언어 선택

IL-22 R alpha 1

IL-22 R alpha 1 분자 정보

영어 이름	Interleukin-22 receptor	시판 약물 수	0
임상 약물 수	5	표적 별명
최고 연구 개발 단계	Phase 2 Clinical

영어 이름	Interleukin-22 receptor
표적 별명
시판 약물 수	0
임상 약물 수	5
최고 연구 개발 단계	Phase 2 Clinical

IL-22 R alpha 1 제품 목록

속성
Protein (5)
제품 라이브러리
온라인 (5)
종
Mouse (1)Cynomolgus (1)Human (3)
태그
His Tag (3)Fc Tag (1)His Tag & Avi Tag (1)
마커
Unconjugated (4)Biotin-labeled (1)

제품 번호	종	발현 시스템	제품 설명
IL1-H5257	Human	HEK293	Human IL-22 R alpha 1 Superstable Mutant Protein, Fc Tag (MALS verified)
IL1-H52H7	Human	HEK293	Human IL-22 R alpha 1 Superstable Mutant Protein, His Tag (MALS & SPR verified)
IL1-H82E5	Human	HEK293	Biotinylated Human IL-22 R alpha 1 Superstable Mutant Protein, His,Avitag™ (HPLC verified)
IL1-M52H8	Mouse	HEK293	Mouse IL-22 R alpha 1 Protein, His Tag (MALS & SPR verified)
IL1-C52H7	Cynomolgus	HEK293	Cynomolgus IL-22 R alpha 1 Protein, His Tag (MALS & SPR verified)

총 수량5

IL-22 R alpha 1분자 배경

Interleukin-22 receptor subunit alpha-1(IL22RA1) is a component of the receptor for IL20, IL22 and IL24.Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Efmarodocokin alfa	RO-7021610; UTTR-1147A; RG-7880	Phase 2 Clinical	Genentech Inc	Colitis, Ulcerative; Coronavirus Disease 2019 (COVID-19); Crohn Disease; Diabetic Foot; Graft vs Host Disease	상세
Temtokibart	ARGX-112; LEO-138559; LP-0145	Phase 2 Clinical	Argenx Se, Leo Pharma Inc	Dermatitis, Atopic	상세
CK-0045	CK-0045	Phase 2 Clinical	Cytoki Pharma ApS	Diabetes Mellitus, Type 2; Obesity; Overweight	상세
Eflepedocokin alfa	F-652	Phase 2 Clinical	Evive Biotech Ltd	Acute-On-Chronic Liver Failure; Coronavirus Disease 2019 (COVID-19); Enteritis; Enterocolitis, Necrotizing; Graft vs Host Disease; Hepatitis, Alcoholic; Pancreatitis	상세
ABBV-022	ABBV-022	Phase 1 Clinical	Abbvie Inc	Colitis, Ulcerative	상세