언어 선택

IL-5 R alpha

IL-5 R alpha 분자 정보

영어 이름	Interleukin-5 receptor subunit alpha	시판 약물 수	1
임상 약물 수	2	표적 별명	Interleukin 5 Receptor， Alpha，Interleukin-5 Receptor Subunit Alpha，HSIL5R3，Interleukin-5 Receptor Alpha Chain，CDw125，Interleukin-5 Receptor alpha Subunit，Interleukin 5 Receptor Type 3，CD125 Antigen，Interleukin 5 Receptor Subunit Alpha，IL-5 Receptor Subunit Alpha，IL-5R-Alpha，IL5R，IL5RA，CD125，IL-5RA，IL-5R Subunit Alpha
최고 연구 개발 단계	Approved

영어 이름	Interleukin-5 receptor subunit alpha
표적 별명	Interleukin 5 Receptor， Alpha，Interleukin-5 Receptor Subunit Alpha，HSIL5R3，Interleukin-5 Receptor Alpha Chain，CDw125，Interleukin-5 Receptor alpha Subunit，Interleukin 5 Receptor Type 3，CD125 Antigen，Interleukin 5 Receptor Subunit Alpha，IL-5 Receptor Subunit Alpha，IL-5R-Alpha，IL5R，IL5RA，CD125，IL-5RA，IL-5R Subunit Alpha
시판 약물 수	1
임상 약물 수	2
최고 연구 개발 단계	Approved

IL-5 R alpha 제품 목록

속성
Protein (4)
제품 라이브러리
온라인 (4)
종
Human (3)Mouse (1)
태그
His Tag (2)Fc Tag (1)Avi Tag & Fc Tag (1)
마커
Unconjugated (3)Biotin-labeled (1)

제품 번호	종	발현 시스템	제품 설명
ILA-H5269	Human	HEK293	Human IL-5 R alpha / CD125 Protein, Fc Tag (MALS verified)
ILA-H52H4	Human	HEK293	Human IL-5 R alpha / CD125 Protein, His Tag, low endotoxin (MALS verified)
ILA-H82F5	Human	HEK293	Biotinylated Human IL-5 R alpha / CD125 Protein, Avitag™,Fc Tag (MALS verified)
ILA-M52H7	Mouse	HEK293	Mouse IL-5 R alpha / CD125 Protein, His Tag (MALS & SPR verified)

총 수량4

IL-5 R alpha분자 배경

Interleukin-5 receptor subunit alpha (IL5RA) is also known as IL-5 receptor subunit alpha, IL-5R subunit alpha and CD125,which is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and type 5 subfamily.IL5R, a heterodimer of an alpha and a beta subunit, is expressed on eosinophils and basophils. IL5RA / CD125 is the receptor for interleukin-5 (IL5) and the alpha chain can bind to IL5. The WSXWS motif of IL5RA appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.The beta subunit of IL5R is common to the IL3, IL5 and GM-CSF receptors.

IL-5 R alpha분자 별명

IL5Ra,CD125

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
IL-5 CAR-T Cell Therapy (Zhejiang University)		Phase 1 Clinical	Zhejiang University	Hematologic Diseases; Neoplasms	상세
Trabikibart	CSL-311	Phase 1 Clinical	Csl Ltd	Asthma	상세

시판 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	가장 빠른 브랜드 이름	가장 빠른 승인 국가	가장 빠른 적응증	가장 빠른 승인 회사	가장 빠른 승인 날짜	적응증	임상 시험
Benralizumab	KHK-4563; MEDI-563; BIW-8405; BIW-8405-IL-5R	Approved	Biowa Inc, Medimmune Llc	Fasenra, 凡舒卓	United States	Asthma	Astrazeneca Ab	2017-11-14	Asthma; Asthma, Exercise-Induced; Bronchiectasis; Chronic Urticaria; Dermatitis; Dermatitis, Atopic; Drug Hypersensitivity Syndrome; Eczema; Eosinophilia; Eosinophilic Asthma; Eosinophilic Esophagitis; Eosinophilic gastroenteritis (EG); Eosinophilic Granulomatosis With Polyangiitis; Gastroenteritis; Genetic Diseases, Inborn; Granulomatosis with Polyangiitis; Hematologic Diseases; Hypereosinophilic Syndrome; Hypersensitivity; Hypersensitivity, Immediate; Immune System Diseases; Leukocyte Disorders; Nasal Polyps; Pemphigoid, Bullous; Pulmonary Disease, Chronic Obstructive; Respiratory Tract Diseases; Sinusitis; Skin Diseases; Skin Diseases, Eczematous; Skin Diseases, Genetic	상세