언어 선택

IL-6

IL-6 분자 정보

영어 이름	Interleukin-6	시판 약물 수	5
임상 약물 수	22	표적 별명	CTL Differentiation Factor，Interleukin 6 (Interferon， Beta 2)，HSF，B-cell stimulatory factor 2，Interferon beta-2，IL6，IFNB2，IL-6，Interleukin-6，Interleukin 6，Hybridoma Growth Factor，IFN-Beta-2，BSF-2，CDF，B-Cell Differentiation Factor，Interferon， Beta 2，Interleukin BSF-2，BSF2，HGF
최고 연구 개발 단계	Approved

영어 이름	Interleukin-6
표적 별명	CTL Differentiation Factor，Interleukin 6 (Interferon， Beta 2)，HSF，B-cell stimulatory factor 2，Interferon beta-2，IL6，IFNB2，IL-6，Interleukin-6，Interleukin 6，Hybridoma Growth Factor，IFN-Beta-2，BSF-2，CDF，B-Cell Differentiation Factor，Interferon， Beta 2，Interleukin BSF-2，BSF2，HGF
시판 약물 수	5
임상 약물 수	22
최고 연구 개발 단계	Approved

IL-6 제품 목록

속성
Protein (10)Kits (6)
제품 라이브러리
온라인 (14)연구 중 (2)
종
Human (10)Mouse (4)Cynomolgus (2)
태그
Tag Free (4)His Tag (3)His Tag & Avi Tag (3)- (6)
마커
Unconjugated (6)Biotin-labeled (4)- (6)

제품 번호	종	발현 시스템	제품 설명
HOT CRS-B001	Human	-	Human IL-6 ELISA Kit
HOT GMP-L06H27	Human	HEK293	GMP Human IL-6 Protein
HOT IL6-H4218	Human	HEK293	Human IL-6 Protein, premium grade
HOT IL6-H5243	Human	HEK293	Human IL-6 Protein, His Tag, low endotoxin (MALS verified)
HOT IL6-H82Q9	Human	HEK293	Biotinylated Human IL-6 Protein, Avitag™,His Tag (MALS verified)
HOT IL6-C5249	Cynomolgus	HEK293	Cynomolgus IL-6 Protein, His Tag, low endotoxin (MALS verified)
CRS-A005	Human	-	resDetect™ Human Interleukin-6 (IL-6) ELISA Kit (Residue Testing)
EP-146	Human	-	IL-6 [Biotinylated] : IL-6 R alpha Inhibitor Screening ELISA Kit
FCSh-003	Human	-	Human IL-6 Detection Kit (Flow Cytometry Bead Assay)
IL6-H5115	Human	E. coli	Human IL-6 Protein (E. coli), premium grade

총 수량16

IL-6분자 배경

Interleukin 6 (IL-6) is also known as HGF, BSF2,HSF, IFNB2 and IL-6, originally identified as a B cell differentiation factor, is a multifunctional cytokine that regulates immune responses, hematopoiesis, acute phase responses, and inflammatory reactions.It is secreted by T cells, macrophages , monocytes, fibroblasts,endothelial cells,et.al. to stimulate immune response to trauma, especially burns or other tissue damage leading to inflammation. Interleukin 6 has been shown to interact with interleukin-6 receptor and glycoprotein. IL-6 is relevant to many disease processes such as diabetes,atherosclerosis, depression,Alzheimer's Disease,systemic,lupus erythematosus,prostate cancer and rheumatoid arthritis. Advanced/metastatic cancer patients have higher levels of IL-6 in their blood.Hence there is an interest in developing anti-IL-6 agents as therapy against many of these diseases.

