IL-17 RB 분자 정보
Molecule Name
Interleukin-17 receptor B
분자 별명
IL-17 RB,Interleukin-17 receptor B,Interleukin-17 receptor B,Cytokine receptor-like 4,IL-17 receptor homolog 1,IL-17Rh1,IL17Rh1,Interleukin-17B receptor,IL-17B receptor,IL17RB,CRL4, EVI27, IL17BR
Drug Development Progress
임상 약물 수1
시판 약물 수0
최고 연구 개발 단계Phase 2 Clinical
표적 별명
IL-17 receptor B，IL-17RB，Cytokine receptor-like 4，IL-17 receptor homolog 1，IL-17Rh1，IL17Rh1，Interleukin-17B receptor，IL-17B receptor
분자 배경
IL17RB (EVI27, IL17Rh1) is a single pass transmembrane receptor which belongs to IL17R family of cytokine receptors. It was found to be expressed in liver, brain, testis and lungs. The ligand for IL17RB is IL17E, also known as IL25. The five IL-17 receptors (IL17RA-IL17RE) exhibit considerable sequence divergence between one another, but all appear to contain extracellular domains composed of fibronectin type-III (FnIII) domains, and cytoplasmic SEF/IL-17R (SEFIR) domains that show loose homology to Toll/IL-1R (TLR) domains.
IL-17 RB 제품 목록
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임상 약물 정보
| 영어 이름 | 연구 코드 | 연구 개발 단계 | 회사 | 적응증 | 임상 시험 |
|---|---|---|---|---|---|
| SM-17 | SM-17; SM17 | Phase 2 Clinical | Sinomab Bioscience Ltd | Asthma; Dermatitis, Atopic; Idiopathic Pulmonary Fibrosis; Inflammatory Bowel Diseases | 상세 |