMY109	Phase 2 Clinical	Chugai Pharmaceutical Co Ltd	Endometriosis; Solid tumours	상세
AC-701	AC-701	Phase 2 Clinical	Twi Pharmaceuticals Inc	Exanthema; Rosacea	상세

시판 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	가장 빠른 브랜드 이름	가장 빠른 승인 국가	가장 빠른 적응증	가장 빠른 승인 회사	가장 빠른 승인 날짜	적응증	임상 시험
Mouse monoclonal antibody against human interleukin-8 cream		Approved	Dalian Asia Space Pharmaceutical Co Ltd, Dongguan Hongyuan Yishi Biotechnology Pharmaceutical Co Ltd	恩博克	Mainland China	Eczema; Psoriasis	Dalian Asia Space Pharmaceutical Co Ltd	2001-04-10	Eczema; Psoriasis	상세