IL-6분자 별명

IL6,Interleukin-6,BSF2,HSF,IFNB2

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Ensereptide	PXL-01	Phase 3 Clinical	Promore Pharma	Cicatrix; Post-surgical adhesions; Tissue Adhesions	상세
Olokizumab	CDP-6038; Anti-IL6-UCB	Phase 3 Clinical	Ucb	Arthritis; Arthritis, Rheumatoid; Coronavirus Disease 2019 (COVID-19); Crohn Disease; Lung Diseases, Interstitial	상세
Efprezimod alfa	CD24-Fc; HAS-CD24; CD24-Fc-IgG; MK-7110; MK7110	Phase 3 Clinical	Oncoimmune Inc	Coronavirus Disease 2019 (COVID-19); Dyslipidemias; Graft vs Host Disease; Hematopoietic stem cell transplantation (HSCT); HIV Infections; Leukemia; Leukemia, Myeloid, Acute; Melanoma; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Solid tumours	상세
Ziltivekimab	EX-6018; MEDI-5117; WBP-216; COR-001; NN6018	Phase 3 Clinical	Medimmune Llc	Anemia; Arthritis, Rheumatoid; Atherosclerosis; Cardiovascular Diseases; Coronary Artery Disease; Heart Failure; Inflammation; Myocardial Infarction; Renal Insufficiency, Chronic	상세
Clazakizumab	BMS-645429; ALD518-003; ALD-518; CSL300; BMS-945429; CSL-300	Phase 3 Clinical	Alder Biopharmaceuticals	Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; Cachexia; Carcinoma, Non-Small-Cell Lung; Cardiovascular Diseases; Cardiovascular Infections; Coronavirus Disease 2019 (COVID-19); Crohn Disease; Diabetes Mellitus; Fatigue; Frailty; Graft vs Host Disease; Inflammation; Kidney Failure, Chronic; Myocardial Infarction; Rejection of organ transplantation; Stomatitis	상세
Tabirafusp tedromer	KSI-501ABC; KSI-501	Phase 3 Clinical	Kodiak Sciences Inc	Diabetic macular oedema; Retinal Diseases; Uveitis; Wet Macular Degeneration	상세
Tabirafusp alfa	KSI-101; KSI-501P	Phase 3 Clinical	Kodiak Sciences Inc	Macular Edema	상세
Bezisterim	HE-3286; NE-3107	Phase 3 Clinical	Harbor Therapeutics Inc	Alzheimer Disease; Arthritis, Rheumatoid; Brain Injuries, Traumatic; Colitis, Ulcerative; Diabetes Mellitus, Type 2; Insulin Resistance; Parkinson Disease; Post-Acute COVID-19 Syndrome	상세
Vamikibart	RO-7200220; RG-6179; EBI-031	Phase 3 Clinical	Sesen Bio Inc	Diabetic macular oedema; Macular Edema	상세
Sodium Hypochlorite		Phase 3 Clinical		Cystic Fibrosis; Dental Pulp Necrosis; Fibrosis; Infections; Pain; Pain, Postoperative; Pulpitis	상세
Pacibekitug	PF-04236921; TOUR006; TOUR-006; PF-4236921	Phase 2 Clinical	Pfizer Inc	Arthritis, Rheumatoid; Cardiovascular Diseases; Crohn Disease; Graves Ophthalmopathy; Lupus Erythematosus, Systemic; Renal Insufficiency, Chronic	상세
Sirukumab	BA-003; CNTO-136	Phase 2 Clinical	Glaxosmithkline Plc, Johnson & Johnson Innovative Medicine	Arthritis, Rheumatoid; Asthma; Coronavirus Disease 2019 (COVID-19); Depressive Disorder, Major; Giant Cell Arteritis; Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic; Lupus Nephritis; Polymyalgia Rheumatica	상세
Anti-interleukin-6 receptor monoclonal antibody (Biocad)		Phase 2 Clinical	BIOCAD JSC	Autoimmune Diseases	상세
Isomyosamine	MYMD-1	Phase 2 Clinical	Mymd Pharmaceuticals Inc	Anxiety; Arthritis, Rheumatoid; Coronavirus Disease 2019 (COVID-19); Depression; Frailty; Hashimoto Disease; Healthy Aging; Inflammation; Sarcopenia	상세
FB-704A	FB-704; FB-704A	Phase 2 Clinical	Fountain Biopharma Inc	Arthritis, Rheumatoid; Asthma	상세
Gerilimzumab	GB-224; RYI-008; ARGX-109	Phase 1 Clinical	Argenx Se	Arthritis, Rheumatoid	상세
Tocilizumab biosimilar (Gedeon Richter/Mochida Pharmaceutical)		Phase 1 Clinical	Mycenax Biotech Inc	Arthritis, Rheumatoid	상세
GFS-202-A	GFS-202-A; GFS202A	Phase 1 Clinical	Genfleet Therapeutics (Shanghai) Co Ltd	Cachexia	상세
SCD-153	SCD-153	Phase 1 Clinical	Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Johns Hopkins University, Sun Pharma Advanced Research Company Ltd	Alopecia Areata	상세
NEX-20A	NEX-20A	Phase 1 Clinical	Nanexa AB	Multiple Myeloma	상세
Luxeptinib	CG026806; CG-806; CG’806; CG-026806	Phase 1 Clinical	Crystalgenomics Inc	Hematologic Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Myelodysplastic Syndromes	상세
Wogonin			China Pharmaceutical University, Daewoong Pharmaceutical Co Ltd, Hefei Cosource Medicine Technology, Shandong Buchang Pharmaceuticals Co Ltd		상세

