언어 선택

IL-3 R alpha

IL-3 R alpha 분자 정보

영어 이름	Interleukin-3 receptor subunit alpha	시판 약물 수	1
임상 약물 수	40	표적 별명	IL3RY，IL-3RA，CD123 Antigen，IL3RX，IL-3R Subunit Alpha，IL3R，IL-3 Receptor Subunit Alpha，IL-3 Receptor Alpha SP2 Isoform，Interleukin 3 Receptor Subunit Alpha，IL3RAY，IL-3R-Alpha，CD123，HIL-3Ra，IL3RA，Interleukin 3 Receptor， Alpha (Low Affinity)，Interleukin-3 Receptor Subunit Alpha，Interleukin-3 Receptor alpha Subunit
최고 연구 개발 단계	Approved

영어 이름	Interleukin-3 receptor subunit alpha
표적 별명	IL3RY，IL-3RA，CD123 Antigen，IL3RX，IL-3R Subunit Alpha，IL3R，IL-3 Receptor Subunit Alpha，IL-3 Receptor Alpha SP2 Isoform，Interleukin 3 Receptor Subunit Alpha，IL3RAY，IL-3R-Alpha，CD123，HIL-3Ra，IL3RA，Interleukin 3 Receptor， Alpha (Low Affinity)，Interleukin-3 Receptor Subunit Alpha，Interleukin-3 Receptor alpha Subunit
시판 약물 수	1
임상 약물 수	40
최고 연구 개발 단계	Approved

IL-3 R alpha 제품 목록

속성
Protein (13)
제품 라이브러리
온라인 (13)
종
Human (10)Cynomolgus (1)Mouse (1)Canine (1)
태그
His Tag (7)Llama IgG Fc Tag (1)His Tag & Avi Tag (1)Fc Tag (2)Fc Tag & Avi Tag (1)Avi Tag (1)
마커
Unconjugated (6)FITC Labeled (2)Biotin-labeled (3)PE Labeled (1)APC Labeled (1)

제품 번호	종	발현 시스템	제품 설명
HOT ILA-H52H6	Human	HEK293	Human IL-3 R alpha / CD123 Protein, His Tag, low endotoxin (MALS & SPR verified)
HOT ILA-H8214	Human	HEK293	Biotinylated Human IL-3 R alpha / CD123 Protein, Avitag™ (MALS verified)
HOT ILA-H82F3	Human	HEK293	Biotinylated Human IL-3 R alpha / CD123 Protein, Fc,Avitag™ (MALS verified)
HOT ILA-H82H5	Human	HEK293	Biotinylated Human IL-3 R alpha / CD123 Protein, His,Avitag™, premium grade
HOT ILA-C52H6	Cynomolgus	HEK293	Cynomolgus IL-3 R alpha / CD123 Protein, His Tag (SPR verified)
ILA-H5252	Human	HEK293	Human IL-3 R alpha / CD123 Protein, Fc Tag (MALS & SPR verified)
ILA-H5255	Human	HEK293	Human IL-3 R alpha / CD123 Protein, Llama IgG2b Fc Tag, low endotoxin
ILA-HA2H8	Human	HEK293	APC-Labeled Human IL-3 R alpha / CD123 Protein, His Tag (Site-specific conjugation)
ILA-HF253	Human	HEK293	FITC-Labeled Human IL-3 R alpha / CD123 Protein, Fc Tag
ILA-HF2H9	Human	HEK293	FITC-Labeled Human IL-3 R alpha / CD123 Protein, His Tag

총 수량13

IL-3 R alpha분자 배경

Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.

IL-3 R alpha분자 별명

IL3R,IL3RA,IL-3Ra,IL-3R-alpha,IL3RAY,IL3RX,IL3RY,CD123 antigen,CD123,hIL3Ra,hIL-3Ra,MGC34174,IL-3 R alpha

