언어 선택

IL-5

IL-5 분자 정보

영어 이름	Interleukin-5	시판 약물 수	3
임상 약물 수	6	표적 별명	T-cell replacing factor，IL5，Interleukin 5，Eosinophil Differentiation Factor，Colony-Stimulating Factor， Eosinophil，B-Cell Differentiation Factor I，Interleukin-5，IL-5，TRF，Interleukin 5 (Colony-Stimulating Factor， Eosinophil)，B Cell Differentiation Factor I，EDF
최고 연구 개발 단계	Approved

영어 이름	Interleukin-5
표적 별명	T-cell replacing factor，IL5，Interleukin 5，Eosinophil Differentiation Factor，Colony-Stimulating Factor， Eosinophil，B-Cell Differentiation Factor I，Interleukin-5，IL-5，TRF，Interleukin 5 (Colony-Stimulating Factor， Eosinophil)，B Cell Differentiation Factor I，EDF
시판 약물 수	3
임상 약물 수	6
최고 연구 개발 단계	Approved

IL-5 제품 목록

속성
Protein (8)Kits (2)
제품 라이브러리
온라인 (10)
종
Human (5)Rabbit (1)Mouse (1)Cynomolgus (1)Canine (1)Rat (1)
태그
His Tag (6)His Tag & Avi Tag (1)- (2)Tag Free (1)
마커
Unconjugated (7)Biotin-labeled (1)- (2)

제품 번호	종	발현 시스템	제품 설명
HOT IL5-H52H3	Human	HEK293	Human IL-5 Protein, His Tag
HOT IL5-H82Q5	Human	HEK293	Biotinylated Human IL-5 Protein, His,Avitag™ (MALS verified)
HOT IL5-C52H3	Cynomolgus	HEK293	Cynomolgus IL-5 Protein, His Tag, low endotoxin
HOT IL5-R52H4	Rabbit	HEK293	Rabbit IL-5 Protein, His Tag
CEA-C011	Human	-	Human IL-5 ELISA Kit
EP-128	Human	-	IL-5 [Biotinylated] : IL-5Rα Inhibitor Screening ELISA Kit
IL5-H5214	Human	HEK293	Human IL-5 Protein, premium grade
IL5-M52H3	Mouse	HEK293	Mouse IL-5 Protein, His Tag (MALS verified)
IL5-C5243	Canine	HEK293	Canine IL-5 Protein, His Tag (MALS verified)
IL5-R5243	Rat	HEK293	Rat IL-5 Protein, His Tag (MALS verified)

총 수량10

IL-5분자 배경

Interleukin 5 (IL5) is an interleukin produced by type-2 T helper cells and mast cells. IL-5 is a 115-amino acid (in human, 133 in the mouse) -long TH2 cytokine that is part of the hematopoietic family. Unlike other members of this cytokine family (namely interleukin 3 and GM-CSF), this glycoprotein in its active form is a homodimer. Interleukin-5 has long been associated with the cause of several allergic diseases including allergic rhinitis and asthma, wherein a large increase in the number of circulating, airway tissue, and induced sputum eosinophils have been observed. Given the high concordance of eosinophils and, in particular, allergic asthma pathology, it has been widely speculated that eosinophils have an important role in the pathology of this disease. Drugs that target IL-5 are mepolizumab and reslizumab.

IL-5분자 별명

IL-5,TRF,IL5,Interleukin-5

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Recombinant anti-IL-5 humanized monoclonal antibody (Shanghai CP Guojian)	610; SSGJ-610	Phase 3 Clinical	Sunshine GuoJian Pharmaceutical (Shanghai) Co Ltd	Asthma; Autoimmune Diseases	상세
SHR-1703	SHR-1703	Phase 3 Clinical	Jiangsu Hengrui Medicine Co Ltd	Asthma; Eosinophilic Asthma; Eosinophilic Granulomatosis With Polyangiitis	상세
RC-1416	RC14/16; RC-1416	Phase 2 Clinical	Nanjing RegeneCore Biotech Co Ltd	Asthma; Dermatitis, Atopic; Pulmonary Disease, Chronic Obstructive	상세
long-acting anti-IL-5 mAb (GSK)		Phase 1 Clinical	Glaxosmithkline Plc	Asthma	상세
Mepolizumab biosimilar(Bio Thera Solutions)	BAT2606; BAT-2606	Phase 1 Clinical	Bio-Thera Solutions Ltd	Asthma; Autoimmune Diseases; Nasal Polyps; Sinusitis	상세
Mepolizumab biosimilar (CTTQ Pharma)	TQC-3566; TQC3566	Phase 1 Clinical	Nanjing Shunxin Pharmaceuticals Co Ltd Of Chiatai Tianqing Pharmaceutical Group	Asthma; Eosinophilic Granuloma; Eosinophilic Granulomatosis With Polyangiitis; Granulomatosis with Polyangiitis; Hypereosinophilic Syndrome; Lymphohistiocytosis, Hemophagocytic; Nasal Polyps; Sinusitis; Vasculitis	상세

시판 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	가장 빠른 브랜드 이름	가장 빠른 승인 국가	가장 빠른 적응증	가장 빠른 승인 회사	가장 빠른 승인 날짜	적응증	임상 시험
Reslizumab	CEP-38072; SCH-5570; TRFK-5; SCH-55700; CDP-835; CTx-55700	Approved	Teva Pharmaceutical Industries Ltd	Cinquil, Cinqair, Cinqaero	United States	Asthma	Teva Respiratory Llc	2016-03-23	Asthma; Bronchitis; Eosinophilic Esophagitis; Hypereosinophilic Syndrome; Loiasis; Pulmonary Eosinophilia	상세
Depemokimab	GSK-3511294; AQ82742999; GSK3511294; GSK-294; GSK294	Approved	Glaxosmithkline Plc	易适来, Exdensur	United Kingdom	Asthma; Sinusitis; Nasal Polyps	Glaxosmithkline Plc	2025-12-15	Asthma; Chronic rhinosinusitis with nasal polyps (CRSwNP); Eosinophilic Asthma; Eosinophilic Granuloma; Eosinophilic Granulomatosis With Polyangiitis; Hypereosinophilic Syndrome; Nasal Polyps; Pulmonary Disease, Chronic Obstructive; Sinusitis; Vasculitis	상세
Mepolizumab	SB-240563; 240563	Approved	Glaxosmithkline Plc	Bosatria, Nucala, 美泊利珠单抗, 新可来	United States	Asthma	Glaxosmithkline Llc	2015-11-04	Angioedema; Asthma; Bronchitis; Chronic rhinosinusitis with nasal polyps (CRSwNP); Chronic Urticaria; Dermatitis, Atopic; Eosinophilia; Eosinophilic Esophagitis; Eosinophilic Granulomatosis With Polyangiitis; Fasciitis; Granulomatosis with Polyangiitis; Hypereosinophilic Syndrome; Nasal Polyps; Pulmonary Disease, Chronic Obstructive; Sinusitis; Virus Diseases	상세