언어 선택

IL-17A

IL-17A 분자 정보

영어 이름	Interleukin 17A	시판 약물 수	6
임상 약물 수	28	표적 별명	Interleukin 17 (Cytotoxic T-Lymphocyte-Associated Serine Esterase 8)，CTLA8，IL17A，Interleukin 17A，Cytotoxic T-Lymphocyte-Associated Antigen 8，Cytotoxic T-Lymphocyte-Associated Protein 8，CTLA-8，IL-17A，IL-17，IL17，Interleukin-17A
최고 연구 개발 단계	Approved

영어 이름	Interleukin 17A
표적 별명	Interleukin 17 (Cytotoxic T-Lymphocyte-Associated Serine Esterase 8)，CTLA8，IL17A，Interleukin 17A，Cytotoxic T-Lymphocyte-Associated Antigen 8，Cytotoxic T-Lymphocyte-Associated Protein 8，CTLA-8，IL-17A，IL-17，IL17，Interleukin-17A
시판 약물 수	6
임상 약물 수	28
최고 연구 개발 단계	Approved

IL-17A 제품 목록

속성
Protein (8)Kits (4)
제품 라이브러리
온라인 (11)연구 중 (1)
종
Mouse (1)Human (7)Cynomolgus (2)Canine (1)Rat (1)
태그
His Tag (5)His Tag & Avi Tag (2)Tag Free (1)- (4)
마커
Unconjugated (6)Biotin-labeled (2)- (4)

제품 번호	종	발현 시스템	제품 설명
HOT ILA-H5219	Human	HEK293	Human IL-17A / CTLA-8 Protein, premium grade
HOT ILA-H5243	Human	HEK293	Human IL-17A / CTLA-8 Protein, His Tag, low endotoxin (HPLC verified)
HOT ILA-H82Q1	Human	HEK293	Biotinylated Human IL-17A / CTLA-8 Protein, His,Avitag™ (MALS verified)
HOT CT8-M5240	Mouse	HEK293	Mouse IL-17A / CTLA-8 Protein, His Tag, low endotoxin (MALS verified)
CEA-C092	Human	-	Human IL-17A / CTLA8 ELISA Kit
EP-139	Human	-	IL-17A [Biotinylated] : IL-17RA Inhibitor Screening ELISA Kit
FCSh-018	Human	-	Human IL-17A Detection Kit (Flow Cytometry Bead Assay)
FRT-P011	Human	-	Human IL-17A / IL-17RA Inhibitor Screening Kit (TR-FRET)
ILA-C5249	Cynomolgus	HEK293	Cynomolgus IL-17A / CTLA-8 Protein, His Tag, low endotoxin (MALS verified)
ILA-C52H7	Canine	HEK293	Canine IL-17A / CTLA-8 Protein, His Tag (HPLC verified)