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Talacotuzumab	CSL-362; JNJ-473; CSL-362-AML; JNJ-56022473; IL-13 MAb-CSL	Phase 2 Clinical	Csl Ltd	Leukemia, Myeloid, Acute; Myelodysplastic Syndromes	상세
Vibecotamab	XmAb-14045	Phase 2 Clinical	Xencor Inc	Blastic Plasmacytoid Dendritic Cell Neoplasm; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	상세
CD123 CAR-T cell therapy(Chongqing Precision Biotechnology)		Phase 2 Clinical	Chongqing Precision Biotechnology Co Ltd	Blastic Plasmacytoid Dendritic Cell Neoplasm; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute	상세
Anti-CD123 CAR T-cell therapy (Southwest Hospital)		Phase 2 Clinical	The Southwest Hospital of AMU	Leukemia; Leukemia, Myeloid	상세
CD33-CD123-CLL1 CART-T cell therapy (Hebei Taihe Chunyu Biotechnology)		Phase 2 Clinical	Hebei Tahoe Chunyu Biotechnology Co Ltd	Leukemia, Myeloid	상세
CAR-T Cells Targeting CD33/CD123 therapy(Essen Biotech)	BAH244; BAH-244	Phase 2 Clinical	Essen Biotech	Leukemia, Myeloid, Acute	상세
AZD-9829	AZD9829; AZD-9829	Phase 2 Clinical	Astrazeneca Plc	Hematologic Diseases; Hematologic Neoplasms; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes	상세
Anti Tim-3/CD123 CAR-T Cell Therapy(Xuzhou Medical University)		Phase 2 Clinical	The Affiliated Hospital Of Xuzhou Medical University, Xuzhou Medical University (Xzmu)	Leukemia, Myeloid, Acute	상세
MP0533	MP0533	Phase 2 Clinical	Molecular Partners Ag	Leukemia, Myeloid, Acute	상세
Mipletamig	APVO-436; APVO436	Phase 2 Clinical	Aptevo	Leukemia, Myeloid, Acute; Myelodysplastic Syndromes	상세
Anti-CD123 CAR T-cell therapy (University of Pennsylvania/Novartis)	JEZ-567	Phase 1 Clinical	Novartis Pharma Ag, University Of Pennsylvania	Leukemia, Myeloid, Acute	상세
Flotetuzumab	S-80880; MGD-006; RES-234	Phase 1 Clinical	Macrogenics Inc	Blastic Plasmacytoid Dendritic Cell Neoplasm; Hematologic Neoplasms; Hodgkin Disease; Leukemia; Leukemia, Biphenotypic, Acute; Leukemia, Hairy Cell; Leukemia, Myelogenous, Chronic; Leukemia, Myeloid, Acute; Mastocytosis, Systemic; Neoplasms, Plasma Cell; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	상세
UCART-123	UCART-123; UCART-123v1.2	Phase 1 Clinical	Cellectis Sa	Blastic Plasmacytoid Dendritic Cell Neoplasm; Leukemia, Myeloid, Acute	상세
Anti-CD123 CAR T cell therapy (Shanghai GeneChem)		Phase 1 Clinical	Shanghai Genechem Co Ltd	Leukemia, Myeloid, Acute	상세
Anti-CD123 CAR T-cell therapy (Nanjing Legend Biotech)		Phase 1 Clinical		Leukemia, Myeloid, Acute	상세
MB-102 (Mustang Bio)	MB-102	Phase 1 Clinical	City Of Hope National Medical Center, Mustang Bio Inc	Blastic Plasmacytoid Dendritic Cell Neoplasm; Leukemia, Biphenotypic, Acute; Leukemia, Myeloid, Acute; Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma	상세
ACLX-002	ACLX-002	Phase 1 Clinical	Arcellx Inc	Leukemia, Myeloid, Acute; Myelodysplastic Syndromes	상세
MGD-024	MGD-024	Phase 1 Clinical	Macrogenics Inc	Blastic Plasmacytoid Dendritic Cell Neoplasm; Hodgkin Disease; Leukemia, B-Cell; Leukemia, Hairy Cell; Leukemia, Myelogenous, Chronic; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Neoplasms	상세
AFM-28	AFM-28	Phase 1 Clinical	Affimed	Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Neoplasms	상세
VIP943	BAY-943; VIP-943	Phase 1 Clinical	Bayer AG	Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	상세
Anti-CD123 LV redirected T cells Therapy (Childrens Hospital of Philadelphia)	CART123	Phase 1 Clinical	Childrens Hospital of Philadelphia	Leukemia, Myeloid, Acute	상세
JY-017	JY017; JY-017	Phase 1 Clinical	Institute Of Hematology & Blood Diseases Hospital	Leukemia, Myeloid, Acute	상세
ACLX-004	ACLX-004	Phase 1 Clinical	Arcellx Inc	Leukemia, Myeloid, Acute; Myelodysplastic Syndromes	상세
Donor-derived CD123-CD16 bispecific antibody-modified NK cells therapy(Chinese PLA General Hospital)		Phase 1 Clinical	Pla General Hospital	Leukemia, Myeloid, Acute	상세
Autologous CAR123 T lymphocytes cell tharapy(Institute of Hematology and Blood Transfusion, Czech Republic)		Phase 1 Clinical	Institute of Hematology and Blood Transfusion, Czech Republic	Blastic Plasmacytoid Dendritic Cell Neoplasm; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma	상세
Anti-CD123 CAR NK cells therapy(Chongqing Precision Biotechnology)		Phase 1 Clinical	Chongqing Precision Biotechnology Co Ltd	Leukemia, Myeloid, Acute; Neoplasms, Plasma Cell	상세
RJK-RT2831	RJK-RT2831; RJKRT2831; RT-2831; RT2831	Phase 1 Clinical	Nanjing RegeneCore Biotech Co Ltd	Hematologic Neoplasms	상세
CD123 CAR-NK cell therapy(Beijing JD Biotech)	JD123; JD-123	Phase 1 Clinical	Beijing JD Biotech Co Ltd	Leukemia, Myeloid, Acute	상세
Universal CAR-T Cells therapy(Shenzhen Geno-Immune Medical Institute)		Phase 1 Clinical	Shenzhen Geno-Immune Medical Institute	Leukemia, Myeloid, Acute	상세
AVC-201	AVC-201; Allo-RevCAR01-T-CD123	Phase 1 Clinical	AvenCell Europe GmbH	Leukemia, Myeloid, Acute	상세
CD123-CAR T cells(St Jude Children's Research Hospital)		Phase 1 Clinical	St. Jude Children'S Research Hospital	Blastic Plasmacytoid Dendritic Cell Neoplasm; Myelodysplastic Syndromes; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma	상세
LAVA-1266	LAVA1266; LAVA-1266	Phase 1 Clinical	Lava Therapeutics NV	Hematologic Neoplasms; Leukemia, Myeloid, Acute	상세
Allogenic CD123-CAR-NK Cells therapy(JD Biotech)	JD023	Phase 1 Clinical	Beijing JD Biotech Co Ltd, Chinese Academy Of Military Medical Sciences	Leukemia, Myeloid, Acute	상세
BYON-4413	BYON-4413	Phase 1 Clinical	Byondis Bv	Hematologic Neoplasms; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes	상세
GR-1901	GR1901; GR-1901	Phase 1 Clinical	Chongqing Genrix Biopharmaceutical Co Ltd, Genrix (Shanghai) Biopharmaceutical Co Ltd	Leukemia, Myeloid, Acute	상세
SQZ-622(Novartis Pharma)	SQZ-622	Phase 1 Clinical	Novartis Pharma Ag	Leukemia, Myeloid, Acute	상세
SAR-443579	SAR-443579; SAR443579; SAR'579; IPH6101; IPH-6101	Phase 1 Clinical	Sanofi	Blastic Plasmacytoid Dendritic Cell Neoplasm; Hematologic Diseases; Leukemia, B-Cell; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma	상세
UniCAR02-T	UniCAR02-T	Phase 1 Clinical	Cellex Patient Treatment Gmbh	Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Kidney Neoplasms; Prostatic Neoplasms	상세
IL3 CAR T-cell therapy (Yake Biotechnology)		Phase 1 Clinical	Zhejiang University	Leukemia, Myeloid, Acute	상세
Anti-CD123 chimeric antigen receptor T cell therapy (Yake Biotechnology)		Clinical	Shanghai YaKe Biotechnology Co Ltd	Leukemia, Myeloid, Acute	상세

