언어 선택

IL-7 R alpha & TSLP R

IL-7 R alpha & TSLP R 분자 정보

영어 이름	Interleukin-7 receptor subunit alpha	시판 약물 수	0
임상 약물 수	8	표적 별명	Interleukin-7 receptor subunit alpha，Interleukin 7 Receptor Isoform H5-6，CDw127，IL-7R subunit alpha，IL-7RA，IL-7 receptor subunit alpha，CD127 Antigen，IL-7R-Alpha，Interleukin 7 Receptor Alpha Chain，CD127，IL7RA，ILRA，Interleukin-7 Receptor alpha Subunit
최고 연구 개발 단계	Phase 2 Clinical

영어 이름	Interleukin-7 receptor subunit alpha
표적 별명	Interleukin-7 receptor subunit alpha，Interleukin 7 Receptor Isoform H5-6，CDw127，IL-7R subunit alpha，IL-7RA，IL-7 receptor subunit alpha，CD127 Antigen，IL-7R-Alpha，Interleukin 7 Receptor Alpha Chain，CD127，IL7RA，ILRA，Interleukin-7 Receptor alpha Subunit
시판 약물 수	0
임상 약물 수	8
최고 연구 개발 단계	Phase 2 Clinical

IL-7 R alpha & TSLP R 제품 목록

속성
Protein (3)Cell (1)Kits (1)
제품 라이브러리
온라인 (5)
종
Human (4)Mouse (1)
태그
Fc Tag (3)- (2)
마커
Unconjugated (3)- (2)

제품 번호	종	발현 시스템	제품 설명
HOT CHEK-ATF045	Human	HEK293	Human TSLP R (Luc) HEK293 Reporter Cell
HOT EP-129	Human	-	TSLP [Biotinylated] : IL-7Rα & TSLP R Inhibitor Screening ELISA Kit
HOT ILR-H5255	Human	HEK293	Human IL-7 R alpha&TSLP R Heterodimer Protein, Fc Tag&Fc Tag, low endotoxin (MALS verified)
ILR-H525x	Human	HEK293	Human IL-7 R alpha&TSLP R Heterodimer Protein, Fc Tag&Fc Tag
ILR-M5257	Mouse	HEK293	Mouse IL-7 R alpha&TSLP R Heterodimer Protein, Fc Tag&Fc Tag

총 수량5

IL-7 R alpha & TSLP R분자 배경

TSLP is a pleiotropic cytokine originally characterized as a lymphocyte growth factor. Thymic stromal lymphopoietin (TSLP) is overexpressed in the airways of severe asthmatics and is an upstream cytokine that orchestrates inflammatory responses in asthma. Human TSLP exerts its biological activities by binding to a high-affinity heteromeric receptor complex composed of TSLPR and IL- 7 receptor and initiates signaling in cells co-expressing TSLPR and IL-7R.

IL-7 R alpha & TSLP R분자 별명

IL7Ra,CD127,TSLP R,CRLF2,IL-XR,ILXR,p2RY8,CRLF2 fusion,TSLP receptor,TSLPR,CRL2,CRLF2Y,Cytokine receptor-like 2

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
CYT-107	CYT-107; CYT-99-007; rhIL-7	Phase 2 Clinical	Revimmune Inc	Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Catheter-Related Infections; Coronavirus Disease 2019 (COVID-19); Hepatitis B, Chronic; Hepatitis C; HIV Infections; Kidney Neoplasms; Leukemia, Myelogenous, Chronic; Leukemia, Myeloid, Acute; Lymphopenia; Metastatic breast cancer; Multiple Myeloma; Mycobacterium Infections, Nontuberculous; Myelodysplastic Syndromes; Myeloproliferative Disorders; Neuroblastoma; Neuroectodermal Tumors, Primitive, Peripheral; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rhabdomyosarcoma, Alveolar; Rhabdomyosarcoma, Embryonal; Sarcoma; Sarcoma, Kaposi; Sepsis; Shock, Septic; Skin Melanoma; T-Lymphocytopenia, Idiopathic CD4-Positive; Ureteral Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Urologic Neoplasms	상세
Lusvertikimab	OSE-127; S-95011; Effi-7; OSE-217	Phase 2 Clinical	Effimune	Colitis, Ulcerative; Sjogren's Syndrome	상세
Efineptakin alfa	TJ-107; GX-I7; NT-I7	Phase 2 Clinical	Gannex Pharma Co Ltd	Astrocytoma; Breast Neoplasms; Carcinoma, Merkel Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Colorectal Neoplasms; Coronavirus Disease 2019 (COVID-19); Esophageal Neoplasms; Glioblastoma; Glioma; Gliosarcoma; HIV Infections; Hypopharyngeal Neoplasms; Laryngeal Neoplasms; Leukoencephalopathy, Progressive Multifocal; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Lymphopenia; Melanoma; Multiple Myeloma; Oropharyngeal Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Papillomavirus Infections; Plasmablastic Lymphoma; Prostatic Neoplasms, Castration-Resistant; Sarcoma, Kaposi; Small Cell Lung Carcinoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms	상세
ASP-9801	ASP-9801	Phase 1 Clinical	Astellas Pharma Inc	Neoplasm Metastasis; Neoplasms; Solid tumours	상세
PF-06342674	RN-168; PF-6342674; PF-06342674; ZB-168	Phase 1 Clinical	Pfizer Inc	Diabetes Mellitus, Type 1; Multiple Sclerosis	상세
CD19-IL7Ra CAR-T cells therapy (Chulalongkorn University)	CMD-63; CMD63	Phase 1 Clinical	Chulalongkorn University	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma	상세
Loco-regional B7H3 IL-7Ra CAR T Cell therapy(Chulalongkorn University)		Phase 1 Clinical	Chulalongkorn University, King Chulalongkorn Memorial Hospital	Brain Neoplasms; Diffuse Intrinsic Pontine Glioma; Neoplasms; Solid tumours	상세
MDK-703	MDK-703	Phase 1 Clinical	Medikine Inc	Solid tumours	상세