총 수량12

IL-17A분자 배경

Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

IL-17A분자 별명

IL-17A,Interleukin-17A,CTLA-8,IL-17

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
HB-0017	HB-0017; HB0017	Phase 3 Clinical	HuaBo Biopharm Co Ltd, Shanghai Huaota Biopharmaceutical Co Ltd, Zhejiang Huahai Pharmaceutical Co Ltd	Arthritis, Psoriatic; Hidradenitis Suppurativa; Plaque psoriasis; Psoriasis; Spondylarthritis; Spondylitis, Ankylosing	상세
Izokibep	IMG-020; IMG020; ABY-035/AFO2; IMG-20; ABY-035; AFB-035	Phase 3 Clinical	Affibody Ab	Arthritis, Psoriatic; Plaque psoriasis; Psoriasis; Spondylitis, Ankylosing	상세
Sonelokimab	ALX-0761; MSB-0010841; M-1095	Phase 3 Clinical	Ablynx Nv	Arthritis, Psoriatic; Hidradenitis Suppurativa; Psoriasis	상세
Secukinumab Biosimilar(Celltrion)	CT-P55	Phase 3 Clinical	Celltrion Inc	Multiple Sclerosis; Plaque psoriasis	상세
Secukinumab biosimilar (CSPC Pharmaceutical Group)	SYS6012; SYS-6012	Phase 3 Clinical	CSPC Pharmaceutical Group Ltd	Plaque psoriasis	상세
SCT-650C	SCT650C; SCT-650-C; SCT-650C	Phase 3 Clinical	SinoCelltech Ltd	Arthritis, Rheumatoid; Autoimmune Diseases; Axial Spondyloarthritis; Hidradenitis Suppurativa; Plaque psoriasis; Spondylarthritis; Spondylitis, Ankylosing	상세
Secukinumab Biosimilar(Mabtech)	CMAB-015; CMAB015	Phase 3 Clinical	Taizhou Mabtech Pharmaceutical Co Ltd	Plaque psoriasis; Psoriasis; Spondylitis, Ankylosing	상세
DMT-310	DMT-310	Phase 3 Clinical	Dermata	Acne Vulgaris; Rosacea	상세
Tibulizumab	LY-3090106; LY3090106; ZB-106	Phase 2 Clinical	Eli Lilly And Company	Arthritis, Rheumatoid; Hidradenitis Suppurativa; Scleroderma, Systemic; Sjogren's Syndrome; Sjogren-Larsson Syndrome	상세
ORKA-002	ORKA-002; PR-029; ORKA-021	Phase 2 Clinical	Paragon Therapeutics Inc	Arthritis, Psoriatic; Plaque psoriasis; Psoriasis	상세
SIM-0335	SIM-0335; SIM-335	Phase 2 Clinical	BCY Pharm Co Ltd	Plaque psoriasis	상세
Simepdekinra	DC-853; LY4100511; LY-4100511	Phase 2 Clinical	Dice Therapeutics Inc	Immune System Diseases; Plaque psoriasis	상세
Isomyosamine	MYMD-1	Phase 2 Clinical	Mymd Pharmaceuticals Inc	Anxiety; Arthritis, Rheumatoid; Coronavirus Disease 2019 (COVID-19); Depression; Frailty; Hashimoto Disease; Healthy Aging; Inflammation; Sarcopenia	상세
ZL-1102	ZL-1102; CB-001	Phase 2 Clinical	Crescendo Biologics Ltd	Plaque psoriasis; Psoriasis	상세
CNTO-6785	CNTO-6785; FTC-001	Phase 1 Clinical	Johnson & Johnson Innovative Medicine, Morphosys Ag	Arthritis, Psoriatic; Arthritis, Rheumatoid; Psoriasis; Pulmonary Disease, Chronic Obstructive; Spondylitis, Ankylosing	상세
JNJ-61178104	JNJ-61178104	Phase 1 Clinical	Johnson & Johnson Innovative Medicine	Autoimmune Diseases	상세
Secukinumab biosimilar (BioRay Pharmaceutical)	BR-201	Phase 1 Clinical	Zhejiang BioRay Biopharmaceuticals Co Ltd	Autoimmune Diseases; Plaque psoriasis; Psoriasis; Spondylitis, Ankylosing	상세
CT-P52	CT-P52	Phase 1 Clinical	Celltrion Inc		상세
HGP-3918	HGP-3918; HGP3918	Phase 1 Clinical	Hitgen Inc	Inflammation	상세
JNJ-63823539	JNJ-63823539	Phase 1 Clinical	Johnson & Johnson Innovative Medicine	Arthritis, Rheumatoid	상세
BR-2021	BR2021; BR-2021	Phase 1 Clinical	Boryung Pharmaceutical Co Ltd	Pancreatic Neoplasms	상세
KYS-202004-A	KYS202004A; KYS-202004-A	Phase 1 Clinical	Jiangsu Kanion Pharmaceutical Co Ltd	Psoriasis	상세
Secukinumab biosimilar (Gan & Lee)	GLR1023; GLR-1023	Phase 1 Clinical	Gan & Lee Pharmaceuticals	Plaque psoriasis	상세
anti-IL-17A humanized monoclonal antibody(Fontacea )		Phase 1 Clinical	Shandong Fangtansi Biopharmaceutical Co Ltd	Plaque psoriasis	상세
UA-026	UA-026	Phase 1 Clinical	Yousen Jianheng Biomedical (Shanghai) Co Ltd	Autoimmune Diseases; Plaque psoriasis; Psoriasis	상세
LEO-153339	LEO-153339	Phase 1 Clinical	Leo Pharma Inc		상세
HY-1770	HY-1770; HT-17; HT17; YF02; HT25; GH02; HY1770	Phase 1 Clinical	Suzhou Pharmavan Co Ltd	Dermatitis, Atopic; Plaque psoriasis	상세
UCB-0159	UCB-0159	Phase 1 Clinical	Ucb Sa	Autoimmune Diseases	상세