시판 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	가장 빠른 브랜드 이름	가장 빠른 승인 국가	가장 빠른 적응증	가장 빠른 승인 회사	가장 빠른 승인 날짜	적응증	임상 시험
Tagraxofusp	SL-401; DTIL-3; DT388 IL3	Approved	Texas A&M University Development Foundation	Elzonris	United States	Blastic Plasmacytoid Dendritic Cell Neoplasm	Stemline Therapeutics Inc	2018-12-21	Blastic Plasmacytoid Dendritic Cell Neoplasm; Leukemia; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Lymphoma; Multiple Myeloma; Myelodysplastic Syndromes; Primary Myelofibrosis	상세

제품 리뷰

A***r2026-03-11
0사람들이 좋아합니다
Human IL-3 R alpha / CD123 Protein, His Tag, low endotoxin (MALS & SPR verified)
We've always had a pleasure experience with AcroBio. Products are always top quality, quote requests come back super quick, and everyone is very kind. Great, great team to work with!
C***e2023-05-23
0사람들이 좋아합니다
Biotinylated Human IL-3 R alpha / CD123 Protein, Fc,Avitag™ (MALS verified)
We used Biotinylated Human IL-3 R alpha / CD123 Protein, Fc,Avitag™ (MALS verified) for a viral titer assay with Jurkat cells and received excellent results. We had a great experience ordering from the Acro biosystems website, which was easy to navigate. The reconstitution directions were very helpful and clear and each vial lasted for several experiments. The shipping was very quick and we look forward to ordering more products from Acro.
Y***a2022-05-10
0사람들이 좋아합니다
Biotinylated Human IL-3 R alpha / CD123 Protein, His,Avitag™, premium grade
We received the product at a reasonably fast speed. We used this product in ELISA. The product is robust and of good quality. The characterization information was accurate, reliable, and valuable for further calculations.