시판 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	가장 빠른 브랜드 이름	가장 빠른 승인 국가	가장 빠른 적응증	가장 빠른 승인 회사	가장 빠른 승인 날짜	적응증	임상 시험
Luminol sodium	MP-1032	Approved	Metrio, Selvim			Psoriasis; Immune System Diseases	null	1997-01-01	Coronavirus Disease 2019 (COVID-19); Immune System Diseases; Plaque psoriasis; Psoriasis	상세
Pomalidomide	IMID-4047; CDC-394; CC-4047; IMiD-1	Approved	Celgene Corp	Imnovid, Actimid, Pomalyst/Imnovid, 安跃, Pomalyst	United States	Multiple Myeloma	Bristol-Myers Squibb Company	2013-02-08	Anemia, Sickle Cell; Atypical Squamous Cells of the Cervix; Bone Marrow Neoplasms; Carcinoma, Small Cell; Central Nervous System Neoplasms; Glioma; Graft vs Host Disease; Hodgkin Disease; Immunoglobulin Light-chain Amyloidosis; Lung Diseases, Interstitial; Lymphoma, Non-Hodgkin; Medulloblastoma; Multiple Myeloma; Myeloproliferative Disorders; Neurofibromatosis 1; Optic Nerve Glioma; Pancreatic Neoplasms; Plasmacytoma; Polycythemia Vera; Primary Myelofibrosis; Prostatic Neoplasms; Pulmonary Fibrosis; Renal Insufficiency; Sarcoma; Sarcoma, Kaposi; Scleroderma, Systemic; Solid tumours; Thrombocytosis; Waldenstrom Macroglobulinemia	상세
Siltuximab	cCLB-8; CNTO-328	Approved	Johnson & Johnson	Sylvant	United States	Multicentric Castleman's Disease (MCD)	Recordati Rare Diseases Inc	2014-04-23	Bone Marrow Neoplasms; Carcinoma, Renal Cell; Castleman Disease; Colorectal Neoplasms; Cytokine Release Syndrome; Diabetes Mellitus, Type 1; Head and Neck Neoplasms; Immunoglobulin Light-chain Amyloidosis; Kidney Neoplasms; Lung Diseases; Lung Neoplasms; Lymphoma, Non-Hodgkin; Monoclonal Gammopathy of Undetermined Significance; Multicentric Castleman's Disease (MCD); Multiple Myeloma; Myelodysplastic Syndromes; Neoplasms, Plasma Cell; Ovarian Neoplasms; Pancreatic Neoplasms; Pneumonia; Polycythemia Vera; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Primary Myelofibrosis; Prostatic Neoplasms; Psychotic Disorders; Rejection of lung transplantation; Respiratory Distress Syndrome, Adult; Respiratory Tract Diseases; Respiratory Tract Infections; Schizophrenia; Smoldering Multiple Myeloma; Thrombocytopenia	상세
Andrographolide/Sodium Hydrogen Sulfite		Approved							Bacterial Infections	상세
Thalidomide	NSC-66847; NSC-527179; K-17; FPF-300; FPF300	Approved	Celgene Corp	Talizer, Thalidomide Celgene, Thalidomide Pharmion, Synovir, Thalomid, Thaled	Mainland China	Leprosy, Lepromatous; Multiple Myeloma	Changzhou Pharmaceutical Factory	1982-01-01	Acquired Immunodeficiency Syndrome; Adenocarcinoma, Clear Cell; Adenoma, Islet Cell; Amyotrophic Lateral Sclerosis; Anemia, Refractory; Anemia, Refractory, with Excess of Blasts; Anemia, Sideroblastic; Angiodysplasia; Appendiceal Neoplasms; Arachnoiditis; Arteriovenous Malformations; Axial Spondyloarthritis; beta-Thalassemia; Burning Mouth Syndrome; Carcinoid Tumor; Carcinoma, Adenosquamous; Carcinoma, Hepatocellular; Cholangitis, Sclerosing; Colorectal Neoplasms; Cough; Endometrial Neoplasms; Endometriosis; Epilepsy; Erythema Nodosum; Gastric Antral Vascular Ectasia; Gastrointestinal Hemorrhage; Genetic Diseases, Inborn; Glioma; Graft vs Host Disease; Head and Neck Neoplasms; Hemoglobinopathies; HIV Infections; HIV Wasting Syndrome; Hodgkin Disease; Hormone-Resistant Prostate Neoplasms; Hypertension, Portal; Idiopathic Pulmonary Fibrosis; Kidney Neoplasms; Leiomyosarcoma; Leprosy, Lepromatous; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelomonocytic, Chronic; Liver Neoplasms; Lung Neoplasms	상세