시판 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	가장 빠른 브랜드 이름	가장 빠른 승인 국가	가장 빠른 적응증	가장 빠른 승인 회사	가장 빠른 승인 날짜	적응증	임상 시험
Amdokitug	608; SSGJ-608	Approved	Sunshine GuoJian Pharmaceutical (Shanghai) Co Ltd	益赛拓	Mainland China	Plaque psoriasis	Sunshine GuoJian Pharmaceutical (Shanghai) Co Ltd	2026-02-10	Axial Spondyloarthritis; Non-radiographic axial spondyloarthritis; Plaque psoriasis; Psoriasis; Spondylarthritis; Spondylitis, Ankylosing	상세
Vunakizumab	SHR-1314	Approved	Jiangsu Hengrui Medicine Co Ltd	安达静	Mainland China	Plaque psoriasis	Suzhou Suncadia Biopharmaceuticals Co Ltd	2024-08-20	Arthritis, Psoriatic; Autoimmune Diseases; Axial Spondyloarthritis; Graves Disease; Graves Ophthalmopathy; Lupus Nephritis; Non-radiographic axial spondyloarthritis; Plaque psoriasis; Psoriasis; Spondylarthritis; Spondylitis, Ankylosing	상세
Ixekizumab	LY-2439821	Approved	Eli Lilly And Company	拓咨, Taltz	United States	Psoriasis	Eli Lilly And Company	2016-03-22	Arthritis, Psoriatic; Arthritis, Rheumatoid; Axial Spondyloarthritis; Depressive Disorder, Major; Diabetes Mellitus, Type 1; Idiopathic Subglottic Stenosis; Lichen Planus; Non-radiographic axial spondyloarthritis; Pemphigoid, Bullous; Pityriasis Rubra Pilaris; Plaque psoriasis; Psoriasis; Pyoderma Gangrenosum; Spondylarthritis; Spondylitis, Ankylosing	상세
Xeligekimab	GR-1501	Approved	Chongqing Genrix Biopharmaceutical Co Ltd, Genrix (Shanghai) Biopharmaceutical Co Ltd	金立希	Mainland China	Plaque psoriasis	Chongqing Genrix Biopharmaceutical Co Ltd	2024-08-20	Axial Spondyloarthritis; Lupus Nephritis; Non-radiographic axial spondyloarthritis; Plaque psoriasis; Psoriasis; Spondylarthritis	상세
Virulizin		Approved	Aptose	Virulizin, Virulizin-2 gamma	Mexico	Colorectal Neoplasms; Stomach Neoplasms; Pancreatic Neoplasms; Uterine Cervical Neoplasms; Sarcoma, Kaposi; Melanoma; Carcinoma, Renal Cell	null	1997-01-01	Carcinoma, Renal Cell; Colorectal Neoplasms; Melanoma; Pancreatic Neoplasms; Sarcoma, Kaposi; Stomach Neoplasms; Uterine Cervical Neoplasms	상세
Secukinumab	KB-03303A; NVP-AIN-457; AIN-457	Approved	Novartis Pharma Ag	Cosentyx, 可善挺, Scapho	Japan	Arthritis, Psoriatic; Psoriasis	Novartis Pharma Ag	2014-12-26	Alopecia Areata; Arthritis; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; Asthma; Axial Spondyloarthritis; Behcet Syndrome; Crohn Disease; Dermatitis, Atopic; Diabetes Mellitus, Type 1; Gastroenteritis; Giant Cell Arteritis; Graves Ophthalmopathy; Hidradenitis Suppurativa; Hyperkeratosis, Epidermolytic; Ichthyosiform Erythroderma, Congenital; Ichthyosis; Ichthyosis, Lamellar; Inflammation; Inflammatory Bowel Diseases; Lichen Planus; Lupus Erythematosus, Discoid; Lupus Nephritis; Melanoma; Metabolic Dysfunction-Associated Steatotic Liver Disease; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Necrobiosis Lipoidica; Netherton Syndrome; Non-radiographic axial spondyloarthritis; Palmoplantar pustulosis; Plaque psoriasis; Polymyalgia Rheumatica; Psoriasis; Pyoderma Gangrenosum; Rotator Cuff Injuries; Spondylarthritis; Spondylarthropathies; Spondylitis, Ankylosing; Tendinopathy; Tendon Injuries; Uveitis	상세